Project measure / variable:   Crowley1   latency_d7

ID, description, units MPD:39409   latency_d7   latency to move four paws, extrapyramidal side effects   [s]  on day 7  
haloperidol study
Data set, strains Crowley1   inbred w/CC8   27 strains     sex: m     age: 9-28wks
Procedure inclined screen test
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  STRAIN COMPARISON PLOT
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Crowley1 - latency to move four paws, extrapyramidal side effects on day 7



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested27 strains
Mean of the strain means52.0   s
Median of the strain means16.0   s
SD of the strain means± 72.2
Coefficient of variation (CV)1.39
Min–max range of strain means3.60   –   260   s
Mean sample size per strain5.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 26 786128.9459 30235.7287 21.675 < 0.0001
Residuals 132 184134.1484 1394.9557


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 60.0 39.3   8 13.9 0.654 11.0, 123.0 0.11
A/J m 142.0 67.1   5 30.0 0.473 47.0, 212.0 1.25
AKR/J m 89.6 71.6   5 32.0 0.799 12.0, 200.0 0.52
BALB/cByJ m 3.6 2.7   5 1.21 0.751 1.0, 8.0 -0.67
BTBR T+ Itpr3tf/J m 6.38 2.67   8 0.944 0.419 1.0, 9.0 -0.63
C3H/HeJ m 6.2 2.39   5 1.07 0.385 3.0, 9.0 -0.63
C57BL/6J m 4.4 2.97   5 1.33 0.674 1.0, 8.0 -0.66
C57BLKS/J m 81.4 26.6   5 11.9 0.326 49.0, 103.0 0.41
CAST/EiJ m 4.6 1.52   5 0.678 0.33 3.0, 7.0 -0.66
CBA/J m 49.2 29.4   5 13.2 0.598 11.0, 90.0 -0.04
DBA/2J m 19.1 37.9   9 12.6 1.99 2.0, 120.0 -0.46
DDY/JclSidSeyFrkJ m 56.4 80.7   7 30.5 1.43 2.0, 231.0 0.06
FVB/NJ m 11.4 16.7   5 7.47 1.46 1.0, 41.0 -0.56
KK/HlJ m 53.7 22.4   7 8.47 0.417 23.0, 85.0 0.02
MA/MyJ m 27.7 29.2   6 11.9 1.05 4.0, 73.0 -0.34
MOLF/EiJ m 14.6 5.22   5 2.34 0.358 9.0, 23.0 -0.52
MRL/MpJ m 8.2 3.27   5 1.46 0.399 3.0, 12.0 -0.61
MSM/MsJ m 4.33 4.08   6 1.67 0.942 1.0, 12.0 -0.66
NOD/ShiLtJ m 8.2 8.9   5 3.98 1.09 3.0, 24.0 -0.61
NON/ShiLtJ m 16.0 14.2   8 5.0 0.885 2.0, 45.0 -0.5
NZL/LtJ m 259.0 65.6   8 23.2 0.253 120.0, 300.0 2.87
NZO/HlLtJ m 260.0 57.1   4 28.5 0.219 179.0, 300.0 2.88
NZW/LacJ m 150.0 77.7   5 34.7 0.519 29.0, 231.0 1.36
PWK/PhJ m 12.2 11.0   5 4.91 0.901 3.0, 31.0 -0.55
SJL/J m 45.2 27.1   5 12.1 0.599 22.0, 84.0 -0.09
SM/J m 4.62 3.54   8 1.25 0.766 -0.66
WSB/EiJ m 5.2 1.48   5 0.663 0.285 3.0, 7.0 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 60.0 13.2049 86.1206 33.8794
A/J m 142.0 16.703 175.0402 108.9598
AKR/J m 89.6 16.703 122.6402 56.5598
BALB/cByJ m 3.6 16.703 36.6402 0.0
BTBR T+ Itpr3tf/J m 6.375 13.2049 32.4956 0.0
C3H/HeJ m 6.2 16.703 39.2402 0.0
C57BL/6J m 4.4 16.703 37.4402 0.0
C57BLKS/J m 81.4 16.703 114.4402 48.3598
CAST/EiJ m 4.6 16.703 37.6402 0.0
CBA/J m 49.2 16.703 82.2402 16.1598
DBA/2J m 19.1111 12.4497 43.7379 0.0
DDY/JclSidSeyFrkJ m 56.4286 14.1166 84.3527 28.5045
FVB/NJ m 11.4 16.703 44.4402 0.0
KK/HlJ m 53.7143 14.1166 81.6384 25.7902
MA/MyJ m 27.6667 15.2477 57.8281 0.0
MOLF/EiJ m 14.6 16.703 47.6402 0.0
MRL/MpJ m 8.2 16.703 41.2402 0.0
MSM/MsJ m 4.3333 15.2477 34.4948 0.0
NOD/ShiLtJ m 8.2 16.703 41.2402 0.0
NON/ShiLtJ m 16.0 13.2049 42.1206 0.0
NZL/LtJ m 258.75 13.2049 284.8706 232.6294
NZO/HlLtJ m 260.5 18.6746 297.4401 223.5599
NZW/LacJ m 149.6 16.703 182.6402 116.5598
PWK/PhJ m 12.2 16.703 45.2402 0.0
SJL/J m 45.2 16.703 78.2402 12.1598
SM/J m 4.625 13.2049 30.7456 0.0
WSB/EiJ m 5.2 16.703 38.2402 0.0




  GWAS USING LINEAR MIXED MODELS