Project measure / variable:   Threadgill2   GSH_total_Rx300

ID, description, units MPD:39631   GSH_total_Rx300   total glutathione   [µmol/mg]  post-Rx 300 mg/kg  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill2 - total glutathione post-Rx 300 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means8.63   µmol/mg
Median of the strain means9.28   µmol/mg
SD of the strain means± 2.50
Coefficient of variation (CV)0.290
Min–max range of strain means5.06   –   11.3   µmol/mg
Mean sample size per strain5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 125.9192 31.4798 1.6697 0.1964
Residuals 20 377.0608 18.853


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 11.3 3.28   5 1.47 0.289 7.52, 16.1 1.07
C57BL/6J m 9.28 2.73   5 1.22 0.294 6.52, 13.8 0.26
DBA/2J m 5.06 0.766   5 0.343 0.151 4.04, 6.13 -1.43
LP/J m 7.22 4.31   5 1.93 0.597 2.32, 13.1 -0.56
NZW/LacJ m 10.3 7.54   5 3.37 0.735 3.46, 22.9 0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 11.35 1.9418 15.4005 7.2995
C57BL/6J m 9.28 1.9418 13.3305 5.2295
DBA/2J m 5.064 1.9418 9.1145 1.0135
LP/J m 7.224 1.9418 11.2745 3.1735
NZW/LacJ m 10.264 1.9418 14.3145 6.2135




  GWAS USING LINEAR MIXED MODELS