Phenotype measure:   Chesler2   GRA

ID, description, units MPD:43418   GRA   granulocyte count (GRA; units per volume x 103)   [n/µL]
Data set, strains Chesler2   CC diallel w/par   38 strains     sex: both     age: 7-15wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - granulocyte count (GRA; units per volume x 103)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 2.20 3.40 4.50 4.35 3.50
A ♀ 6.60 5.40 3.30
B6 ♀ 6.60 6.60 2.30 3.10 7.10 3.10
CAST ♀ 2.90 3.60 1.96 3.08 3.64 5.50
NOD ♀ 4.10 7.10 7.53 8.25
NZO ♀ 7.80 4.30 3.00
PWK ♀ 2.60 3.60 6.00 5.00
WSB ♀ 2.20 2.50 4.25 2.10 3.77 1.50 1.20

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 4.10 3.75 3.20 8.45 5.15
A ♀ 4.22 5.32 5.74 3.00 6.50
B6 ♀ 3.20 3.26 9.95 6.80
CAST ♀ 4.85 5.55 3.57 3.45 3.80 3.30 2.48
NOD ♀ 5.10 5.95
NZO ♀ 4.60 9.00
PWK ♀ 1.90 5.85
WSB ♀ 5.40 5.17 4.93 4.15 4.95 5.40

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains33 strains
Mean of the strain means4.20   n/µL 4.91   n/µL
Median of the strain means3.62   n/µL 4.93   n/µL
SD of the strain means± 1.91 ± 1.79
Coefficient of variation (CV)0.454 0.365
Min–max range of strain means1.20   –   8.25   n/µL 1.90   –   9.95   n/µL
Mean sample size per strain1.9   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.6417 1.6417 0.4957 0.483
strain 10 180.2601 18.026 5.4431 < 0.0001
sex:strain 10 50.1469 5.0147 1.5142 0.1453
Residuals 100 331.1717 3.3117


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.2 0.566   2   0.4 0.257 1.8, 2.6 -1.05
129S1/SvImJ m 4.1 2.12   2   1.5 0.517 2.6, 5.6 -0.45
129SAF1 f 3.4 0.0   1   0.0 0.0 3.4, 3.4 -0.42
129SAF1 m 3.75 1.77   2   1.25 0.471 2.5, 5.0 -0.65
129SB6F1 f 4.5 1.41   2   1.0 0.314 3.5, 5.5 0.16
129SB6F1 m 3.2 0.424   2   0.3 0.133 2.9, 3.5 -0.95
129SCASTF1 f 4.35 1.06   2   0.75 0.244 3.6, 5.1 0.08
129SNODF1 m 8.45 1.06   2   0.75 0.126 7.7, 9.2 1.98
129SNZOF1 m 5.15 1.63   2   1.15 0.316 4.0, 6.3 0.13
129SPWKF1 f 3.5 0.0   1   0.0 0.0 3.5, 3.5 -0.37
AB6F1 f 5.4 0.0   1   0.0 0.0 5.4, 5.4 0.63
AB6F1 m 5.32 0.793   4 0.397 0.149 4.5, 6.3 0.23
A/J f 6.6 3.68   2   2.6 0.557 4.0, 9.2 1.26
A/J m 4.22 1.54   6 0.628 0.365 2.3, 6.6 -0.39
ANODF1 m 5.74 2.44   7 0.924 0.426 2.0, 9.7 0.46
ANZOF1 f 3.3 0.0   1   0.0 0.0 3.3, 3.3 -0.47
APWKF1 m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -1.07
AWSBF1 m 6.5 0.0   1   0.0 0.0 6.5, 6.5 0.89
B6129SF1/J f 6.6 1.84   2   1.3 0.279 5.3, 7.9 1.26
B6AF1/J f 6.6 0.0   1   0.0 0.0 6.6, 6.6 1.26
B6AF1/J m 3.2 0.0   1   0.0 0.0 3.2, 3.2 -0.95
B6NODF1 f 3.1 0.0   1   0.0 0.0 3.1, 3.1 -0.58
B6NODF1 m 9.95 3.32   2   2.35 0.334 7.6, 12.3 2.81
B6NZOF1 f 7.1 0.0   1   0.0 0.0 7.1, 7.1 1.52
B6NZOF1 m 6.8 0.0   1   0.0 0.0 6.8, 6.8 1.05
B6PWKF1 f 3.1 0.0   1   0.0 0.0 3.1, 3.1 -0.58
C57BL/6J f 2.3 0.967   20 0.216 0.421 1.1, 4.3 -1.0
C57BL/6J m 3.26 1.53   37 0.251 0.469 1.2, 7.3 -0.92
CAST129SF1 m 4.85 0.495   2   0.35 0.102 4.5, 5.2 -0.03
CASTAF1 f 2.9 0.0   1   0.0 0.0 2.9, 2.9 -0.68
CASTAF1 m 5.55 0.495   2   0.35 0.0892 5.2, 5.9 0.36
CASTB6F1 f 3.6 0.0   1   0.0 0.0 3.6, 3.6 -0.31
CASTB6F1 m 3.57 2.0   3 1.16 0.562 1.5, 5.5 -0.75
CAST/EiJ f 1.96 0.439   5 0.196 0.224 1.4, 2.4 -1.17
CAST/EiJ m 3.45 0.0707   2   0.05 0.0205 3.4, 3.5 -0.82
CASTNODF1 m 3.8 0.0   1   0.0 0.0 3.8, 3.8 -0.62
CASTNZOF1 f 3.08 2.0   4 0.999 0.65 1.2, 4.9 -0.59
CASTNZOF1 m 3.3 0.0   1   0.0 0.0 3.3, 3.3 -0.9
CASTPWKF1 f 3.64 0.832   5 0.372 0.229 2.8, 4.9 -0.29
CASTPWKF1 m 2.48 0.85   6 0.347 0.342 1.6, 3.7 -1.36
CASTWSBF1 f 5.5 1.98   2   1.4 0.36 4.1, 6.9 0.68
NODAF1 f 4.1 0.0   1   0.0 0.0 4.1, 4.1 -0.05
NODB6F1 f 7.1 2.36   3 1.37 0.333 4.4, 8.8 1.52
NODNZOF1 f 8.25 2.9   2   2.05 0.351 6.2, 10.3 2.13
NODNZOF1 m 5.95 4.03   2   2.85 0.677 3.1, 8.8 0.58
NOD/ShiLtJ f 7.53 1.18   3 0.684 0.157 6.8, 8.9 1.75
NOD/ShiLtJ m 5.1 2.79   3 1.61 0.547 2.8, 8.2 0.11
NZO129SF1 f 7.8 0.0   1   0.0 0.0 7.8, 7.8 1.89
NZOAF1 f 4.3 0.0   1   0.0 0.0 4.3, 4.3 0.05
NZOB6F1 m 4.6 0.0   1   0.0 0.0 4.6, 4.6 -0.17
NZO/HlLtJ m 9.0 0.0   1   0.0 0.0 9.0, 9.0 2.28
NZOWSBF1 f 3.0 0.6   3 0.346 0.2 2.4, 3.6 -0.63
PWK129SF1 f 2.6 0.0   1   0.0 0.0 2.6, 2.6 -0.84
PWKAF1 f 3.6 0.0   1   0.0 0.0 3.6, 3.6 -0.31
PWKAF1 m 1.9 0.0   1   0.0 0.0 1.9, 1.9 -1.68
PWKNODF1 f 6.0 0.0   1   0.0 0.0 6.0, 6.0 0.95
PWK/PhJ f 5.0 0.849   2   0.6 0.17 4.4, 5.6 0.42
PWK/PhJ m 5.85 5.64   4 2.82 0.965 1.0, 14.0 0.52
WSB129SF1 f 2.2 0.0   1   0.0 0.0 2.2, 2.2 -1.05
WSBAF1 f 2.5 0.0   1   0.0 0.0 2.5, 2.5 -0.89
WSBAF1 m 5.4 0.849   2   0.6 0.157 4.8, 6.0 0.27
WSBB6F1 f 4.25 2.19   2   1.55 0.516 2.7, 5.8 0.03
WSBB6F1 m 5.17 1.65   3 0.953 0.319 3.8, 7.0 0.14
WSBCASTF1 m 4.93 1.19   3 0.689 0.242 4.1, 6.3 0.01
WSB/EiJ f 1.2 0.283   2   0.2 0.236 1.0, 1.4 -1.57
WSB/EiJ m 5.4 0.0   1   0.0 0.0 5.4, 5.4 0.27
WSBNODF1 f 2.1 0.0   1   0.0 0.0 2.1, 2.1 -1.1
WSBNODF1 m 4.15 2.62   2   1.85 0.63 2.3, 6.0 -0.42
WSBNZOF1 f 3.77 2.14   6 0.873 0.568 1.4, 6.6 -0.22
WSBNZOF1 m 4.95 2.4   4 1.2 0.484 2.3, 8.0 0.02
WSBPWKF1 f 1.5 0.283   2   0.2 0.189 1.3, 1.7 -1.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.2 1.2868 4.753 0.0
129S1/SvImJ m 4.1 1.2868 6.653 1.547
129SB6F1 f 4.5 1.2868 7.053 1.947
129SB6F1 m 3.2 1.2868 5.753 0.647
A/J f 6.6 1.2868 9.153 4.047
A/J m 4.2167 0.7429 5.6906 2.7427
C57BL/6J f 2.3 0.4069 3.1073 1.4927
C57BL/6J m 3.2649 0.2992 3.8584 2.6713
CAST/EiJ f 1.96 0.8138 3.5746 0.3454
CAST/EiJ m 3.45 1.2868 6.003 0.897
CASTPWKF1 f 3.64 0.8138 5.2546 2.0254
CASTPWKF1 m 2.4833 0.7429 3.9573 1.0094
NODNZOF1 f 8.25 1.2868 10.803 5.697
NODNZOF1 m 5.95 1.2868 8.503 3.397
NOD/ShiLtJ f 7.5333 1.0507 9.6178 5.4488
NOD/ShiLtJ m 5.1 1.0507 7.1845 3.0155
PWK/PhJ f 5.0 1.2868 7.553 2.447
PWK/PhJ m 5.85 0.9099 7.6552 4.0448
WSBB6F1 f 4.25 1.2868 6.803 1.697
WSBB6F1 m 5.1667 1.0507 7.2512 3.0822
WSBNZOF1 f 3.7667 0.7429 5.2406 2.2927
WSBNZOF1 m 4.95 0.9099 6.7552 3.1448


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.15 0.9099 4.9552 1.3448
129SB6F1 both 3.85 0.9099 5.6552 2.0448
A/J both 5.4083 0.7429 6.8823 3.9344
C57BL/6J both 2.7824 0.2525 3.2835 2.2814
CAST/EiJ both 2.705 0.7613 4.2154 1.1946
CASTPWKF1 both 3.0617 0.551 4.1548 1.9685
NODNZOF1 both 7.1 0.9099 8.9052 5.2948
NOD/ShiLtJ both 6.3167 0.7429 7.7906 4.8427
PWK/PhJ both 5.425 0.788 6.9884 3.8616
WSBB6F1 both 4.7083 0.8306 6.3563 3.0604
WSBNZOF1 both 4.3583 0.5873 5.5236 3.1931




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA