Phenotype measure:   Chesler2   WBC

ID, description, units MPD:43413   WBC   white blood cell count (WBC; units per volume x 103)   [n/µL]
Data set, strains Chesler2   CC diallel w/par   38 strains     sex: both     age: 7-15wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - white blood cell count (WBC; units per volume x 103)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 7.23 6.42 10.9 8.56 10.8
A ♀ 13.4 12.6 8.43
B6 ♀ 14.0 13.6 7.56 8.49 15.4 8.77
CAST ♀ 6.06 7.67 5.54 7.47 10.7 11.6
NOD ♀ 9.63 15.2 15.4 16.0
NZO ♀ 15.8 8.80 6.71
PWK ♀ 8.00 8.10 11.1 12.6
WSB ♀ 6.38 6.55 9.48 6.50 8.85 5.12 3.43

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 9.96 8.79 9.42 16.2 10.7
A ♀ 9.00 13.0 12.0 9.12 12.4
B6 ♀ 8.40 10.1 19.2 15.4
CAST ♀ 10.7 11.8 8.90 9.26 7.59 8.82 7.16
NOD ♀ 10.00 11.9
NZO ♀ 11.2 19.9
PWK ♀ 6.19 12.4
WSB ♀ 11.0 11.4 10.9 9.15 11.6 11.9

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains33 strains
Mean of the strain means9.71   n/µL 11.1   n/µL
Median of the strain means8.79   n/µL 10.7   n/µL
SD of the strain means± 3.37 ± 3.03
Coefficient of variation (CV)0.347 0.274
Min–max range of strain means3.43   –   16.0   n/µL 6.19   –   19.9   n/µL
Mean sample size per strain1.9   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15.9828 15.9828 1.7084 0.1942
strain 10 255.0325 25.5032 2.7261 0.0053
sex:strain 10 244.4495 24.445 2.613 0.0073
Residuals 99 926.1604 9.3552


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.23 1.75   2   1.24 0.243 5.99, 8.47 -0.74
129S1/SvImJ m 9.96 2.88   2   2.03 0.289 7.93, 12.0 -0.37
129SAF1 f 6.42 0.0   1   0.0 0.0 6.42, 6.42 -0.98
129SAF1 m 8.79 2.63   2   1.86 0.299 6.93, 10.7 -0.75
129SB6F1 f 10.9 2.62   2   1.85 0.242 9.0, 12.7 0.35
129SB6F1 m 9.42 1.13   2   0.8 0.12 8.62, 10.2 -0.55
129SCASTF1 f 8.56 3.49   2   2.46 0.407 6.1, 11.0 -0.34
129SNODF1 m 16.2 2.62   2   1.85 0.162 14.3, 18.0 1.69
129SNZOF1 m 10.7 3.73   2   2.63 0.347 8.11, 13.4 -0.12
129SPWKF1 f 10.8 0.0   1   0.0 0.0 10.8, 10.8 0.32
AB6F1 f 12.6 0.0   1   0.0 0.0 12.6, 12.6 0.86
AB6F1 m 13.0 2.07   4 1.04 0.159 10.5, 15.1 0.63
A/J f 13.4 6.4   2   4.52 0.477 8.9, 17.9 1.1
A/J m 9.0 3.08   6 1.26 0.342 6.34, 14.5 -0.68
ANODF1 m 12.0 4.9   7 1.85 0.408 4.77, 20.6 0.31
ANZOF1 f 8.43 0.0   1   0.0 0.0 8.43, 8.43 -0.38
APWKF1 m 9.12 0.0   1   0.0 0.0 9.12, 9.12 -0.64
AWSBF1 m 12.4 0.0   1   0.0 0.0 12.4, 12.4 0.44
B6129SF1/J f 14.0 2.76   2   1.95 0.197 12.1, 16.0 1.28
B6AF1/J f 13.6 0.0   1   0.0 0.0 13.6, 13.6 1.16
B6AF1/J m 8.4 0.0   1   0.0 0.0 8.4, 8.4 -0.88
B6NODF1 f 8.49 0.0   1   0.0 0.0 8.49, 8.49 -0.36
B6NODF1 m 19.2 6.03   2   4.27 0.314 15.0, 23.5 2.68
B6NZOF1 f 15.4 0.0   1   0.0 0.0 15.4, 15.4 1.69
B6NZOF1 m 15.4 0.0   1   0.0 0.0 15.4, 15.4 1.43
B6PWKF1 f 8.77 0.0   1   0.0 0.0 8.77, 8.77 -0.28
C57BL/6J f 7.56 1.81   20 0.404 0.239 4.97, 10.6 -0.64
C57BL/6J m 10.1 2.7   37 0.444 0.267 5.01, 16.4 -0.32
CAST129SF1 m 10.7 1.65   2   1.17 0.155 9.5, 11.8 -0.12
CASTAF1 f 6.06 0.0   1   0.0 0.0 6.06, 6.06 -1.08
CASTAF1 m 11.8 0.184   2   0.13 0.0156 11.6, 11.9 0.24
CASTB6F1 f 7.67 0.0   1   0.0 0.0 7.67, 7.67 -0.6
CASTB6F1 m 8.9 3.47   3 2.0 0.389 5.03, 11.7 -0.72
CAST/EiJ f 5.54 1.47   4 0.734 0.265 3.64, 7.22 -1.24
CAST/EiJ m 9.26 0.735   2   0.52 0.0794 8.74, 9.78 -0.6
CASTNODF1 m 7.59 0.0   1   0.0 0.0 7.59, 7.59 -1.15
CASTNZOF1 f 7.47 4.27   4 2.14 0.571 2.84, 11.8 -0.66
CASTNZOF1 m 8.82 0.0   1   0.0 0.0 8.82, 8.82 -0.74
CASTPWKF1 f 10.7 1.19   5 0.531 0.111 9.3, 12.0 0.3
CASTPWKF1 m 7.16 2.13   6 0.87 0.298 4.24, 9.28 -1.29
CASTWSBF1 f 11.6 2.28   2   1.62 0.196 10.0, 13.3 0.56
NODAF1 f 9.63 0.0   1   0.0 0.0 9.63, 9.63 -0.02
NODB6F1 f 15.2 3.97   3 2.29 0.26 10.7, 17.9 1.63
NODNZOF1 f 16.0 4.58   2   3.24 0.287 12.7, 19.2 1.87
NODNZOF1 m 11.9 5.47   2   3.86 0.459 8.05, 15.8 0.27
NOD/ShiLtJ f 15.4 1.79   3 1.03 0.116 13.5, 17.0 1.69
NOD/ShiLtJ m 10.0 5.06   3 2.92 0.506 6.33, 15.8 -0.35
NZO129SF1 f 15.8 0.0   1   0.0 0.0 15.8, 15.8 1.81
NZOAF1 f 8.8 0.0   1   0.0 0.0 8.8, 8.8 -0.27
NZOB6F1 m 11.2 0.0   1   0.0 0.0 11.2, 11.2 0.04
NZO/HlLtJ m 19.9 0.0   1   0.0 0.0 19.9, 19.9 2.91
NZOWSBF1 f 6.71 2.16   3 1.24 0.321 4.32, 8.5 -0.89
PWK129SF1 f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.51
PWKAF1 f 8.1 0.0   1   0.0 0.0 8.1, 8.1 -0.48
PWKAF1 m 6.19 0.0   1   0.0 0.0 6.19, 6.19 -1.61
PWKNODF1 f 11.1 0.0   1   0.0 0.0 11.1, 11.1 0.41
PWK/PhJ f 12.6 1.82   2   1.29 0.144 11.3, 13.9 0.86
PWK/PhJ m 12.4 8.55   4 4.28 0.69 2.43, 23.2 0.44
WSB129SF1 f 6.38 0.0   1   0.0 0.0 6.38, 6.38 -0.99
WSBAF1 f 6.55 0.0   1   0.0 0.0 6.55, 6.55 -0.94
WSBAF1 m 11.0 2.86   2   2.03 0.261 8.94, 13.0 -0.02
WSBB6F1 f 9.48 3.75   2   2.65 0.396 6.82, 12.1 -0.07
WSBB6F1 m 11.4 2.56   3 1.48 0.225 8.82, 13.9 0.11
WSBCASTF1 m 10.9 2.07   3 1.2 0.19 9.23, 13.2 -0.06
WSB/EiJ f 3.43 1.13   2   0.8 0.33 2.63, 4.23 -1.86
WSB/EiJ m 11.9 0.0   1   0.0 0.0 11.9, 11.9 0.27
WSBNODF1 f 6.5 0.0   1   0.0 0.0 6.5, 6.5 -0.95
WSBNODF1 m 9.15 5.49   2   3.88 0.6 5.27, 13.0 -0.63
WSBNZOF1 f 8.85 3.64   6 1.49 0.411 3.79, 12.6 -0.25
WSBNZOF1 m 11.6 3.31   4 1.66 0.286 7.29, 14.4 0.17
WSBPWKF1 f 5.12 0.403   2   0.285 0.0786 4.84, 5.41 -1.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.23 2.1628 11.5214 2.9386
129S1/SvImJ m 9.965 2.1628 14.2564 5.6736
129SB6F1 f 10.855 2.1628 15.1464 6.5636
129SB6F1 m 9.42 2.1628 13.7114 5.1286
A/J f 13.425 2.1628 17.7164 9.1336
A/J m 9.0033 1.2487 11.481 6.5257
C57BL/6J f 7.5605 0.6839 8.9176 6.2034
C57BL/6J m 10.123 0.5028 11.1207 9.1252
CAST/EiJ f 5.5425 1.5293 8.577 2.508
CAST/EiJ m 9.26 2.1628 13.5514 4.9686
CASTPWKF1 f 10.67 1.3679 13.3841 7.9559
CASTPWKF1 m 7.165 1.2487 9.6426 4.6874
NODNZOF1 f 15.96 2.1628 20.2514 11.6686
NODNZOF1 m 11.915 2.1628 16.2064 7.6236
NOD/ShiLtJ f 15.3833 1.7659 18.8873 11.8794
NOD/ShiLtJ m 9.9967 1.7659 13.5006 6.4927
PWK/PhJ f 12.605 2.1628 16.8964 8.3136
PWK/PhJ m 12.3975 1.5293 15.432 9.363
WSBB6F1 f 9.475 2.1628 13.7664 5.1836
WSBB6F1 m 11.4033 1.7659 14.9073 7.8994
WSBNZOF1 f 8.855 1.2487 11.3326 6.3774
WSBNZOF1 m 11.5975 1.5293 14.632 8.563


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.5975 1.5293 11.632 5.563
129SB6F1 both 10.1375 1.5293 13.172 7.103
A/J both 11.2142 1.2487 13.6918 8.7365
C57BL/6J both 8.8417 0.4244 9.6839 7.9996
CAST/EiJ both 7.4013 1.3244 10.0292 4.7733
CASTPWKF1 both 8.9175 0.926 10.755 7.08
NODNZOF1 both 13.9375 1.5293 16.972 10.903
NOD/ShiLtJ both 12.69 1.2487 15.1676 10.2124
PWK/PhJ both 12.5013 1.3244 15.1292 9.8733
WSBB6F1 both 10.4392 1.3961 13.2093 7.6691
WSBNZOF1 both 10.2262 0.9872 12.185 8.2675




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA