Project measure / variable:   Harrill1   microvesic_multi_trt

ID, description, units MPD:39547   microvesic_multi_trt   hepatocytic cytoplasmic, microvesiculation, multifocal   [score]  isoniazid  
isoniazid study
Data set, strains Harrill1   inbred   34 strains     sex: f     age: 8-10wks
Procedure histopathology
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  STRAIN COMPARISON PLOT
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Harrill1 - hepatocytic cytoplasmic, microvesiculation, multifocal isoniazid



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means0.103   score
Median of the strain means0   score
SD of the strain means± 0.436
Coefficient of variation (CV)4.23
Min–max range of strain means0   –   2.50   score
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 25.0373 0.7587 13.7947 < 0.0001
Residuals 100 5.5 0.055


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0 0.0   4 0.0 0.0 -0.24
A/J f 0.0 0.0   4 0.0 0.0 -0.24
AKR/J f 0.0 0.0   4 0.0 0.0 -0.24
BALB/cJ f 2.5 0.577   4 0.289 0.231 2.0, 3.0 5.5
BTBR T+ Itpr3tf/J f 0.0 0.0   4 0.0 0.0 -0.24
BUB/BnJ f 0.0 0.0   4 0.0 0.0 -0.24
C3H/HeJ f 0.25 0.5   4 0.25 2.0 0.34
C57BL/6J f 0.0 0.0   4 0.0 0.0 -0.24
C57BLKS/J f 0.0 0.0   4 0.0 0.0 -0.24
C57BR/cdJ f 0.0 0.0   4 0.0 0.0 -0.24
C58/J f 0.25 0.5   4 0.25 2.0 0.34
CBA/J f 0.0 0.0   4 0.0 0.0 -0.24
CE/J f 0.0 0.0   4 0.0 0.0 -0.24
DBA/2J f 0.0 0.0   4 0.0 0.0 -0.24
FVB/NJ f 0.0 0.0   4 0.0 0.0 -0.24
I/LnJ f 0.0 0.0   4 0.0 0.0 -0.24
KK/HlJ f 0.0 0.0   4 0.0 0.0 -0.24
LG/J f 0.0 0.0   3 0.0 0.0 -0.24
LP/J f 0.0 0.0   4 0.0 0.0 -0.24
MA/MyJ f 0.0 0.0   4 0.0 0.0 -0.24
MRL/MpJ f 0.0 0.0   4 0.0 0.0 -0.24
NOD/ShiLtJ f 0.0 0.0   4 0.0 0.0 -0.24
NON/ShiLtJ f 0.0 0.0   4 0.0 0.0 -0.24
NOR/LtJ f 0.0 0.0   4 0.0 0.0 -0.24
NZW/LacJ f 0.0 0.0   4 0.0 0.0 -0.24
P/J f 0.0 0.0   4 0.0 0.0 -0.24
PL/J f 0.0 0.0   4 0.0 0.0 -0.24
PWK/PhJ f 0.0 0.0   4 0.0 0.0 -0.24
RIIIS/J f 0.0 0.0   4 0.0 0.0 -0.24
SEA/GnJ f 0.0 0.0   4 0.0 0.0 -0.24
SJL/J f 0.0 0.0   4 0.0 0.0 -0.24
SM/J f 0.0 0.0   4 0.0 0.0 -0.24
SWR/J f 0.5 1.0   4 0.5 2.0 0.91
WSB/EiJ f 0.0 0.0   3 0.0 0.0 -0.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0 0.1173 0.2326 -0.2326
A/J f 0.0 0.1173 0.2326 -0.2326
AKR/J f 0.0 0.1173 0.2326 -0.2326
BALB/cJ f 2.5 0.1173 2.7326 2.2674
BTBR T+ Itpr3tf/J f 0.0 0.1173 0.2326 -0.2326
BUB/BnJ f 0.0 0.1173 0.2326 -0.2326
C3H/HeJ f 0.25 0.1173 0.4826 0.0174
C57BL/6J f 0.0 0.1173 0.2326 -0.2326
C57BLKS/J f 0.0 0.1173 0.2326 -0.2326
C57BR/cdJ f 0.0 0.1173 0.2326 -0.2326
C58/J f 0.25 0.1173 0.4826 0.0174
CBA/J f 0.0 0.1173 0.2326 -0.2326
CE/J f 0.0 0.1173 0.2326 -0.2326
DBA/2J f 0.0 0.1173 0.2326 -0.2326
FVB/NJ f 0.0 0.1173 0.2326 -0.2326
I/LnJ f 0.0 0.1173 0.2326 -0.2326
KK/HlJ f 0.0 0.1173 0.2326 -0.2326
LG/J f 0.0 0.1354 0.2686 -0.2686
LP/J f 0.0 0.1173 0.2326 -0.2326
MA/MyJ f 0.0 0.1173 0.2326 -0.2326
MRL/MpJ f 0.0 0.1173 0.2326 -0.2326
NOD/ShiLtJ f 0.0 0.1173 0.2326 -0.2326
NON/ShiLtJ f 0.0 0.1173 0.2326 -0.2326
NOR/LtJ f 0.0 0.1173 0.2326 -0.2326
NZW/LacJ f 0.0 0.1173 0.2326 -0.2326
P/J f 0.0 0.1173 0.2326 -0.2326
PL/J f 0.0 0.1173 0.2326 -0.2326
PWK/PhJ f 0.0 0.1173 0.2326 -0.2326
RIIIS/J f 0.0 0.1173 0.2326 -0.2326
SEA/GnJ f 0.0 0.1173 0.2326 -0.2326
SJL/J f 0.0 0.1173 0.2326 -0.2326
SM/J f 0.0 0.1173 0.2326 -0.2326
SWR/J f 0.5 0.1173 0.7326 0.2674
WSB/EiJ f 0.0 0.1354 0.2686 -0.2686




  GWAS USING LINEAR MIXED MODELS