Project measure / variable:   Crowley1   latency_d3

ID, description, units MPD:39408   latency_d3   latency to move four paws, extrapyramidal side effects   [s]  on day 3  
haloperidol study
Data set, strains Crowley1   inbred w/CC8   27 strains     sex: m     age: 9-28wks
Procedure inclined screen test
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  STRAIN COMPARISON PLOT
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Crowley1 - latency to move four paws, extrapyramidal side effects on day 3



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested27 strains
Mean of the strain means57.0   s
Median of the strain means9.62   s
SD of the strain means± 73.8
Coefficient of variation (CV)1.30
Min–max range of strain means2.80   –   236   s
Mean sample size per strain5.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 26 860265.8827 33087.1493 14.6956 < 0.0001
Residuals 132 297197.8532 2251.4989


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 70.6 78.4   8 27.7 1.11 6.0, 240.0 0.18
A/J m 149.0 100.0   5 44.8 0.672 23.0, 300.0 1.25
AKR/J m 114.0 115.0   5 51.5 1.01 22.0, 300.0 0.77
BALB/cByJ m 2.8 0.837   5 0.374 0.299 2.0, 4.0 -0.73
BTBR T+ Itpr3tf/J m 5.25 2.92   8 1.03 0.555 1.0, 9.0 -0.7
C3H/HeJ m 8.0 3.24   5 1.45 0.405 5.0, 12.0 -0.66
C57BL/6J m 7.0 4.3   5 1.92 0.614 3.0, 14.0 -0.68
C57BLKS/J m 118.0 54.0   5 24.1 0.457 50.0, 170.0 0.83
CAST/EiJ m 8.2 6.02   5 2.69 0.734 2.0, 18.0 -0.66
CBA/J m 31.4 18.9   5 8.44 0.601 12.0, 60.0 -0.35
DBA/2J m 5.78 3.23   9 1.08 0.559 2.0, 12.0 -0.69
DDY/JclSidSeyFrkJ m 29.6 32.1   7 12.2 1.09 4.0, 98.0 -0.37
FVB/NJ m 9.2 6.76   5 3.02 0.735 1.0, 19.0 -0.65
KK/HlJ m 206.0 102.0   7 38.7 0.497 76.0, 300.0 2.02
MA/MyJ m 35.5 23.7   6 9.66 0.666 5.0, 76.0 -0.29
MOLF/EiJ m 67.8 52.7   5 23.6 0.777 8.0, 120.0 0.15
MRL/MpJ m 6.8 6.94   5 3.1 1.02 3.0, 19.0 -0.68
MSM/MsJ m 5.33 3.01   6 1.23 0.565 2.0, 9.0 -0.7
NOD/ShiLtJ m 2.8 1.3   5 0.583 0.466 1.0, 4.0 -0.73
NON/ShiLtJ m 9.62 6.35   8 2.24 0.659 1.0, 21.0 -0.64
NZL/LtJ m 236.0 58.8   8 20.8 0.249 147.0, 300.0 2.43
NZO/HlLtJ m 222.0 73.2   4 36.6 0.33 123.0, 300.0 2.24
NZW/LacJ m 134.0 71.4   5 31.9 0.534 22.0, 209.0 1.04
PWK/PhJ m 7.6 3.05   5 1.36 0.401 4.0, 12.0 -0.67
SJL/J m 37.2 27.3   5 12.2 0.735 5.0, 78.0 -0.27
SM/J m 4.12 2.9   8 1.03 0.703 1.0, 9.0 -0.72
WSB/EiJ m 4.4 2.07   5 0.927 0.471 2.0, 7.0 -0.71


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 70.625 16.7761 103.8098 37.4402
A/J m 149.2 21.2203 191.1758 107.2242
AKR/J m 114.4 21.2203 156.3758 72.4242
BALB/cByJ m 2.8 21.2203 44.7758 0.0
BTBR T+ Itpr3tf/J m 5.25 16.7761 38.4348 0.0
C3H/HeJ m 8.0 21.2203 49.9758 0.0
C57BL/6J m 7.0 21.2203 48.9758 0.0
C57BLKS/J m 118.0 21.2203 159.9758 76.0242
CAST/EiJ m 8.2 21.2203 50.1758 0.0
CBA/J m 31.4 21.2203 73.3758 0.0
DBA/2J m 5.7778 15.8167 37.0647 0.0
DDY/JclSidSeyFrkJ m 29.5714 17.9344 65.0474 0.0
FVB/NJ m 9.2 21.2203 51.1758 0.0
KK/HlJ m 206.0 17.9344 241.476 170.524
MA/MyJ m 35.5 19.3714 73.8185 0.0
MOLF/EiJ m 67.8 21.2203 109.7758 25.8242
MRL/MpJ m 6.8 21.2203 48.7758 0.0
MSM/MsJ m 5.3333 19.3714 43.6518 0.0
NOD/ShiLtJ m 2.8 21.2203 44.7758 0.0
NON/ShiLtJ m 9.625 16.7761 42.8098 0.0
NZL/LtJ m 236.125 16.7761 269.3098 202.9402
NZO/HlLtJ m 221.75 23.725 268.6804 174.8196
NZW/LacJ m 133.8 21.2203 175.7758 91.8242
PWK/PhJ m 7.6 21.2203 49.5758 0.0
SJL/J m 37.2 21.2203 79.1758 0.0
SM/J m 4.125 16.7761 37.3098 0.0
WSB/EiJ m 4.4 21.2203 46.3758 0.0




  GWAS USING LINEAR MIXED MODELS