Phenotype measure:   Chesler2   MONO

ID, description, units MPD:43416   MONO   monocyte count (MONO; units per volume x 103)   [n/µL]
Data set, strains Chesler2   CC diallel w/par   38 strains     sex: both     age: 7-15wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - monocyte count (MONO; units per volume x 103)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 0.800 0.600 1.05 0.800 1.30
A ♀ 1.25 1.20 0.900
B6 ♀ 1.35 1.30 0.715 0.800 1.40 0.800
CAST ♀ 0.400 0.700 0.380 0.600 0.840 1.00
NOD ♀ 1.00 1.43 1.50 1.50
NZO ♀ 1.60 0.900 0.667
PWK ♀ 1.00 0.800 1.00 1.35
WSB ♀ 0.700 0.700 0.850 0.600 0.850 0.500 0.450

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 1.10 1.00 1.00 1.60 1.10
A ♀ 0.867 1.20 1.14 0.800 1.10
B6 ♀ 0.800 0.816 1.65 1.30
CAST ♀ 0.900 1.00 0.800 0.850 0.700 0.800 0.550
NOD ♀ 0.933 1.10
NZO ♀ 1.20 2.10
PWK ♀ 0.600 1.32
WSB ♀ 1.00 1.03 0.967 0.900 1.07 1.20

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains33 strains
Mean of the strain means0.936   n/µL 1.05   n/µL
Median of the strain means0.850   n/µL 1.00   n/µL
SD of the strain means± 0.333 ± 0.307
Coefficient of variation (CV)0.356 0.294
Min–max range of strain means0.380   –   1.60   n/µL 0.550   –   2.10   n/µL
Mean sample size per strain1.9   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0151 0.0151 0.1844 0.6685
strain 10 4.7469 0.4747 5.7942 < 0.0001
sex:strain 10 1.7909 0.1791 2.1861 0.0245
Residuals 100 8.1924 0.0819


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.8 0.141   2   0.1 0.177 0.7, 0.9 -0.41
129S1/SvImJ m 1.1 0.141   2   0.1 0.129 1.0, 1.2 0.18
129SAF1 f 0.6 0.0   1   0.0 0.0 0.6, 0.6 -1.01
129SAF1 m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.15
129SB6F1 f 1.05 0.212   2   0.15 0.202 0.9, 1.2 0.34
129SB6F1 m 1.0 0.141   2   0.1 0.141 0.9, 1.1 -0.15
129SCASTF1 f 0.8 0.283   2   0.2 0.354 0.6, 1.0 -0.41
129SNODF1 m 1.6 0.283   2   0.2 0.177 1.4, 1.8 1.81
129SNZOF1 m 1.1 0.424   2   0.3 0.386 0.8, 1.4 0.18
129SPWKF1 f 1.3 0.0   1   0.0 0.0 1.3, 1.3 1.09
AB6F1 f 1.2 0.0   1   0.0 0.0 1.2, 1.2 0.79
AB6F1 m 1.2 0.216   4 0.108 0.18 0.9, 1.4 0.5
A/J f 1.25 0.495   2   0.35 0.396 0.9, 1.6 0.94
A/J m 0.867 0.372   6 0.152 0.43 0.5, 1.5 -0.58
ANODF1 m 1.14 0.45   7 0.17 0.394 0.5, 1.9 0.31
ANZOF1 f 0.9 0.0   1   0.0 0.0 0.9, 0.9 -0.11
APWKF1 m 0.8 0.0   1   0.0 0.0 0.8, 0.8 -0.8
AWSBF1 m 1.1 0.0   1   0.0 0.0 1.1, 1.1 0.18
B6129SF1/J f 1.35 0.212   2   0.15 0.157 1.2, 1.5 1.24
B6AF1/J f 1.3 0.0   1   0.0 0.0 1.3, 1.3 1.09
B6AF1/J m 0.8 0.0   1   0.0 0.0 0.8, 0.8 -0.8
B6NODF1 f 0.8 0.0   1   0.0 0.0 0.8, 0.8 -0.41
B6NODF1 m 1.65 0.636   2   0.45 0.386 1.2, 2.1 1.97
B6NZOF1 f 1.4 0.0   1   0.0 0.0 1.4, 1.4 1.39
B6NZOF1 m 1.3 0.0   1   0.0 0.0 1.3, 1.3 0.83
B6PWKF1 f 0.8 0.0   1   0.0 0.0 0.8, 0.8 -0.41
C57BL/6J f 0.715 0.181   20 0.0406 0.254 0.4, 1.0 -0.66
C57BL/6J m 0.816 0.242   37 0.0398 0.297 0.3, 1.4 -0.75
CAST129SF1 m 0.9 0.141   2   0.1 0.157 0.8, 1.0 -0.47
CASTAF1 f 0.4 0.0   1   0.0 0.0 0.4, 0.4 -1.61
CASTAF1 m 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.15
CASTB6F1 f 0.7 0.0   1   0.0 0.0 0.7, 0.7 -0.71
CASTB6F1 m 0.8 0.265   3 0.153 0.331 0.5, 1.0 -0.8
CAST/EiJ f 0.38 0.0837   5 0.0374 0.22 0.3, 0.5 -1.67
CAST/EiJ m 0.85 0.212   2   0.15 0.25 0.7, 1.0 -0.64
CASTNODF1 m 0.7 0.0   1   0.0 0.0 0.7, 0.7 -1.12
CASTNZOF1 f 0.6 0.424   4 0.212 0.707 0.2, 1.1 -1.01
CASTNZOF1 m 0.8 0.0   1   0.0 0.0 0.8, 0.8 -0.8
CASTPWKF1 f 0.84 0.134   5 0.06 0.16 0.7, 1.0 -0.29
CASTPWKF1 m 0.55 0.176   6 0.0719 0.32 0.4, 0.8 -1.61
CASTWSBF1 f 1.0 0.283   2   0.2 0.283 0.8, 1.2 0.19
NODAF1 f 1.0 0.0   1   0.0 0.0 1.0, 1.0 0.19
NODB6F1 f 1.43 0.351   3 0.203 0.245 1.1, 1.8 1.48
NODNZOF1 f 1.5 0.424   2   0.3 0.283 1.2, 1.8 1.69
NODNZOF1 m 1.1 0.424   2   0.3 0.386 0.8, 1.4 0.18
NOD/ShiLtJ f 1.5 0.173   3 0.1 0.115 1.3, 1.6 1.69
NOD/ShiLtJ m 0.933 0.586   3 0.338 0.628 0.5, 1.6 -0.37
NZO129SF1 f 1.6 0.0   1   0.0 0.0 1.6, 1.6 1.99
NZOAF1 f 0.9 0.0   1   0.0 0.0 0.9, 0.9 -0.11
NZOB6F1 m 1.2 0.0   1   0.0 0.0 1.2, 1.2 0.5
NZO/HlLtJ m 2.1 0.0   1   0.0 0.0 2.1, 2.1 3.44
NZOWSBF1 f 0.667 0.252   3 0.145 0.377 0.4, 0.9 -0.81
PWK129SF1 f 1.0 0.0   1   0.0 0.0 1.0, 1.0 0.19
PWKAF1 f 0.8 0.0   1   0.0 0.0 0.8, 0.8 -0.41
PWKAF1 m 0.6 0.0   1   0.0 0.0 0.6, 0.6 -1.45
PWKNODF1 f 1.0 0.0   1   0.0 0.0 1.0, 1.0 0.19
PWK/PhJ f 1.35 0.212   2   0.15 0.157 1.2, 1.5 1.24
PWK/PhJ m 1.32 0.826   4 0.413 0.623 0.3, 2.3 0.9
WSB129SF1 f 0.7 0.0   1   0.0 0.0 0.7, 0.7 -0.71
WSBAF1 f 0.7 0.0   1   0.0 0.0 0.7, 0.7 -0.71
WSBAF1 m 1.0 0.283   2   0.2 0.283 0.8, 1.2 -0.15
WSBB6F1 f 0.85 0.212   2   0.15 0.25 0.7, 1.0 -0.26
WSBB6F1 m 1.03 0.208   3 0.12 0.201 0.8, 1.2 -0.05
WSBCASTF1 m 0.967 0.153   3 0.0882 0.158 0.8, 1.1 -0.25
WSB/EiJ f 0.45 0.0707   2   0.05 0.157 0.4, 0.5 -1.46
WSB/EiJ m 1.2 0.0   1   0.0 0.0 1.2, 1.2 0.5
WSBNODF1 f 0.6 0.0   1   0.0 0.0 0.6, 0.6 -1.01
WSBNODF1 m 0.9 0.566   2   0.4 0.629 0.5, 1.3 -0.47
WSBNZOF1 f 0.85 0.321   6 0.131 0.378 0.3, 1.1 -0.26
WSBNZOF1 m 1.07 0.299   4 0.149 0.278 0.7, 1.4 0.08
WSBPWKF1 f 0.5 0.0   2   0.0 0.0 0.5, 0.5 -1.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.8 0.2024 1.2015 0.3985
129S1/SvImJ m 1.1 0.2024 1.5015 0.6985
129SB6F1 f 1.05 0.2024 1.4515 0.6485
129SB6F1 m 1.0 0.2024 1.4015 0.5985
A/J f 1.25 0.2024 1.6515 0.8485
A/J m 0.8667 0.1169 1.0985 0.6348
C57BL/6J f 0.715 0.064 0.842 0.588
C57BL/6J m 0.8162 0.0471 0.9096 0.7229
CAST/EiJ f 0.38 0.128 0.634 0.126
CAST/EiJ m 0.85 0.2024 1.2515 0.4485
CASTPWKF1 f 0.84 0.128 1.094 0.586
CASTPWKF1 m 0.55 0.1169 0.7818 0.3182
NODNZOF1 f 1.5 0.2024 1.9015 1.0985
NODNZOF1 m 1.1 0.2024 1.5015 0.6985
NOD/ShiLtJ f 1.5 0.1653 1.8279 1.1721
NOD/ShiLtJ m 0.9333 0.1653 1.2612 0.6055
PWK/PhJ f 1.35 0.2024 1.7515 0.9485
PWK/PhJ m 1.325 0.1431 1.6089 1.0411
WSBB6F1 f 0.85 0.2024 1.2515 0.4485
WSBB6F1 m 1.0333 0.1653 1.3612 0.7055
WSBNZOF1 f 0.85 0.1169 1.0818 0.6182
WSBNZOF1 m 1.075 0.1431 1.3589 0.7911


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.95 0.1431 1.2339 0.6661
129SB6F1 both 1.025 0.1431 1.3089 0.7411
A/J both 1.0583 0.1169 1.2902 0.8265
C57BL/6J both 0.7656 0.0397 0.8444 0.6868
CAST/EiJ both 0.615 0.1197 0.8526 0.3774
CASTPWKF1 both 0.695 0.0867 0.8669 0.5231
NODNZOF1 both 1.3 0.1431 1.5839 1.0161
NOD/ShiLtJ both 1.2167 0.1169 1.4485 0.9848
PWK/PhJ both 1.3375 0.1239 1.5834 1.0916
WSBB6F1 both 0.9417 0.1306 1.2009 0.6825
WSBNZOF1 both 0.9625 0.0924 1.1458 0.7792




  GENOME-WIDE ASSOCIATION (GWAS) STATIC PLOT
Plot generated with EMMA / pyLMM using 132K SNP array. Click on plot to view at larger size.