Phenotype measure:   Vulpe1   copper

ID, description, units MPD:36801   copper   copper (Cu) content in liver, dry weight   [µg/g]
Data set, strains Vulpe1   inbred   18 strains     sex: both     age: 8wks
Procedure mineral quantification
Ontology mappings


  STRAIN COMPARISON PLOT
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Vulpe1 - copper (Cu) content in liver, dry weight



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means11.9   µg/g 15.7   µg/g
Median of the strain means12.2   µg/g 14.6   µg/g
SD of the strain means± 1.91 ± 4.07
Coefficient of variation (CV)0.161 0.260
Min–max range of strain means7.93   –   16.9   µg/g 9.16   –   24.3   µg/g
Mean sample size per strain6.5   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 988.5532 988.5532 210.2072 < 0.0001
strain 16 1562.0843 97.6303 20.7602 < 0.0001
sex:strain 16 568.4054 35.5253 7.5542 < 0.0001
Residuals 191 898.2266 4.7028


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.62 1.2   6 0.489 0.124 7.55, 11.1 -1.19
129S1/SvImJ m 13.7 1.28   6 0.522 0.0934 12.5, 15.9 -0.48
A/HeJ f 12.3 1.1   6 0.449 0.0895 10.3, 13.6 0.21
A/HeJ m 13.4 0.784   6 0.32 0.0584 12.4, 14.7 -0.56
A/J f 10.4 2.1   6 0.859 0.202 6.78, 12.6 -0.78
A/J m 13.7 3.38   6 1.38 0.247 9.55, 19.1 -0.48
AKR/J f 9.52 1.01   6 0.413 0.106 8.38, 10.7 -1.24
AKR/J m 9.16 0.855   6 0.349 0.0933 8.47, 10.7 -1.6
B10.D2-Hc0 f 7.93 1.26   6 0.516 0.16 6.03, 9.09 -2.07
B10.D2-Hc0 m 12.1 1.54   6 0.629 0.127 10.7, 15.0 -0.88
BALB/cByJ f 12.5 2.23   6 0.911 0.178 8.31, 14.6 0.31
BALB/cByJ m 16.8 1.01   6 0.413 0.0602 15.0, 18.1 0.28
BALB/cJ f 14.0 0.965   6 0.394 0.0691 13.0, 15.4 1.1
BALB/cJ m 23.6 2.86   6 1.17 0.121 18.0, 25.6 1.95
C3H/HeJ f 11.3 1.08   5 0.485 0.0962 10.4, 12.9 -0.31
C3H/HeJ m 11.0 1.73   6 0.705 0.157 8.23, 13.0 -1.15
C57BL/6J f 12.2 2.15   10 0.679 0.175 9.22, 16.6 0.16
C57BL/6J m 15.5 3.05   6 1.25 0.196 11.8, 20.8 -0.04
CAST/EiJ f 12.2 3.68   11 1.11 0.301 8.4, 18.0 0.16
CAST/EiJ m 24.3 3.42   7 1.29 0.141 19.4, 28.6 2.12
DBA/2J f 11.0 1.19   12 0.345 0.109 8.12, 12.9 -0.47
DBA/2J m 16.8 1.8   12 0.52 0.107 13.5, 19.6 0.28
LG/J f 12.3 1.37   6 0.559 0.111 10.1, 13.6 0.21
LG/J m 15.2 2.9   6 1.18 0.191 12.6, 20.7 -0.11
LP/J f 12.3 1.38   6 0.565 0.112 9.9, 14.1 0.21
LP/J m 14.3 1.78   6 0.728 0.125 11.9, 16.5 -0.33
MRL/MpJ f 11.8 0.356   6 0.145 0.0303 11.5, 12.3 -0.05
MRL/MpJ m 17.1 2.11   6 0.863 0.124 14.5, 20.2 0.35
NZB/BlNJ f 16.9 0.861   6 0.352 0.0509 15.7, 18.3 2.61
NZB/BlNJ m 20.9 3.13   10 0.99 0.15 14.3, 25.6 1.29
NZW/LacJ f 12.8 0.631   6 0.258 0.0495 12.1, 13.9 0.47
SM/J f 12.8 2.16   4 1.08 0.169 10.6, 15.5 0.47
SM/J m 14.6 1.45   6 0.592 0.0994 12.9, 16.7 -0.26
SPRET/EiJ f 12.3 3.89   6 1.59 0.317 9.44, 20.1 0.21
SPRET/EiJ m 14.1 3.34   4 1.67 0.238 11.8, 18.9 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.6217 0.8853 11.3679 7.8754
129S1/SvImJ m 13.6833 0.8853 15.4296 11.9371
A/HeJ f 12.3 0.8853 14.0463 10.5537
A/HeJ m 13.4333 0.8853 15.1796 11.6871
A/J f 10.4067 0.8853 12.1529 8.6604
A/J m 13.6583 0.8853 15.4046 11.9121
AKR/J f 9.5217 0.8853 11.2679 7.7754
AKR/J m 9.165 0.8853 10.9113 7.4187
B10.D2-Hc0 f 7.925 0.8853 9.6713 6.1787
B10.D2-Hc0 m 12.1167 0.8853 13.8629 10.3704
BALB/cByJ f 12.5017 0.8853 14.2479 10.7554
BALB/cByJ m 16.8167 0.8853 18.5629 15.0704
BALB/cJ f 13.9667 0.8853 15.7129 12.2204
BALB/cJ m 23.5667 0.8853 25.3129 21.8204
C3H/HeJ f 11.28 0.9698 13.1929 9.3671
C3H/HeJ m 11.005 0.8853 12.7513 9.2587
C57BL/6J f 12.234 0.6858 13.5866 10.8814
C57BL/6J m 15.5333 0.8853 17.2796 13.7871
CAST/EiJ f 12.24 0.6539 13.5297 10.9503
CAST/EiJ m 24.2571 0.8196 25.8739 22.6404
DBA/2J f 10.99 0.626 12.2248 9.7552
DBA/2J m 16.8 0.626 18.0348 15.5652
LG/J f 12.3333 0.8853 14.0796 10.5871
LG/J m 15.1833 0.8853 16.9296 13.4371
LP/J f 12.3167 0.8853 14.0629 10.5704
LP/J m 14.2667 0.8853 16.0129 12.5204
MRL/MpJ f 11.75 0.8853 13.4963 10.0037
MRL/MpJ m 17.1 0.8853 18.8463 15.3537
NZB/BlNJ f 16.9167 0.8853 18.6629 15.1704
NZB/BlNJ m 20.92 0.6858 22.2726 19.5674
SM/J f 12.8 1.0843 14.9387 10.6613
SM/J m 14.5833 0.8853 16.3296 12.8371
SPRET/EiJ f 12.29 0.8853 14.0363 10.5437
SPRET/EiJ m 14.05 1.0843 16.1887 11.9113


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.6525 0.626 12.8873 10.4177
A/HeJ both 12.8667 0.626 14.1015 11.6319
A/J both 12.0325 0.626 13.2673 10.7977
AKR/J both 9.3433 0.626 10.5781 8.1085
B10.D2-Hc0 both 10.0208 0.626 11.2556 8.786
BALB/cByJ both 14.6592 0.626 15.894 13.4244
BALB/cJ both 18.7667 0.626 20.0015 17.5319
C3H/HeJ both 11.1425 0.6566 12.4376 9.8474
C57BL/6J both 13.8837 0.5599 14.9881 12.7792
CAST/EiJ both 18.2486 0.5242 19.2826 17.2145
DBA/2J both 13.895 0.4427 14.7681 13.0219
LG/J both 13.7583 0.626 14.9931 12.5235
LP/J both 13.2917 0.626 14.5265 12.0569
MRL/MpJ both 14.425 0.626 15.6598 13.1902
NZB/BlNJ both 18.9183 0.5599 20.0228 17.8139
SM/J both 13.6917 0.6999 15.0722 12.3111
SPRET/EiJ both 13.17 0.6999 14.5505 11.7895




  GENOME-WIDE ASSOCIATION (GWAS) STATIC PLOT
Plot generated with EMMA / pyLMM using 132K SNP array. Click on plot to view at larger size.