Project measure / variable:   Crowley1   latency_d30

ID, description, units MPD:39410   latency_d30   latency to move four paws, extrapyramidal side effects   [s]  on day 30  
haloperidol study
Data set, strains Crowley1   inbred w/CC8   27 strains     sex: m     age: 9-28wks
Procedure inclined screen test
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  STRAIN COMPARISON PLOT
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Crowley1 - latency to move four paws, extrapyramidal side effects on day 30



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested27 strains
Mean of the strain means43.6   s
Median of the strain means9.71   s
SD of the strain means± 67.6
Coefficient of variation (CV)1.55
Min–max range of strain means2.75   –   234   s
Mean sample size per strain5.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 26 688778.6078 26491.4849 22.6555 < 0.0001
Residuals 132 154350.1595 1169.3194


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 28.9 22.6   8 8.0 0.784 8.0, 78.0 -0.22
A/J m 234.0 74.8   5 33.5 0.32 128.0, 300.0 2.81
AKR/J m 28.0 25.0   5 11.2 0.892 10.0, 70.0 -0.23
BALB/cByJ m 4.2 2.28   5 1.02 0.543 2.0, 7.0 -0.58
BTBR T+ Itpr3tf/J m 3.38 0.916   8 0.324 0.271 2.0, 5.0 -0.6
C3H/HeJ m 15.2 7.95   5 3.56 0.523 9.0, 29.0 -0.42
C57BL/6J m 5.4 2.07   5 0.927 0.384 3.0, 8.0 -0.57
C57BLKS/J m 91.8 39.2   5 17.5 0.427 56.0, 143.0 0.71
CAST/EiJ m 4.6 2.07   5 0.927 0.451 2.0, 7.0 -0.58
CBA/J m 43.6 28.9   5 12.9 0.663 12.0, 87.0 0.0
DBA/2J m 10.0 12.8   9 4.26 1.28 -0.5
DDY/JclSidSeyFrkJ m 9.71 5.68   7 2.15 0.584 2.0, 16.0 -0.5
FVB/NJ m 7.4 6.8   5 3.04 0.92 1.0, 19.0 -0.54
KK/HlJ m 74.6 83.4   7 31.5 1.12 2.0, 194.0 0.46
MA/MyJ m 5.67 7.81   6 3.19 1.38 -0.56
MOLF/EiJ m 5.4 3.65   5 1.63 0.675 1.0, 10.0 -0.57
MRL/MpJ m 9.8 7.09   5 3.17 0.723 4.0, 21.0 -0.5
MSM/MsJ m 5.67 2.88   6 1.17 0.507 1.0, 9.0 -0.56
NOD/ShiLtJ m 5.4 5.03   5 2.25 0.931 1.0, 14.0 -0.57
NON/ShiLtJ m 2.75 1.58   8 0.559 0.575 1.0, 5.0 -0.6
NZL/LtJ m 211.0 83.1   8 29.4 0.393 87.0, 300.0 2.47
NZO/HlLtJ m 171.0 50.6   4 25.3 0.295 98.0, 214.0 1.88
NZW/LacJ m 147.0 55.2   5 24.7 0.376 80.0, 231.0 1.53
PWK/PhJ m 3.0 1.58   5 0.707 0.527 1.0, 5.0 -0.6
SJL/J m 43.2 30.4   5 13.6 0.705 11.0, 81.0 -0.01
SM/J m 4.62 2.83   8 0.999 0.611 1.0, 9.0 -0.58
WSB/EiJ m 3.0 1.58   5 0.707 0.527 1.0, 5.0 -0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 28.875 12.0899 52.79 4.96
A/J m 233.6 15.2926 263.8503 203.3497
AKR/J m 28.0 15.2926 58.2503 0.0
BALB/cByJ m 4.2 15.2926 34.4503 0.0
BTBR T+ Itpr3tf/J m 3.375 12.0899 27.29 0.0
C3H/HeJ m 15.2 15.2926 45.4503 0.0
C57BL/6J m 5.4 15.2926 35.6503 0.0
C57BLKS/J m 91.8 15.2926 122.0503 61.5497
CAST/EiJ m 4.6 15.2926 34.8503 0.0
CBA/J m 43.6 15.2926 73.8503 13.3497
DBA/2J m 10.0 11.3984 32.5472 0.0
DDY/JclSidSeyFrkJ m 9.7143 12.9246 35.2804 0.0
FVB/NJ m 7.4 15.2926 37.6503 0.0
KK/HlJ m 74.5714 12.9246 100.1376 49.0053
MA/MyJ m 5.6667 13.9602 33.2813 0.0
MOLF/EiJ m 5.4 15.2926 35.6503 0.0
MRL/MpJ m 9.8 15.2926 40.0503 0.0
MSM/MsJ m 5.6667 13.9602 33.2813 0.0
NOD/ShiLtJ m 5.4 15.2926 35.6503 0.0
NON/ShiLtJ m 2.75 12.0899 26.665 0.0
NZL/LtJ m 211.375 12.0899 235.29 187.46
NZO/HlLtJ m 171.25 17.0977 205.0709 137.4291
NZW/LacJ m 146.6 15.2926 176.8503 116.3497
PWK/PhJ m 3.0 15.2926 33.2503 0.0
SJL/J m 43.2 15.2926 73.4503 12.9497
SM/J m 4.625 12.0899 28.54 0.0
WSB/EiJ m 3.0 15.2926 33.2503 0.0




  GWAS USING LINEAR MIXED MODELS