Project measure / variable:   Rhodes1   DG_neurons_wheel

ID, description, units MPD:34606   DG_neurons_wheel   hippocampus: number of new neurons in dentate gyrus   [n]  with running wheel  
exercise study
Data set, strains Rhodes1   inbred   12 strains     sex: both     age: 15wks
Procedure microscopy
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rhodes1 - hippocampus: number of new neurons in dentate gyrus with running wheel



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains12 strains
Mean of the strain means5028   n 4916   n
Median of the strain means5606   n 4935   n
SD of the strain means± 1718 ± 1809
Coefficient of variation (CV)0.342 0.368
Min–max range of strain means2305   –   7091   n 2102   –   9590   n
Mean sample size per strain4.0   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 107319.6614 107319.6614 0.0216 0.8834
strain 11 210577292.6373 19143390.2398 3.8611 0.0002
sex:strain 11 64478949.618 5861722.6925 1.1823 0.3146
Residuals 72 356972801.9167 4957955.5822


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3262.0 2336.0   4 1168.0 0.716 906.0, 6373.0 -1.03
129S1/SvImJ m 2102.0 993.0   4 497.0 0.473 1004.0, 3395.0 -1.55
AKR/J f 7091.0 2551.0   4 1275.0 0.36 3566.0, 9302.0 1.2
AKR/J m 4968.0 2396.0   4 1198.0 0.482 2497.0, 7303.0 0.03
B6129SF1/J f 6816.0 4009.0   4 2004.0 0.588 3664.0, 12240.0 1.04
B6129SF1/J m 9590.0 5472.0   4 2736.0 0.571 5451.0, 17136.0 2.58
B6D2F1/J f 5961.0 1863.0   4 931.0 0.312 3354.0, 7540.0 0.54
B6D2F1/J m 5182.0 1708.0   4 854.0 0.33 3109.0, 7222.0 0.15
BALB/cByJ f 6838.0 3177.0   4 1588.0 0.465 3696.0, 11261.0 1.05
BALB/cByJ m 4966.0 1937.0   4 969.0 0.39 3362.0, 7728.0 0.03
BTBR T+ Itpr3tf/J f 3662.0 897.0   5 401.0 0.245 2921.0, 5124.0 -0.79
BTBR T+ Itpr3tf/J m 4072.0 1380.0   3 797.0 0.339 3076.0, 5647.0 -0.47
C57BL/10J f 6428.0 2136.0   4 1068.0 0.332 4096.0, 8894.0 0.81
C57BL/10J m 4302.0 2248.0   4 1124.0 0.522 2472.0, 7287.0 -0.34
C57BL/6J f 5952.0 1500.0   4 750.0 0.252 3900.0, 7507.0 0.54
C57BL/6J m 4904.0 1631.0   4 815.0 0.332 2725.0, 6675.0 -0.01
CAST/EiJ f 3678.0 912.0   4 456.0 0.248 2725.0, 4668.0 -0.79
CAST/EiJ m 4568.0 617.0   4 308.0 0.135 3860.0, 5124.0 -0.19
DBA/2J f 2305.0 635.0   4 317.0 0.275 1526.0, 2889.0 -1.58
DBA/2J m 2980.0 1147.0   4 573.0 0.385 1689.0, 4186.0 -1.07
NOD/ShiLtJ f 5261.0 577.0   4 289.0 0.11 4733.0, 6014.0 0.14
NOD/ShiLtJ m 5504.0 3487.0   4 1743.0 0.633 3346.0, 10690.0 0.33
SM/J f 3082.0 900.0   4 450.0 0.292 2195.0, 4178.0 -1.13
SM/J m 5848.0 977.0   4 489.0 0.167 5035.0, 7107.0 0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3262.0 1113.3234 5481.3695 1042.6305
129S1/SvImJ m 2101.5 1113.3234 4320.8695 0.0
AKR/J f 7091.0 1113.3234 9310.3695 4871.6305
AKR/J m 4967.5 1113.3234 7186.8695 2748.1305
B6129SF1/J f 6815.75 1113.3234 9035.1195 4596.3805
B6129SF1/J m 9590.0 1113.3234 11809.3695 7370.6305
B6D2F1/J f 5961.0 1113.3234 8180.3695 3741.6305
B6D2F1/J m 5181.5 1113.3234 7400.8695 2962.1305
BALB/cByJ f 6838.0 1113.3234 9057.3695 4618.6305
BALB/cByJ m 4965.5 1113.3234 7184.8695 2746.1305
BTBR T+ Itpr3tf/J f 3662.0 995.7867 5647.0645 1676.9355
BTBR T+ Itpr3tf/J m 4071.6667 1285.5551 6634.3739 1508.9595
C57BL/10J f 6427.75 1113.3234 8647.1195 4208.3805
C57BL/10J m 4302.25 1113.3234 6521.6195 2082.8805
C57BL/6J f 5952.5 1113.3234 8171.8695 3733.1305
C57BL/6J m 4904.0 1113.3234 7123.3695 2684.6305
CAST/EiJ f 3678.25 1113.3234 5897.6195 1458.8805
CAST/EiJ m 4567.5 1113.3234 6786.8695 2348.1305
DBA/2J f 2305.25 1113.3234 4524.6195 85.8805
DBA/2J m 2980.5 1113.3234 5199.8695 761.1305
NOD/ShiLtJ f 5261.25 1113.3234 7480.6195 3041.8805
NOD/ShiLtJ m 5504.0 1113.3234 7723.3695 3284.6305
SM/J f 3082.25 1113.3234 5301.6195 862.8805
SM/J m 5848.5 1113.3234 8067.8695 3629.1305


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2681.75 787.2385 4251.0813 1112.4187
AKR/J both 6029.25 787.2385 7598.5813 4459.9187
B6129SF1/J both 8202.875 787.2385 9772.2063 6633.5437
B6D2F1/J both 5571.25 787.2385 7140.5813 4001.9187
BALB/cByJ both 5901.75 787.2385 7471.0813 4332.4187
BTBR T+ Itpr3tf/J both 3866.8333 813.0564 5487.6317 2246.035
C57BL/10J both 5365.0 787.2385 6934.3313 3795.6687
C57BL/6J both 5428.25 787.2385 6997.5813 3858.9187
CAST/EiJ both 4122.875 787.2385 5692.2063 2553.5437
DBA/2J both 2642.875 787.2385 4212.2063 1073.5437
NOD/ShiLtJ both 5382.625 787.2385 6951.9563 3813.2937
SM/J both 4465.375 787.2385 6034.7063 2896.0437




  GWAS USING LINEAR MIXED MODELS