Phenotype measure:   Chesler2   pct_MONO

ID, description, units MPD:43417   pct_MONO   monocyte differential (MONO; percentage of viable WBC)   [%]
Data set, strains Chesler2   CC diallel w/par   38 strains     sex: both     age: 7-15wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - monocyte differential (MONO; percentage of viable WBC)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 11.7 10.9 10.3 9.95 12.3
A ♀ 9.85 10.2 11.8
B6 ♀ 10.1 10.0 10.2 9.70 9.10 9.70
CAST ♀ 8.20 9.60 8.94 9.10 8.48 9.05
NOD ♀ 10.6 9.93 10.3 9.65
NZO ♀ 10.2 10.9 10.8
PWK ♀ 13.2 10.9 9.10 11.4
WSB ♀ 12.2 12.2 9.55 10.2 10.3 10.6 14.6

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 11.8 10.4 10.8 10.4 10.3
A ♀ 10.1 9.57 9.86 9.60 9.60
B6 ♀ 9.80 8.60 8.85 8.80
CAST ♀ 9.00 8.80 9.67 9.90 9.90 10.0 8.67
NOD ♀ 9.50 9.90
NZO ♀ 10.8 10.7
PWK ♀ 11.0 11.5
WSB ♀ 9.50 9.43 9.23 10.4 9.65 10.8

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains33 strains
Mean of the strain means10.4   % 9.90   %
Median of the strain means10.2   % 9.86   %
SD of the strain means± 1.30 ± 0.797
Coefficient of variation (CV)0.125 0.0805
Min–max range of strain means8.20   –   14.6   % 8.60   –   11.8   %
Mean sample size per strain1.9   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 14.6595 14.6595 20.3301 < 0.0001
strain 10 69.9044 6.9904 9.6945 < 0.0001
sex:strain 10 21.0315 2.1032 2.9167 0.003
Residuals 100 72.1075 0.7211


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 11.7 0.849   2   0.6 0.0725 11.1, 12.3 0.99
129S1/SvImJ m 11.8 1.41   2   1.0 0.12 10.8, 12.8 2.38
129SAF1 f 10.9 0.0   1   0.0 0.0 10.9, 10.9 0.37
129SAF1 m 10.4 0.495   2   0.35 0.0474 10.1, 10.8 0.62
129SB6F1 f 10.3 0.354   2   0.25 0.0342 10.1, 10.6 -0.09
129SB6F1 m 10.8 0.0   2   0.0 0.0 10.8, 10.8 1.12
129SCASTF1 f 9.95 0.354   2   0.25 0.0355 9.7, 10.2 -0.36
129SNODF1 m 10.4 0.141   2   0.1 0.0136 10.3, 10.5 0.62
129SNZOF1 m 10.3 0.283   2   0.2 0.0275 10.1, 10.5 0.5
129SPWKF1 f 12.3 0.0   1   0.0 0.0 12.3, 12.3 1.45
AB6F1 f 10.2 0.0   1   0.0 0.0 10.2, 10.2 -0.17
AB6F1 m 9.57 0.222   4 0.111 0.0232 9.4, 9.9 -0.42
A/J f 9.85 0.636   2   0.45 0.0646 9.4, 10.3 -0.43
A/J m 10.1 0.724   6 0.296 0.0717 9.1, 10.8 0.25
ANODF1 m 9.86 0.443   7 0.167 0.0449 9.1, 10.5 -0.06
ANZOF1 f 11.8 0.0   1   0.0 0.0 11.8, 11.8 1.06
APWKF1 m 9.6 0.0   1   0.0 0.0 9.6, 9.6 -0.38
AWSBF1 m 9.6 0.0   1   0.0 0.0 9.6, 9.6 -0.38
B6129SF1/J f 10.1 0.636   2   0.45 0.0627 9.7, 10.6 -0.24
B6AF1/J f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.32
B6AF1/J m 9.8 0.0   1   0.0 0.0 9.8, 9.8 -0.13
B6NODF1 f 9.7 0.0   1   0.0 0.0 9.7, 9.7 -0.55
B6NODF1 m 8.85 0.495   2   0.35 0.0559 8.5, 9.2 -1.32
B6NZOF1 f 9.1 0.0   1   0.0 0.0 9.1, 9.1 -1.01
B6NZOF1 m 8.8 0.0   1   0.0 0.0 8.8, 8.8 -1.38
B6PWKF1 f 9.7 0.0   1   0.0 0.0 9.7, 9.7 -0.55
C57BL/6J f 10.2 0.749   20 0.168 0.0738 8.7, 11.3 -0.17
C57BL/6J m 8.6 0.723   37 0.119 0.0841 6.8, 10.2 -1.64
CAST129SF1 m 9.0 0.283   2   0.2 0.0314 8.8, 9.2 -1.13
CASTAF1 f 8.2 0.0   1   0.0 0.0 8.2, 8.2 -1.7
CASTAF1 m 8.8 0.283   2   0.2 0.0321 8.6, 9.0 -1.38
CASTB6F1 f 9.6 0.0   1   0.0 0.0 9.6, 9.6 -0.63
CASTB6F1 m 9.67 0.709   3 0.41 0.0734 8.9, 10.3 -0.29
CAST/EiJ f 8.94 1.51   5 0.676 0.169 6.7, 10.3 -1.13
CAST/EiJ m 9.9 1.41   2   1.0 0.143 8.9, 10.9 0.0
CASTNODF1 m 9.9 0.0   1   0.0 0.0 9.9, 9.9 0.0
CASTNZOF1 f 9.1 1.14   4 0.569 0.125 7.8, 10.4 -1.01
CASTNZOF1 m 10.0 0.0   1   0.0 0.0 10.0, 10.0 0.12
CASTPWKF1 f 8.48 0.438   5 0.196 0.0517 7.8, 8.9 -1.49
CASTPWKF1 m 8.67 1.07   6 0.438 0.124 7.3, 10.4 -1.55
CASTWSBF1 f 9.05 0.212   2   0.15 0.0234 8.9, 9.2 -1.05
NODAF1 f 10.6 0.0   1   0.0 0.0 10.6, 10.6 0.14
NODB6F1 f 9.93 1.07   3 0.617 0.108 8.7, 10.6 -0.37
NODNZOF1 f 9.65 0.212   2   0.15 0.022 9.5, 9.8 -0.59
NODNZOF1 m 9.9 0.99   2   0.7 0.1 9.2, 10.6 0.0
NOD/ShiLtJ f 10.3 0.416   3 0.24 0.0403 10.0, 10.8 -0.09
NOD/ShiLtJ m 9.5 1.06   3 0.611 0.111 8.3, 10.3 -0.51
NZO129SF1 f 10.2 0.0   1   0.0 0.0 10.2, 10.2 -0.17
NZOAF1 f 10.9 0.0   1   0.0 0.0 10.9, 10.9 0.37
NZOB6F1 m 10.8 0.0   1   0.0 0.0 10.8, 10.8 1.12
NZO/HlLtJ m 10.7 0.0   1   0.0 0.0 10.7, 10.7 1.0
NZOWSBF1 f 10.8 0.551   3 0.318 0.0512 10.2, 11.3 0.29
PWK129SF1 f 13.2 0.0   1   0.0 0.0 13.2, 13.2 2.14
PWKAF1 f 10.9 0.0   1   0.0 0.0 10.9, 10.9 0.37
PWKAF1 m 11.0 0.0   1   0.0 0.0 11.0, 11.0 1.37
PWKNODF1 f 9.1 0.0   1   0.0 0.0 9.1, 9.1 -1.01
PWK/PhJ f 11.4 0.0707   2   0.05 0.00623 11.3, 11.4 0.76
PWK/PhJ m 11.5 1.15   4 0.575 0.1 10.1, 12.9 2.0
WSB129SF1 f 12.2 0.0   1   0.0 0.0 12.2, 12.2 1.37
WSBAF1 f 12.2 0.0   1   0.0 0.0 12.2, 12.2 1.37
WSBAF1 m 9.5 0.566   2   0.4 0.0595 9.1, 9.9 -0.51
WSBB6F1 f 9.55 1.48   2   1.05 0.155 8.5, 10.6 -0.66
WSBB6F1 m 9.43 1.11   3 0.639 0.117 8.4, 10.6 -0.59
WSBCASTF1 m 9.23 0.503   3 0.291 0.0545 8.7, 9.7 -0.85
WSB/EiJ f 14.6 1.91   2   1.35 0.131 13.2, 15.9 3.21
WSB/EiJ m 10.8 0.0   1   0.0 0.0 10.8, 10.8 1.12
WSBNODF1 f 10.2 0.0   1   0.0 0.0 10.2, 10.2 -0.17
WSBNODF1 m 10.4 0.424   2   0.3 0.0408 10.1, 10.7 0.62
WSBNZOF1 f 10.3 1.06   6 0.435 0.104 9.1, 11.9 -0.09
WSBNZOF1 m 9.65 0.624   4 0.312 0.0647 8.8, 10.3 -0.32
WSBPWKF1 f 10.6 0.778   2   0.55 0.073 10.1, 11.2 0.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 11.7 0.6004 12.8913 10.5087
129S1/SvImJ m 11.8 0.6004 12.9913 10.6087
129SB6F1 f 10.35 0.6004 11.5413 9.1587
129SB6F1 m 10.8 0.6004 11.9913 9.6087
A/J f 9.85 0.6004 11.0413 8.6587
A/J m 10.1 0.3467 10.7878 9.4122
C57BL/6J f 10.15 0.1899 10.5267 9.7733
C57BL/6J m 8.6 0.1396 8.877 8.323
CAST/EiJ f 8.94 0.3798 9.6934 8.1866
CAST/EiJ m 9.9 0.6004 11.0913 8.7087
CASTPWKF1 f 8.48 0.3798 9.2334 7.7266
CASTPWKF1 m 8.6667 0.3467 9.3544 7.9789
NODNZOF1 f 9.65 0.6004 10.8413 8.4587
NODNZOF1 m 9.9 0.6004 11.0913 8.7087
NOD/ShiLtJ f 10.3333 0.4903 11.306 9.3607
NOD/ShiLtJ m 9.5 0.4903 10.4727 8.5273
PWK/PhJ f 11.35 0.6004 12.5413 10.1587
PWK/PhJ m 11.475 0.4246 12.3174 10.6326
WSBB6F1 f 9.55 0.6004 10.7413 8.3587
WSBB6F1 m 9.4333 0.4903 10.406 8.4607
WSBNZOF1 f 10.2833 0.3467 10.9711 9.5956
WSBNZOF1 m 9.65 0.4246 10.4924 8.8076


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.75 0.4246 12.5924 10.9076
129SB6F1 both 10.575 0.4246 11.4174 9.7326
A/J both 9.975 0.3467 10.6628 9.2872
C57BL/6J both 9.375 0.1178 9.6088 9.1412
CAST/EiJ both 9.42 0.3552 10.1248 8.7152
CASTPWKF1 both 8.5733 0.2571 9.0834 8.0633
NODNZOF1 both 9.775 0.4246 10.6174 8.9326
NOD/ShiLtJ both 9.9167 0.3467 10.6044 9.2289
PWK/PhJ both 11.4125 0.3677 12.142 10.683
WSBB6F1 both 9.4917 0.3876 10.2606 8.7227
WSBNZOF1 both 9.9667 0.2741 10.5104 9.4229




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA