Project measure / variable:   Rhodes1   DG_vol_control

ID, description, units MPD:34603   DG_vol_control   hippocampus: volume of dentate gyrus   [mm3]  control  
exercise study
Data set, strains Rhodes1   inbred   12 strains     sex: both     age: 15wks
Procedure microscopy
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rhodes1 - hippocampus: volume of dentate gyrus control



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains12 strains
Mean of the strain means0.388   mm3 0.404   mm3
Median of the strain means0.387   mm3 0.386   mm3
SD of the strain means± 0.0495 ± 0.0654
Coefficient of variation (CV)0.128 0.162
Min–max range of strain means0.317   –   0.480   mm3 0.308   –   0.531   mm3
Mean sample size per strain4.0   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0069 0.0069 1.8372 0.1795
strain 11 0.2704 0.0246 6.5749 < 0.0001
sex:strain 11 0.0256 0.0023 0.6232 0.8033
Residuals 72 0.2692 0.0037


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.394 0.0067   4 0.00335 0.017 0.384, 0.399 0.13
129S1/SvImJ m 0.463 0.137   4 0.0684 0.296 0.318, 0.648 0.9
AKR/J f 0.334 0.0345   4 0.0173 0.103 0.296, 0.378 -1.08
AKR/J m 0.348 0.0295   4 0.0148 0.0848 0.326, 0.389 -0.86
B6129SF1/J f 0.48 0.0721   4 0.0361 0.15 0.388, 0.562 1.87
B6129SF1/J m 0.531 0.109   4 0.0546 0.206 0.422, 0.677 1.93
B6D2F1/J f 0.404 0.067   4 0.0335 0.166 0.308, 0.46 0.33
B6D2F1/J m 0.414 0.0587   4 0.0293 0.142 0.36, 0.491 0.15
BALB/cByJ f 0.398 0.0944   4 0.0472 0.237 0.338, 0.538 0.21
BALB/cByJ m 0.397 0.0782   4 0.0391 0.197 0.3, 0.49 -0.11
BTBR T+ Itpr3tf/J f 0.317 0.0381   4 0.019 0.12 0.275, 0.365 -1.43
BTBR T+ Itpr3tf/J m 0.308 0.0696   4 0.0348 0.226 0.229, 0.39 -1.47
C57BL/10J f 0.349 0.0299   4 0.015 0.0857 0.314, 0.387 -0.78
C57BL/10J m 0.367 0.0356   4 0.0178 0.097 0.328, 0.405 -0.57
C57BL/6J f 0.45 0.0283   4 0.0141 0.0628 0.408, 0.468 1.26
C57BL/6J m 0.508 0.0226   4 0.0113 0.0444 0.481, 0.536 1.58
CAST/EiJ f 0.338 0.0476   4 0.0238 0.141 0.293, 0.405 -1.0
CAST/EiJ m 0.373 0.0569   4 0.0285 0.153 0.315, 0.451 -0.48
DBA/2J f 0.379 0.0376   4 0.0188 0.0993 0.328, 0.419 -0.18
DBA/2J m 0.372 0.0351   4 0.0176 0.0943 0.341, 0.418 -0.5
NOD/ShiLtJ f 0.433 0.0292   4 0.0146 0.0674 0.407, 0.46 0.92
NOD/ShiLtJ m 0.377 0.086   4 0.043 0.228 0.302, 0.481 -0.42
SM/J f 0.376 0.0423   4 0.0212 0.113 0.325, 0.428 -0.24
SM/J m 0.395 0.0291   4 0.0145 0.0735 0.372, 0.436 -0.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3938 0.0306 0.4547 0.3328
129S1/SvImJ m 0.4627 0.0306 0.5237 0.4018
AKR/J f 0.3343 0.0306 0.3952 0.2733
AKR/J m 0.3483 0.0306 0.4092 0.2873
B6129SF1/J f 0.4803 0.0306 0.5412 0.4193
B6129SF1/J m 0.5315 0.0306 0.5924 0.4706
B6D2F1/J f 0.4038 0.0306 0.4647 0.3428
B6D2F1/J m 0.4143 0.0306 0.4752 0.3533
BALB/cByJ f 0.398 0.0306 0.4589 0.3371
BALB/cByJ m 0.3973 0.0306 0.4582 0.3363
BTBR T+ Itpr3tf/J f 0.3173 0.0306 0.3782 0.2563
BTBR T+ Itpr3tf/J m 0.3083 0.0306 0.3692 0.2473
C57BL/10J f 0.3492 0.0306 0.4102 0.2883
C57BL/10J m 0.3675 0.0306 0.4284 0.3066
C57BL/6J f 0.4502 0.0306 0.5112 0.3893
C57BL/6J m 0.508 0.0306 0.5689 0.4471
CAST/EiJ f 0.3377 0.0306 0.3987 0.2768
CAST/EiJ m 0.373 0.0306 0.4339 0.3121
DBA/2J f 0.3785 0.0306 0.4394 0.3176
DBA/2J m 0.3725 0.0306 0.4334 0.3116
NOD/ShiLtJ f 0.4332 0.0306 0.4942 0.3723
NOD/ShiLtJ m 0.377 0.0306 0.4379 0.3161
SM/J f 0.3763 0.0306 0.4372 0.3153
SM/J m 0.3953 0.0306 0.4562 0.3343


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4282 0.0216 0.4713 0.3852
AKR/J both 0.3413 0.0216 0.3843 0.2982
B6129SF1/J both 0.5059 0.0216 0.549 0.4628
B6D2F1/J both 0.409 0.0216 0.4521 0.3659
BALB/cByJ both 0.3976 0.0216 0.4407 0.3545
BTBR T+ Itpr3tf/J both 0.3128 0.0216 0.3558 0.2697
C57BL/10J both 0.3584 0.0216 0.4015 0.3153
C57BL/6J both 0.4791 0.0216 0.5222 0.436
CAST/EiJ both 0.3554 0.0216 0.3985 0.3123
DBA/2J both 0.3755 0.0216 0.4186 0.3324
NOD/ShiLtJ both 0.4051 0.0216 0.4482 0.362
SM/J both 0.3858 0.0216 0.4288 0.3427




  GWAS USING LINEAR MIXED MODELS