Project measure / variable:   Crowley1   latency_d60

ID, description, units MPD:39411   latency_d60   latency to move four paws, extrapyramidal side effects   [s]  on day 60  
haloperidol study
Data set, strains Crowley1   inbred w/CC8   27 strains     sex: m     age: 9-28wks
Procedure inclined screen test
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  STRAIN COMPARISON PLOT
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Crowley1 - latency to move four paws, extrapyramidal side effects on day 60



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested27 strains
Mean of the strain means34.4   s
Median of the strain means8.25   s
SD of the strain means± 61.7
Coefficient of variation (CV)1.79
Min–max range of strain means2.20   –   241   s
Mean sample size per strain5.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 26 621175.0537 23891.3482 20.5716 < 0.0001
Residuals 131 152140.1615 1161.3753


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 19.2 6.61   8 2.34 0.343 12.0, 27.0 -0.25
A/J m 175.0 128.0   5 57.0 0.727 12.0, 300.0 2.28
AKR/J m 20.4 22.7   5 10.2 1.11 9.0, 61.0 -0.23
BALB/cByJ m 8.25 4.43   4 2.21 0.536 4.0, 13.0 -0.42
BTBR T+ Itpr3tf/J m 4.62 2.2   8 0.778 0.476 1.0, 8.0 -0.48
C3H/HeJ m 19.2 14.3   5 6.38 0.743 7.0, 40.0 -0.25
C57BL/6J m 6.4 2.07   5 0.927 0.324 3.0, 8.0 -0.45
C57BLKS/J m 14.0 12.5   5 5.6 0.895 1.0, 31.0 -0.33
CAST/EiJ m 2.2 1.64   5 0.735 0.747 1.0, 5.0 -0.52
CBA/J m 15.8 11.8   5 5.27 0.745 1.0, 30.0 -0.3
DBA/2J m 7.78 8.98   9 2.99 1.15 1.0, 30.0 -0.43
DDY/JclSidSeyFrkJ m 7.86 4.71   7 1.78 0.599 3.0, 17.0 -0.43
FVB/NJ m 3.0 0.707   5 0.316 0.236 2.0, 4.0 -0.51
KK/HlJ m 32.9 43.4   7 16.4 1.32 3.0, 123.0 -0.02
MA/MyJ m 13.3 14.8   6 6.04 1.11 5.0, 43.0 -0.34
MOLF/EiJ m 5.2 2.59   5 1.16 0.498 2.0, 8.0 -0.47
MRL/MpJ m 10.0 4.47   5 2.0 0.447 4.0, 16.0 -0.4
MSM/MsJ m 5.17 2.56   6 1.05 0.496 2.0, 8.0 -0.47
NOD/ShiLtJ m 4.0 2.0   5 0.894 0.5 2.0, 7.0 -0.49
NON/ShiLtJ m 4.62 1.51   8 0.532 0.326 2.0, 7.0 -0.48
NZL/LtJ m 241.0 81.0   8 28.6 0.336 84.0, 302.0 3.35
NZO/HlLtJ m 163.0 79.5   4 39.7 0.488 79.0, 263.0 2.08
NZW/LacJ m 108.0 26.1   5 11.7 0.243 81.0, 141.0 1.19
PWK/PhJ m 4.2 1.92   5 0.86 0.458 2.0, 7.0 -0.49
SJL/J m 27.0 19.9   5 8.91 0.737 6.0, 49.0 -0.12
SM/J m 4.88 2.7   8 0.953 0.553 1.0, 9.0 -0.48
WSB/EiJ m 2.4 1.67   5 0.748 0.697 1.0, 5.0 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 19.25 12.0487 43.0853 0.0
A/J m 175.4 15.2406 205.5495 145.2505
AKR/J m 20.4 15.2406 50.5495 0.0
BALB/cByJ m 8.25 17.0395 41.9582 0.0
BTBR T+ Itpr3tf/J m 4.625 12.0487 28.4603 0.0
C3H/HeJ m 19.2 15.2406 49.3495 0.0
C57BL/6J m 6.4 15.2406 36.5495 0.0
C57BLKS/J m 14.0 15.2406 44.1495 0.0
CAST/EiJ m 2.2 15.2406 32.3495 0.0
CBA/J m 15.8 15.2406 45.9495 0.0
DBA/2J m 7.7778 11.3597 30.2499 0.0
DDY/JclSidSeyFrkJ m 7.8571 12.8806 33.3381 0.0
FVB/NJ m 3.0 15.2406 33.1495 0.0
KK/HlJ m 32.8571 12.8806 58.3381 7.3762
MA/MyJ m 13.3333 13.9127 40.8559 0.0
MOLF/EiJ m 5.2 15.2406 35.3495 0.0
MRL/MpJ m 10.0 15.2406 40.1495 0.0
MSM/MsJ m 5.1667 13.9127 32.6893 0.0
NOD/ShiLtJ m 4.0 15.2406 34.1495 0.0
NON/ShiLtJ m 4.625 12.0487 28.4603 0.0
NZL/LtJ m 241.25 12.0487 265.0853 217.4147
NZO/HlLtJ m 162.75 17.0395 196.4582 129.0418
NZW/LacJ m 107.8 15.2406 137.9495 77.6505
PWK/PhJ m 4.2 15.2406 34.3495 0.0
SJL/J m 27.0 15.2406 57.1495 0.0
SM/J m 4.875 12.0487 28.7103 0.0
WSB/EiJ m 2.4 15.2406 32.5495 0.0




  GWAS USING LINEAR MIXED MODELS