Project measure / variable:   Shockley1   BW

ID, description, units MPD:33401   BW   body weight   [g]  control diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Shockley1 - body weight control diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means20.3   g 25.4   g
Median of the strain means19.8   g 23.6   g
SD of the strain means± 4.28 ± 5.60
Coefficient of variation (CV)0.211 0.220
Min–max range of strain means14.9   –   30.7   g 19.9   –   39.2   g
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 654.3364 654.3364 181.9395 < 0.0001
strain 9 2080.4676 231.1631 64.2753 < 0.0001
sex:strain 9 156.6516 17.4057 4.8397 < 0.0001
Residuals 80 287.716 3.5964


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 16.3 0.856   5 0.383 0.0524 15.1, 17.2 -0.94
129S1/SvImJ m 21.5 3.08   5 1.38 0.143 18.4, 26.6 -0.7
A/J f 20.6 2.03   5 0.91 0.0988 17.8, 23.2 0.07
A/J m 23.3 2.0   5 0.894 0.0858 19.9, 25.2 -0.38
BALB/cJ f 19.5 0.699   5 0.312 0.0359 18.6, 20.4 -0.19
BALB/cJ m 24.0 2.72   5 1.22 0.113 20.2, 26.8 -0.26
C3H/HeJ f 19.9 1.04   5 0.463 0.0519 18.4, 21.3 -0.1
C3H/HeJ m 27.4 1.15   5 0.516 0.0421 25.6, 28.7 0.35
C57BL/6J f 18.0 1.4   5 0.625 0.0778 16.8, 19.8 -0.54
C57BL/6J m 25.3 1.25   5 0.56 0.0495 23.8, 26.9 -0.02
DBA/2J f 21.9 1.66   5 0.741 0.0758 19.0, 23.3 0.37
DBA/2J m 22.3 0.958   5 0.428 0.043 21.1, 23.2 -0.56
I/LnJ f 19.6 1.4   5 0.625 0.0713 18.0, 21.5 -0.17
I/LnJ m 22.1 1.49   5 0.665 0.0672 19.9, 23.9 -0.59
MRL/MpJ-Faslpr/J f 30.7 3.05   5 1.36 0.0992 26.1, 34.2 2.43
MRL/MpJ-Faslpr/J m 39.2 3.01   5 1.35 0.0768 35.2, 43.5 2.46
NZB/BlNJ f 21.8 1.68   5 0.75 0.077 20.2, 23.6 0.35
NZB/BlNJ m 29.3 2.43   5 1.09 0.0829 26.1, 31.7 0.69
SM/J f 14.9 1.36   5 0.609 0.0911 13.3, 16.4 -1.27
SM/J m 19.9 1.74   5 0.78 0.0875 17.7, 22.2 -0.99


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 16.34 0.8481 18.0278 14.6522
129S1/SvImJ m 21.5 0.8481 23.1878 19.8122
A/J f 20.58 0.8481 22.2678 18.8922
A/J m 23.3 0.8481 24.9878 21.6122
BALB/cJ f 19.46 0.8481 21.1478 17.7722
BALB/cJ m 23.96 0.8481 25.6478 22.2722
C3H/HeJ f 19.94 0.8481 21.6278 18.2522
C3H/HeJ m 27.44 0.8481 29.1278 25.7522
C57BL/6J f 17.96 0.8481 19.6478 16.2722
C57BL/6J m 25.28 0.8481 26.9678 23.5922
DBA/2J f 21.86 0.8481 23.5478 20.1722
DBA/2J m 22.28 0.8481 23.9678 20.5922
I/LnJ f 19.6 0.8481 21.2878 17.9122
I/LnJ m 22.12 0.8481 23.8078 20.4322
MRL/MpJ-Faslpr/J f 30.74 0.8481 32.4278 29.0522
MRL/MpJ-Faslpr/J m 39.22 0.8481 40.9078 37.5322
NZB/BlNJ f 21.78 0.8481 23.4678 20.0922
NZB/BlNJ m 29.32 0.8481 31.0078 27.6322
SM/J f 14.94 0.8481 16.6278 13.2522
SM/J m 19.94 0.8481 21.6278 18.2522


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 18.92 0.5997 20.1134 17.7266
A/J both 21.94 0.5997 23.1334 20.7466
BALB/cJ both 21.71 0.5997 22.9034 20.5166
C3H/HeJ both 23.69 0.5997 24.8834 22.4966
C57BL/6J both 21.62 0.5997 22.8134 20.4266
DBA/2J both 22.07 0.5997 23.2634 20.8766
I/LnJ both 20.86 0.5997 22.0534 19.6666
MRL/MpJ-Faslpr/J both 34.98 0.5997 36.1734 33.7866
NZB/BlNJ both 25.55 0.5997 26.7434 24.3566
SM/J both 17.44 0.5997 18.6334 16.2466




  GWAS USING LINEAR MIXED MODELS