Project measure / variable:   Chesler2   carbon_dioxide

ID, description, units MPD:43406   carbon_dioxide   carbon dioxide (blood CO2)   [mmol/L]  
Data set, strains Chesler2   CC diallel w/par   48 strains     sex: both     age: 7-15wks
Procedure metabolic panel
Ontology mappings

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  STRAIN COMPARISON PLOT


  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 21.0 22.5 24.0 — — 22.0 —
A ♀ — — 25.0 — — 25.0 — —
B6 ♀ 25.0 22.0 22.0 — 23.0 25.0 23.0 —
CAST ♀ — 18.0 25.0 15.6 — 23.2 22.8 19.5
NOD ♀ — 25.0 26.0 — 25.0 26.5 — —
NZO ♀ 25.0 22.0 — — — — — 22.3
PWK ♀ 24.0 17.0 — — 18.0 — — —
WSB ♀ 23.0 21.0 16.5 — 20.0 23.0 21.0 16.5

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 25.5 26.0 — 22.5 26.0 — —
A ♀ — 20.5 23.5 — 25.9 — 23.0 22.0
B6 ♀ — 23.0 23.5 — 27.5 28.0 — —
CAST ♀ 23.5 21.5 21.3 23.0 20.0 23.0 20.0 —
NOD ♀ — — — — 26.0 28.0 — —
NZO ♀ — — 32.0 — 20.0 27.0 — —
PWK ♀ — 23.0 — — — — 25.0 —
WSB ♀ — 18.0 22.3 17.3 23.5 23.5 — 14.5

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested35 strains33 strains
Mean of the strain means22.2   mmol/L 23.3   mmol/L
Median of the strain means22.8   mmol/L 23.0   mmol/L
SD of the strain means± 2.94 ± 3.45
Coefficient of variation (CV)0.133 0.148
Min–max range of strain means15.6   –   26.5   mmol/L 14.5   –   32.0   mmol/L
Mean sample size per strain1.8   mice 2.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 74.7002 74.7002 12.3323 0.0007
strain 7 481.6621 68.8089 11.3597 < 0.0001
sex:strain 7 141.1211 20.1602 3.3283 0.0038
Residuals 77 466.4091 6.0573


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page: 1 - 10 / 68 (68)
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
129SAF1 f 21.0 0.0   1   0.0 0.0 21.0, 21.0 -0.39
129SAF1 m 25.5 2.12   2   1.5 0.0832 24.0, 27.0 0.63
129SB6F1 f 22.5 0.707   2   0.5 0.0314 22.0, 23.0 0.12
129SB6F1 m 26.0 1.41   2   1.0 0.0544 25.0, 27.0 0.78
129SCASTF1 f 24.0 1.41   2   1.0 0.0589 23.0, 25.0 0.63
129SNODF1 m 22.5 2.12   2   1.5 0.0943 21.0, 24.0 -0.24
129SNZOF1 m 26.0 1.41   2   1.0 0.0544 25.0, 27.0 0.78
129SPWKF1 f 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.05
AB6F1 f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.97
AB6F1 m 23.5 3.87   4 1.94 0.165 19.0, 28.0 0.05
A/J m 20.5 1.29   4 0.645 0.063 19.0, 22.0 -0.82
ANODF1 m 25.9 2.48   7 0.937 0.0959 24.0, 31.0 0.75
ANZOF1 f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.97
APWKF1 m 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.09
AWSBF1 m 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.38
B6129SF1/J f 25.0 0.0   2   0.0 0.0 25.0, 25.0 0.97
B6AF1/J f 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.05
B6AF1/J m 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.09
B6NODF1 f 23.0 0.0   1   0.0 0.0 23.0, 23.0 0.29
B6NODF1 m 27.5 0.707   2   0.5 0.0257 27.0, 28.0 1.21
B6NZOF1 f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.97
B6NZOF1 m 28.0 0.0   1   0.0 0.0 28.0, 28.0 1.36
B6PWKF1 f 23.0 0.0   1   0.0 0.0 23.0, 23.0 0.29
C57BL/6J f 22.0 1.85   15 0.478 0.0842 18.0, 24.0 -0.05
C57BL/6J m 23.5 2.0   33 0.348 0.0852 19.0, 28.0 0.05
CAST129SF1 m 23.5 0.707   2   0.5 0.0301 23.0, 24.0 0.05
CASTAF1 f 18.0 0.0   1   0.0 0.0 18.0, 18.0 -1.41
CASTAF1 m 21.5 2.12   2   1.5 0.0987 20.0, 23.0 -0.53
CASTB6F1 f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.97
CASTB6F1 m 21.3 2.52   3 1.45 0.118 19.0, 24.0 -0.58
CAST/EiJ f 15.6 4.34   5 1.94 0.278 10.0, 22.0 -2.23
CAST/EiJ m 23.0 2.83   2   2.0 0.123 21.0, 25.0 -0.09
CASTNODF1 m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.96
CASTNZOF1 f 23.2 0.957   4 0.479 0.0412 22.0, 24.0 0.36
CASTNZOF1 m 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.09
CASTPWKF1 f 22.8 2.77   5 1.24 0.122 20.0, 26.0 0.22
CASTPWKF1 m 20.0 2.53   6 1.03 0.126 17.0, 23.0 -0.96
CASTWSBF1 f 19.5 0.707   2   0.5 0.0363 19.0, 20.0 -0.9
NODAF1 f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.97
NODB6F1 f 26.0 1.0   3 0.577 0.0385 25.0, 27.0 1.31
NODNZOF1 f 26.5 0.707   2   0.5 0.0267 26.0, 27.0 1.48
NODNZOF1 m 28.0 1.41   2   1.0 0.0505 27.0, 29.0 1.36
NOD/ShiLtJ f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.97
NOD/ShiLtJ m 26.0 0.0   1   0.0 0.0 26.0, 26.0 0.78
NZO129SF1 f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.97
NZOAF1 f 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.05
NZOB6F1 m 32.0 0.0   1   0.0 0.0 32.0, 32.0 2.52
NZO/HlLtJ m 27.0 0.0   1   0.0 0.0 27.0, 27.0 1.07
NZONODF1 m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.96
NZOWSBF1 f 22.3 0.577   3 0.333 0.0259 22.0, 23.0 0.05
PWK129SF1 f 24.0 0.0   1   0.0 0.0 24.0, 24.0 0.63
PWKAF1 f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -1.75
PWKAF1 m 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.09
PWKNODF1 f 18.0 0.0   1   0.0 0.0 18.0, 18.0 -1.41
PWK/PhJ m 25.0 2.83   2   2.0 0.113 23.0, 27.0 0.49
WSB129SF1 f 23.0 0.0   1   0.0 0.0 23.0, 23.0 0.29
WSBAF1 f 21.0 0.0   1   0.0 0.0 21.0, 21.0 -0.39
WSBAF1 m 18.0 1.41   2   1.0 0.0786 17.0, 19.0 -1.54
WSBB6F1 f 16.5 4.95   2   3.5 0.3 13.0, 20.0 -1.92
WSBB6F1 m 22.3 5.51   3 3.18 0.247 16.0, 26.0 -0.29
WSBCASTF1 m 17.3 6.35   3 3.67 0.366 10.0, 21.0 -1.74
WSB/EiJ f 16.5 4.95   2   3.5 0.3 13.0, 20.0 -1.92
WSB/EiJ m 14.5 3.54   2   2.5 0.244 12.0, 17.0 -2.55
WSBNODF1 f 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.73
WSBNODF1 m 23.5 0.707   2   0.5 0.0301 23.0, 24.0 0.05
WSBNZOF1 f 23.0 1.26   6 0.516 0.055 21.0, 24.0 0.29
WSBNZOF1 m 23.5 1.73   4 0.866 0.0737 22.0, 25.0 0.05
WSBPWKF1 f 21.0 1.41   2   1.0 0.0673 20.0, 22.0 -0.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 f 22.5 1.7403 25.9654 19.0346
129SB6F1 m 26.0 1.7403 29.4654 22.5346
C57BL/6J f 22.0 0.6355 23.2654 20.7346
C57BL/6J m 23.4848 0.4284 24.338 22.6317
CAST/EiJ f 15.6 1.1007 17.7917 13.4083
CAST/EiJ m 23.0 1.7403 26.4654 19.5346
CASTPWKF1 f 22.8 1.1007 24.9917 20.6083
CASTPWKF1 m 20.0 1.0048 22.0007 17.9993
NODNZOF1 f 26.5 1.7403 29.9654 23.0346
NODNZOF1 m 28.0 1.7403 31.4654 24.5346
WSBB6F1 f 16.5 1.7403 19.9654 13.0346
WSBB6F1 m 22.3333 1.4209 25.1628 19.5039
WSB/EiJ f 16.5 1.7403 19.9654 13.0346
WSB/EiJ m 14.5 1.7403 17.9654 11.0346
WSBNZOF1 f 23.0 1.0048 25.0007 20.9993
WSBNZOF1 m 23.5 1.2306 25.9504 21.0496


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 both 24.25 1.2306 26.7004 21.7996
C57BL/6J both 22.7424 0.3832 23.5055 21.9794
CAST/EiJ both 19.3 1.0296 21.3501 17.2499
CASTPWKF1 both 21.4 0.7452 22.8838 19.9162
NODNZOF1 both 27.25 1.2306 29.7004 24.7996
WSBB6F1 both 19.4167 1.1234 21.6536 17.1798
WSB/EiJ both 15.5 1.2306 17.9504 13.0496
WSBNZOF1 both 23.25 0.7943 24.8317 21.6683




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA