Phenotype measure:   Chesler2   LYM

ID, description, units MPD:43414   LYM   lymphocyte count (LYM; units per volume x 103)   [n/µL]
Data set, strains Chesler2   CC diallel w/par   38 strains     sex: both     age: 7-15wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - lymphocyte count (LYM; units per volume x 103)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 4.25 2.40 5.30 3.40 6.00
A ♀ 5.60 6.00 4.20
B6 ♀ 6.10 5.70 4.54 4.60 6.90 4.90
CAST ♀ 2.80 3.40 2.82 3.75 6.18 5.15
NOD ♀ 4.50 6.70 6.37 6.20
NZO ♀ 6.40 3.60 3.03
PWK ♀ 4.40 3.70 4.10 6.25
WSB ♀ 3.50 3.40 4.35 3.80 4.23 3.10 1.75

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 4.75 4.60 5.20 6.10 4.50
A ♀ 3.92 6.52 5.14 5.30 4.80
B6 ♀ 4.40 6.04 7.65 7.30
CAST ♀ 4.90 5.20 4.53 4.95 3.10 4.70 4.15
NOD ♀ 3.97 4.90
NZO ♀ 5.40 8.70
PWK ♀ 3.70 5.22
WSB ♀ 4.55 5.20 5.03 4.10 5.57 5.30

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains33 strains
Mean of the strain means4.56   n/µL 5.13   n/µL
Median of the strain means4.38   n/µL 4.95   n/µL
SD of the strain means± 1.34 ± 1.14
Coefficient of variation (CV)0.294 0.221
Min–max range of strain means1.75   –   6.90   n/µL 3.10   –   8.70   n/µL
Mean sample size per strain1.9   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 10.3841 10.3841 6.8523 0.0102
strain 10 34.2859 3.4286 2.2625 0.0198
sex:strain 10 62.3029 6.2303 4.1112 0.0001
Residuals 100 151.5425 1.5154


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.25 1.06   2   0.75 0.25 3.5, 5.0 -0.23
129S1/SvImJ m 4.75 0.636   2   0.45 0.134 4.3, 5.2 -0.34
129SAF1 f 2.4 0.0   1   0.0 0.0 2.4, 2.4 -1.61
129SAF1 m 4.6 0.0   1   0.0 0.0 4.6, 4.6 -0.47
129SB6F1 f 5.3 0.99   2   0.7 0.187 4.6, 6.0 0.55
129SB6F1 m 5.2 0.566   2   0.4 0.109 4.8, 5.6 0.06
129SCASTF1 f 3.4 2.12   2   1.5 0.624 1.9, 4.9 -0.87
129SNODF1 m 6.1 1.27   2   0.9 0.209 5.2, 7.0 0.85
129SNZOF1 m 4.5 1.7   2   1.2 0.377 3.3, 5.7 -0.56
129SPWKF1 f 6.0 0.0   1   0.0 0.0 6.0, 6.0 1.07
AB6F1 f 6.0 0.0   1   0.0 0.0 6.0, 6.0 1.07
AB6F1 m 6.52 1.24   4 0.622 0.191 5.1, 8.1 1.22
A/J f 5.6 2.26   2   1.6 0.404 4.0, 7.2 0.77
A/J m 3.92 1.3   6 0.533 0.333 2.7, 6.4 -1.07
ANODF1 m 5.14 2.04   7 0.771 0.397 2.3, 9.0 0.01
ANZOF1 f 4.2 0.0   1   0.0 0.0 4.2, 4.2 -0.27
APWKF1 m 5.3 0.0   1   0.0 0.0 5.3, 5.3 0.15
AWSBF1 m 4.8 0.0   1   0.0 0.0 4.8, 4.8 -0.29
B6129SF1/J f 6.1 0.707   2   0.5 0.116 5.6, 6.6 1.15
B6AF1/J f 5.7 0.0   1   0.0 0.0 5.7, 5.7 0.85
B6AF1/J m 4.4 0.0   1   0.0 0.0 4.4, 4.4 -0.64
B6NODF1 f 4.6 0.0   1   0.0 0.0 4.6, 4.6 0.03
B6NODF1 m 7.65 2.05   2   1.45 0.268 6.2, 9.1 2.21
B6NZOF1 f 6.9 0.0   1   0.0 0.0 6.9, 6.9 1.74
B6NZOF1 m 7.3 0.0   1   0.0 0.0 7.3, 7.3 1.91
B6PWKF1 f 4.9 0.0   1   0.0 0.0 4.9, 4.9 0.25
C57BL/6J f 4.54 0.889   20 0.199 0.196 3.2, 6.1 -0.02
C57BL/6J m 6.04 1.19   37 0.195 0.197 3.5, 8.6 0.8
CAST129SF1 m 4.9 0.99   2   0.7 0.202 4.2, 5.6 -0.21
CASTAF1 f 2.8 0.0   1   0.0 0.0 2.8, 2.8 -1.31
CASTAF1 m 5.2 0.707   2   0.5 0.136 4.7, 5.7 0.06
CASTB6F1 f 3.4 0.0   1   0.0 0.0 3.4, 3.4 -0.87
CASTB6F1 m 4.53 1.33   3 0.769 0.294 3.0, 5.4 -0.53
CAST/EiJ f 2.82 1.17   5 0.523 0.415 1.7, 4.7 -1.3
CAST/EiJ m 4.95 0.636   2   0.45 0.129 4.5, 5.4 -0.16
CASTNODF1 m 3.1 0.0   1   0.0 0.0 3.1, 3.1 -1.79
CASTNZOF1 f 3.75 1.92   4 0.96 0.512 1.4, 5.8 -0.61
CASTNZOF1 m 4.7 0.0   1   0.0 0.0 4.7, 4.7 -0.38
CASTPWKF1 f 6.18 0.455   5 0.203 0.0736 5.8, 6.9 1.21
CASTPWKF1 m 4.15 1.46   6 0.594 0.351 2.2, 5.8 -0.86
CASTWSBF1 f 5.15 0.0707   2   0.05 0.0137 5.1, 5.2 0.44
NODAF1 f 4.5 0.0   1   0.0 0.0 4.5, 4.5 -0.05
NODB6F1 f 6.7 1.41   3 0.814 0.211 5.2, 8.0 1.59
NODNZOF1 f 6.2 1.27   2   0.9 0.205 5.3, 7.1 1.22
NODNZOF1 m 4.9 0.99   2   0.7 0.202 4.2, 5.6 -0.21
NOD/ShiLtJ f 6.37 0.907   3 0.524 0.143 5.4, 7.2 1.35
NOD/ShiLtJ m 3.97 1.76   3 1.02 0.444 2.9, 6.0 -1.02
NZO129SF1 f 6.4 0.0   1   0.0 0.0 6.4, 6.4 1.37
NZOAF1 f 3.6 0.0   1   0.0 0.0 3.6, 3.6 -0.72
NZOB6F1 m 5.4 0.0   1   0.0 0.0 5.4, 5.4 0.23
NZO/HlLtJ m 8.7 0.0   1   0.0 0.0 8.7, 8.7 3.14
NZOWSBF1 f 3.03 1.85   3 1.07 0.61 0.9, 4.2 -1.14
PWK129SF1 f 4.4 0.0   1   0.0 0.0 4.4, 4.4 -0.12
PWKAF1 f 3.7 0.0   1   0.0 0.0 3.7, 3.7 -0.64
PWKAF1 m 3.7 0.0   1   0.0 0.0 3.7, 3.7 -1.26
PWKNODF1 f 4.1 0.0   1   0.0 0.0 4.1, 4.1 -0.34
PWK/PhJ f 6.25 0.778   2   0.55 0.124 5.7, 6.8 1.26
PWK/PhJ m 5.22 2.87   4 1.43 0.548 1.1, 7.4 0.08
WSB129SF1 f 3.5 0.0   1   0.0 0.0 3.5, 3.5 -0.79
WSBAF1 f 3.4 0.0   1   0.0 0.0 3.4, 3.4 -0.87
WSBAF1 m 4.55 1.77   2   1.25 0.389 3.3, 5.8 -0.51
WSBB6F1 f 4.35 1.34   2   0.95 0.309 3.4, 5.3 -0.16
WSBB6F1 m 5.2 0.872   3 0.503 0.168 4.2, 5.8 0.06
WSBCASTF1 m 5.03 0.929   3 0.536 0.185 4.0, 5.8 -0.09
WSB/EiJ f 1.75 0.778   2   0.55 0.444 1.2, 2.3 -2.1
WSB/EiJ m 5.3 0.0   1   0.0 0.0 5.3, 5.3 0.15
WSBNODF1 f 3.8 0.0   1   0.0 0.0 3.8, 3.8 -0.57
WSBNODF1 m 4.1 2.26   2   1.6 0.552 2.5, 5.7 -0.91
WSBNZOF1 f 4.23 1.31   6 0.534 0.309 2.1, 5.7 -0.25
WSBNZOF1 m 5.57 1.21   4 0.606 0.217 4.3, 7.2 0.38
WSBPWKF1 f 3.1 0.141   2   0.1 0.0456 3.0, 3.2 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.25 0.8705 5.977 2.523
129S1/SvImJ m 4.75 0.8705 6.477 3.023
129SB6F1 f 5.3 0.8705 7.027 3.573
129SB6F1 m 5.2 0.8705 6.927 3.473
A/J f 5.6 0.8705 7.327 3.873
A/J m 3.9167 0.5026 4.9137 2.9196
C57BL/6J f 4.545 0.2753 5.0911 3.9989
C57BL/6J m 6.0378 0.2024 6.4394 5.6363
CAST/EiJ f 2.82 0.5505 3.9122 1.7278
CAST/EiJ m 4.95 0.8705 6.677 3.223
CASTPWKF1 f 6.18 0.5505 7.2722 5.0878
CASTPWKF1 m 4.15 0.5026 5.1471 3.1529
NODNZOF1 f 6.2 0.8705 7.927 4.473
NODNZOF1 m 4.9 0.8705 6.627 3.173
NOD/ShiLtJ f 6.3667 0.7107 7.7767 4.9566
NOD/ShiLtJ m 3.9667 0.7107 5.3767 2.5566
PWK/PhJ f 6.25 0.8705 7.977 4.523
PWK/PhJ m 5.225 0.6155 6.4462 4.0038
WSBB6F1 f 4.35 0.8705 6.077 2.623
WSBB6F1 m 5.2 0.7107 6.6101 3.7899
WSBNZOF1 f 4.2333 0.5026 5.2304 3.2363
WSBNZOF1 m 5.575 0.6155 6.7962 4.3538


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.5 0.6155 5.7212 3.2788
129SB6F1 both 5.25 0.6155 6.4712 4.0288
A/J both 4.7583 0.5026 5.7554 3.7613
C57BL/6J both 5.2914 0.1708 5.6303 4.9525
CAST/EiJ both 3.885 0.515 4.9067 2.8633
CASTPWKF1 both 5.165 0.3727 5.9044 4.4256
NODNZOF1 both 5.55 0.6155 6.7712 4.3288
NOD/ShiLtJ both 5.1667 0.5026 6.1637 4.1696
PWK/PhJ both 5.7375 0.533 6.7951 4.6799
WSBB6F1 both 4.775 0.5619 5.8898 3.6602
WSBNZOF1 both 4.9042 0.3973 5.6924 4.1159




  GENOME-WIDE ASSOCIATION (GWAS) STATIC PLOT
Plot generated with EMMA / pyLMM using 132K SNP array. Click on plot to view at larger size.