Project measure / variable:   Crowley1   latency_d120

ID, description, units MPD:39445   latency_d120   latency to move four paws, extrapyramidal side effects   [s]  on day 120  
haloperidol study
Data set, strains Crowley1   inbred w/CC8   26 strains     sex: m     age: 9-28wks
Procedure inclined screen test
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  STRAIN COMPARISON PLOT
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Crowley1 - latency to move four paws, extrapyramidal side effects on day 120



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested26 strains
Mean of the strain means30.8   s
Median of the strain means10.1   s
SD of the strain means± 47.8
Coefficient of variation (CV)1.55
Min–max range of strain means0.200   –   164   s
Mean sample size per strain5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 25 320686.4119 12827.4565 9.1935 < 0.0001
Residuals 122 170223.6083 1395.2755


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 28.6 24.5   8 8.68 0.857 8.0, 70.0 -0.05
A/J m 114.0 75.3   5 33.7 0.661 56.0, 240.0 1.74
AKR/J m 22.6 17.1   5 7.66 0.758 5.0, 50.0 -0.17
BALB/cByJ m 4.25 2.22   4 1.11 0.522 2.0, 7.0 -0.55
BTBR T+ Itpr3tf/J m 4.0 2.2   8 0.779 0.551 -0.56
C3H/HeJ m 3.5 1.73   4 0.866 0.495 2.0, 5.0 -0.57
C57BL/6J m 5.4 2.07   5 0.927 0.384 3.0, 8.0 -0.53
C57BLKS/J m 23.6 18.8   5 8.42 0.798 9.0, 56.0 -0.15
CAST/EiJ m 4.6 2.41   5 1.08 0.524 2.0, 8.0 -0.55
CBA/J m 22.8 15.8   5 7.07 0.694 2.0, 45.0 -0.17
DBA/2J m 10.7 11.9   9 3.98 1.12 4.0, 42.0 -0.42
DDY/JclSidSeyFrkJ m 9.57 8.54   7 3.23 0.892 2.0, 27.0 -0.44
FVB/NJ m 6.0 1.58   5 0.707 0.264 4.0, 8.0 -0.52
KK/HlJ m 9.0 15.3   7 5.77 1.69 -0.46
MA/MyJ m 30.7 30.6   6 12.5 0.999 0.0
MOLF/EiJ m 0.2 0.447   5 0.2 2.24 -0.64
MRL/MpJ m 11.4 5.77   5 2.58 0.506 6.0, 21.0 -0.4
MSM/MsJ m 2.6 2.97   5 1.33 1.14 -0.59
NOD/ShiLtJ m 5.2 1.92   5 0.86 0.37 3.0, 8.0 -0.53
NON/ShiLtJ m 2.29 1.25   7 0.474 0.548 -0.6
NZL/LtJ m 164.0 131.0   7 49.4 0.798 29.0, 300.0 2.78
NZO/HlLtJ m 124.0 62.2   4 31.1 0.502 79.0, 216.0 1.95
NZW/LacJ m 147.0 64.3   5 28.8 0.438 91.0, 245.0 2.43
PWK/PhJ m 11.2 9.26   5 4.14 0.827 -0.41
SJL/J m 30.2 14.9   4 7.45 0.493 18.0, 51.0 -0.01
SM/J m 2.75 2.19   8 0.773 0.796 -0.59


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 28.625 13.2064 54.7684 2.4816
A/J m 114.0 16.7049 147.0691 80.9309
AKR/J m 22.6 16.7049 55.6691 0.0
BALB/cByJ m 4.25 18.6767 41.2224 0.0
BTBR T+ Itpr3tf/J m 4.0 13.2064 30.1434 0.0
C3H/HeJ m 3.5 18.6767 40.4724 0.0
C57BL/6J m 5.4 16.7049 38.4691 0.0
C57BLKS/J m 23.6 16.7049 56.6691 0.0
CAST/EiJ m 4.6 16.7049 37.6691 0.0
CBA/J m 22.8 16.7049 55.8691 0.0
DBA/2J m 10.6667 12.4511 35.3149 0.0
DDY/JclSidSeyFrkJ m 9.5714 14.1183 37.5199 0.0
FVB/NJ m 6.0 16.7049 39.0691 0.0
KK/HlJ m 9.0 14.1183 36.9485 0.0
MA/MyJ m 30.6667 15.2495 60.8545 0.4788
MOLF/EiJ m 0.2 16.7049 33.2691 0.0
MRL/MpJ m 11.4 16.7049 44.4691 0.0
MSM/MsJ m 2.6 16.7049 35.6691 0.0
NOD/ShiLtJ m 5.2 16.7049 38.2691 0.0
NON/ShiLtJ m 2.2857 14.1183 30.2342 0.0
NZL/LtJ m 163.8571 14.1183 191.8056 135.9087
NZO/HlLtJ m 124.0 18.6767 160.9724 87.0276
NZW/LacJ m 147.0 16.7049 180.0691 113.9309
PWK/PhJ m 11.2 16.7049 44.2691 0.0
SJL/J m 30.25 18.6767 67.2224 0.0
SM/J m 2.75 13.2064 28.8934 0.0




  GWAS USING LINEAR MIXED MODELS