Project measure / variable:   Rhodes1   activity_wheel

ID, description, units MPD:34602   activity_wheel   locomotor activity   [km/d]  with running wheel  
exercise study
Data set, strains Rhodes1   inbred   12 strains     sex: both     age: 8-15wks
Procedure running wheel monitoring
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  STRAIN COMPARISON PLOT
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Rhodes1 - locomotor activity with running wheel



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains12 strains
Mean of the strain means6.71   km/d 5.36   km/d
Median of the strain means6.62   km/d 4.49   km/d
SD of the strain means± 2.04 ± 2.32
Coefficient of variation (CV)0.304 0.433
Min–max range of strain means3.51   –   10.3   km/d 2.04   –   10.1   km/d
Mean sample size per strain4.0   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 40.8542 40.8542 9.8982 0.0024
strain 11 371.9362 33.8124 8.1921 < 0.0001
sex:strain 11 43.1337 3.9212 0.95 0.499
Residuals 72 297.1752 4.1274


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.51 3.09   4 1.55 0.88 1.27, 8.04 -1.57
129S1/SvImJ m 2.04 0.788   4 0.394 0.387 1.12, 3.04 -1.43
AKR/J f 5.43 1.08   4 0.539 0.198 4.5, 6.55 -0.63
AKR/J m 4.23 0.545   4 0.272 0.129 3.42, 4.55 -0.49
B6129SF1/J f 10.3 2.13   4 1.07 0.206 8.88, 13.5 1.76
B6129SF1/J m 10.1 3.16   4 1.58 0.314 5.53, 12.7 2.05
B6D2F1/J f 7.37 3.16   4 1.58 0.429 5.29, 12.0 0.32
B6D2F1/J m 7.29 1.87   4 0.935 0.256 5.72, 9.42 0.83
BALB/cByJ f 9.08 1.16   4 0.581 0.128 7.42, 10.0 1.16
BALB/cByJ m 4.43 0.462   4 0.231 0.104 3.95, 5.0 -0.4
BTBR T+ Itpr3tf/J f 5.87 1.14   5 0.509 0.194 4.63, 7.25 -0.41
BTBR T+ Itpr3tf/J m 3.41 0.608   3 0.351 0.178 2.71, 3.83 -0.84
C57BL/10J f 5.4 1.99   4 0.994 0.368 2.76, 7.58 -0.64
C57BL/10J m 4.15 2.34   4 1.17 0.564 1.99, 7.41 -0.52
C57BL/6J f 5.73 2.14   4 1.07 0.374 3.9, 8.82 -0.48
C57BL/6J m 3.29 1.31   4 0.655 0.397 2.01, 5.01 -0.89
CAST/EiJ f 8.63 2.18   4 1.09 0.253 5.99, 10.9 0.94
CAST/EiJ m 7.37 2.21   4 1.11 0.3 5.33, 9.7 0.87
DBA/2J f 4.16 2.08   4 1.04 0.5 2.15, 6.66 -1.25
DBA/2J m 4.55 0.442   4 0.221 0.097 4.07, 5.14 -0.35
NOD/ShiLtJ f 7.54 2.0   4 1.0 0.265 4.79, 9.28 0.41
NOD/ShiLtJ m 5.73 0.686   4 0.343 0.12 4.99, 6.4 0.16
SM/J f 7.51 3.76   4 1.88 0.501 2.4, 11.3 0.39
SM/J m 7.67 2.71   4 1.36 0.354 4.97, 10.9 1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.515 1.0158 5.54 1.49
129S1/SvImJ m 2.0375 1.0158 4.0625 0.0125
AKR/J f 5.4325 1.0158 7.4575 3.4075
AKR/J m 4.235 1.0158 6.26 2.21
B6129SF1/J f 10.3325 1.0158 12.3575 8.3075
B6129SF1/J m 10.0575 1.0158 12.0825 8.0325
B6D2F1/J f 7.3725 1.0158 9.3975 5.3475
B6D2F1/J m 7.29 1.0158 9.315 5.265
BALB/cByJ f 9.0825 1.0158 11.1075 7.0575
BALB/cByJ m 4.435 1.0158 6.46 2.41
BTBR T+ Itpr3tf/J f 5.872 0.9086 7.6832 4.0608
BTBR T+ Itpr3tf/J m 3.4067 1.1729 5.7449 1.0684
C57BL/10J f 5.4 1.0158 7.425 3.375
C57BL/10J m 4.1475 1.0158 6.1725 2.1225
C57BL/6J f 5.73 1.0158 7.755 3.705
C57BL/6J m 3.295 1.0158 5.32 1.27
CAST/EiJ f 8.6325 1.0158 10.6575 6.6075
CAST/EiJ m 7.365 1.0158 9.39 5.34
DBA/2J f 4.16 1.0158 6.185 2.135
DBA/2J m 4.5525 1.0158 6.5775 2.5275
NOD/ShiLtJ f 7.545 1.0158 9.57 5.52
NOD/ShiLtJ m 5.73 1.0158 7.755 3.705
SM/J f 7.505 1.0158 9.53 5.48
SM/J m 7.665 1.0158 9.69 5.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.7762 0.7183 4.2081 1.3444
AKR/J both 4.8337 0.7183 6.2656 3.4019
B6129SF1/J both 10.195 0.7183 11.6269 8.7631
B6D2F1/J both 7.3312 0.7183 8.7631 5.8994
BALB/cByJ both 6.7587 0.7183 8.1906 5.3269
BTBR T+ Itpr3tf/J both 4.6393 0.7418 6.1182 3.1605
C57BL/10J both 4.7737 0.7183 6.2056 3.3419
C57BL/6J both 4.5125 0.7183 5.9444 3.0806
CAST/EiJ both 7.9987 0.7183 9.4306 6.5669
DBA/2J both 4.3562 0.7183 5.7881 2.9244
NOD/ShiLtJ both 6.6375 0.7183 8.0694 5.2056
SM/J both 7.585 0.7183 9.0169 6.1531




  GWAS USING LINEAR MIXED MODELS