Project measure / variable:   Gould1   brain_lithium200

ID, description, units MPD:37408   brain_lithium200   brain lithium concentration   [mmol/L]  dose 200 mg/kg  
lithium study
Data set, strains Gould1   inbred   11 strains     sex: m     age: 7-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Gould1 - brain lithium concentration dose 200 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested11 strains
Mean of the strain means0.809   mmol/L
Median of the strain means0.840   mmol/L
SD of the strain means± 0.163
Coefficient of variation (CV)0.201
Min–max range of strain means0.587   –   1.04   mmol/L
Mean sample size per strain7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 10 1.8957 0.1896 8.8144 < 0.0001
Residuals 72 1.5485 0.0215


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 0.82 0.14   8 0.0496 0.171 0.6, 1.0 0.07
A/J m 1.04 0.045   8 0.0159 0.0431 1.0, 1.12 1.42
BALB/cJ m 0.915 0.279   8 0.0987 0.305 0.32, 1.24 0.65
C3H/HeNHsd m 1.02 0.0674   8 0.0238 0.0664 0.92, 1.12 1.3
C57BL/6J m 0.84 0.098   8 0.0346 0.117 0.64, 0.92 0.19
CBA/J m 0.69 0.0793   8 0.028 0.115 0.52, 0.76 -0.73
Crl:CD-1(ICR) m 0.62 0.0829   6 0.0339 0.134 0.48, 0.72 -1.16
DBA/2J m 0.86 0.0641   8 0.0227 0.0746 0.76, 0.96 0.31
FVB/NJ m 0.587 0.0484   6 0.0198 0.0826 0.52, 0.64 -1.36
Hsd:NIHS m 0.6 0.307   7 0.116 0.512 0.2, 1.16 -1.28
NTac:NIHBS m 0.905 0.0978   8 0.0346 0.108 0.76, 1.04 0.59


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 0.82 0.0519 0.9234 0.7166
A/J m 1.045 0.0519 1.1484 0.9416
BALB/cJ m 0.915 0.0519 1.0184 0.8116
C3H/HeNHsd m 1.015 0.0519 1.1184 0.9116
C57BL/6J m 0.84 0.0519 0.9434 0.7366
CBA/J m 0.69 0.0519 0.7934 0.5866
Crl:CD-1(ICR) m 0.62 0.0599 0.7394 0.5006
DBA/2J m 0.86 0.0519 0.9634 0.7566
FVB/NJ m 0.5867 0.0599 0.706 0.4673
Hsd:NIHS m 0.6 0.0554 0.7105 0.4895
NTac:NIHBS m 0.905 0.0519 1.0084 0.8016




GWAS analysis not available: At least 12 strains are required