Project measure / variable:   Shockley1   BW_fat

ID, description, units MPD:33431   BW_fat   body weight   [g]  high-fat diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Shockley1 - body weight high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means21.7   g 27.7   g
Median of the strain means20.8   g 27.0   g
SD of the strain means± 5.69 ± 6.16
Coefficient of variation (CV)0.262 0.222
Min–max range of strain means14.1   –   35.8   g 20.6   –   43.0   g
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 896.4036 896.4036 234.7221 < 0.0001
strain 9 3048.116 338.6796 88.6828 < 0.0001
sex:strain 9 108.7104 12.0789 3.1629 0.0026
Residuals 80 305.52 3.819


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 19.3 2.17   5 0.969 0.112 16.4, 21.5 -0.43
129S1/SvImJ m 28.4 2.18   5 0.974 0.0766 25.1, 30.8 0.11
A/J f 20.1 1.62   5 0.724 0.0803 17.9, 22.0 -0.29
A/J m 22.3 0.978   5 0.437 0.0438 21.2, 23.4 -0.88
BALB/cJ f 22.4 0.814   5 0.364 0.0364 21.0, 23.1 0.12
BALB/cJ m 27.8 0.966   5 0.432 0.0347 26.5, 29.1 0.01
C3H/HeJ f 21.5 3.23   5 1.45 0.15 17.4, 24.2 -0.04
C3H/HeJ m 27.8 1.95   5 0.87 0.07 26.3, 31.2 0.01
C57BL/6J f 18.7 1.43   5 0.638 0.0764 17.1, 20.6 -0.53
C57BL/6J m 25.1 1.16   5 0.52 0.0463 23.2, 25.9 -0.42
DBA/2J f 22.7 0.493   5 0.22 0.0217 21.9, 23.2 0.17
DBA/2J m 25.0 1.67   5 0.746 0.0666 22.6, 26.7 -0.44
I/LnJ f 18.6 0.268   5 0.12 0.0144 18.2, 18.9 -0.55
I/LnJ m 26.1 2.27   5 1.02 0.0871 23.2, 28.4 -0.26
MRL/MpJ-Faslpr/J f 35.8 4.43   5 1.98 0.124 31.3, 43.0 2.47
MRL/MpJ-Faslpr/J m 43.0 2.22   5 0.993 0.0517 40.0, 45.2 2.48
NZB/BlNJ f 24.2 0.607   5 0.271 0.0251 23.5, 24.9 0.43
NZB/BlNJ m 31.0 1.01   5 0.451 0.0325 29.4, 32.0 0.53
SM/J f 14.1 1.88   5 0.841 0.133 12.4, 16.4 -1.34
SM/J m 20.6 2.54   5 1.14 0.124 17.1, 23.5 -1.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 19.26 0.874 20.9992 17.5208
129S1/SvImJ m 28.44 0.874 30.1792 26.7008
A/J f 20.14 0.874 21.8792 18.4008
A/J m 22.32 0.874 24.0592 20.5808
BALB/cJ f 22.36 0.874 24.0992 20.6208
BALB/cJ m 27.84 0.874 29.5792 26.1008
C3H/HeJ f 21.5 0.874 23.2392 19.7608
C3H/HeJ m 27.82 0.874 29.5592 26.0808
C57BL/6J f 18.66 0.874 20.3992 16.9208
C57BL/6J m 25.14 0.874 26.8792 23.4008
DBA/2J f 22.74 0.874 24.4792 21.0008
DBA/2J m 25.04 0.874 26.7792 23.3008
I/LnJ f 18.62 0.874 20.3592 16.8808
I/LnJ m 26.08 0.874 27.8192 24.3408
MRL/MpJ-Faslpr/J f 35.78 0.874 37.5192 34.0408
MRL/MpJ-Faslpr/J m 42.98 0.874 44.7192 41.2408
NZB/BlNJ f 24.16 0.874 25.8992 22.4208
NZB/BlNJ m 31.02 0.874 32.7592 29.2808
SM/J f 14.14 0.874 15.8792 12.4008
SM/J m 20.56 0.874 22.2992 18.8208


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 23.85 0.618 25.0798 22.6202
A/J both 21.23 0.618 22.4598 20.0002
BALB/cJ both 25.1 0.618 26.3298 23.8702
C3H/HeJ both 24.66 0.618 25.8898 23.4302
C57BL/6J both 21.9 0.618 23.1298 20.6702
DBA/2J both 23.89 0.618 25.1198 22.6602
I/LnJ both 22.35 0.618 23.5798 21.1202
MRL/MpJ-Faslpr/J both 39.38 0.618 40.6098 38.1502
NZB/BlNJ both 27.59 0.618 28.8198 26.3602
SM/J both 17.35 0.618 18.5798 16.1202




  GWAS USING LINEAR MIXED MODELS