Project measure / variable:   Harrill1   hypertro_pan_trt

ID, description, units MPD:39557   hypertro_pan_trt   hepatocytic hypertrophy, panlobular, diffuse   [score]  isoniazid  
isoniazid study
Data set, strains Harrill1   inbred   34 strains     sex: f     age: 8-10wks
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  STRAIN COMPARISON PLOT
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Harrill1 - hepatocytic hypertrophy, panlobular, diffuse isoniazid



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means0.517   score
Median of the strain means0   score
SD of the strain means± 1.07
Coefficient of variation (CV)2.07
Min–max range of strain means0   –   4.00   score
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 135.5162 4.1066 12.1078 < 0.0001
Residuals 100 33.9167 0.3392


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.5 1.0   4 0.5 2.0 -0.02
A/J f 1.25 0.957   4 0.479 0.766 0.69
AKR/J f 0.0 0.0   4 0.0 0.0 -0.48
BALB/cJ f 0.0 0.0   4 0.0 0.0 -0.48
BTBR T+ Itpr3tf/J f 0.0 0.0   4 0.0 0.0 -0.48
BUB/BnJ f 0.0 0.0   4 0.0 0.0 -0.48
C3H/HeJ f 0.0 0.0   4 0.0 0.0 -0.48
C57BL/6J f 0.0 0.0   4 0.0 0.0 -0.48
C57BLKS/J f 0.0 0.0   4 0.0 0.0 -0.48
C57BR/cdJ f 0.0 0.0   4 0.0 0.0 -0.48
C58/J f 0.0 0.0   4 0.0 0.0 -0.48
CBA/J f 0.0 0.0   4 0.0 0.0 -0.48
CE/J f 0.0 0.0   4 0.0 0.0 -0.48
DBA/2J f 0.0 0.0   4 0.0 0.0 -0.48
FVB/NJ f 0.0 0.0   4 0.0 0.0 -0.48
I/LnJ f 0.0 0.0   4 0.0 0.0 -0.48
KK/HlJ f 0.0 0.0   4 0.0 0.0 -0.48
LG/J f 4.0 0.0   3 0.0 0.0 4.0, 4.0 3.26
LP/J f 0.0 0.0   4 0.0 0.0 -0.48
MA/MyJ f 3.0 0.816   4 0.408 0.272 2.0, 4.0 2.32
MRL/MpJ f 0.0 0.0   4 0.0 0.0 -0.48
NOD/ShiLtJ f 2.0 1.15   4 0.577 0.577 1.0, 3.0 1.39
NON/ShiLtJ f 0.0 0.0   4 0.0 0.0 -0.48
NOR/LtJ f 0.0 0.0   4 0.0 0.0 -0.48
NZW/LacJ f 0.0 0.0   4 0.0 0.0 -0.48
P/J f 0.0 0.0   4 0.0 0.0 -0.48
PL/J f 0.0 0.0   4 0.0 0.0 -0.48
PWK/PhJ f 0.0 0.0   4 0.0 0.0 -0.48
RIIIS/J f 1.75 2.06   4 1.03 1.18 1.15
SEA/GnJ f 2.75 0.5   4 0.25 0.182 2.0, 3.0 2.09
SJL/J f 0.0 0.0   4 0.0 0.0 -0.48
SM/J f 0.0 0.0   4 0.0 0.0 -0.48
SWR/J f 0.0 0.0   4 0.0 0.0 -0.48
WSB/EiJ f 2.33 2.08   3 1.2 0.892 1.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5 0.2912 1.0777 -0.0777
A/J f 1.25 0.2912 1.8277 0.6723
AKR/J f 0.0 0.2912 0.5777 -0.5777
BALB/cJ f 0.0 0.2912 0.5777 -0.5777
BTBR T+ Itpr3tf/J f 0.0 0.2912 0.5777 -0.5777
BUB/BnJ f 0.0 0.2912 0.5777 -0.5777
C3H/HeJ f 0.0 0.2912 0.5777 -0.5777
C57BL/6J f 0.0 0.2912 0.5777 -0.5777
C57BLKS/J f 0.0 0.2912 0.5777 -0.5777
C57BR/cdJ f 0.0 0.2912 0.5777 -0.5777
C58/J f 0.0 0.2912 0.5777 -0.5777
CBA/J f 0.0 0.2912 0.5777 -0.5777
CE/J f 0.0 0.2912 0.5777 -0.5777
DBA/2J f 0.0 0.2912 0.5777 -0.5777
FVB/NJ f 0.0 0.2912 0.5777 -0.5777
I/LnJ f 0.0 0.2912 0.5777 -0.5777
KK/HlJ f 0.0 0.2912 0.5777 -0.5777
LG/J f 4.0 0.3362 4.6671 3.3329
LP/J f 0.0 0.2912 0.5777 -0.5777
MA/MyJ f 3.0 0.2912 3.5777 2.4223
MRL/MpJ f 0.0 0.2912 0.5777 -0.5777
NOD/ShiLtJ f 2.0 0.2912 2.5777 1.4223
NON/ShiLtJ f 0.0 0.2912 0.5777 -0.5777
NOR/LtJ f 0.0 0.2912 0.5777 -0.5777
NZW/LacJ f 0.0 0.2912 0.5777 -0.5777
P/J f 0.0 0.2912 0.5777 -0.5777
PL/J f 0.0 0.2912 0.5777 -0.5777
PWK/PhJ f 0.0 0.2912 0.5777 -0.5777
RIIIS/J f 1.75 0.2912 2.3277 1.1723
SEA/GnJ f 2.75 0.2912 3.3277 2.1723
SJL/J f 0.0 0.2912 0.5777 -0.5777
SM/J f 0.0 0.2912 0.5777 -0.5777
SWR/J f 0.0 0.2912 0.5777 -0.5777
WSB/EiJ f 2.3333 0.3362 3.0004 1.6662




  GWAS USING LINEAR MIXED MODELS