Project measure / variable:   Maurer1   atr_ventr_at


  STRAIN COMPARISON PLOT
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Maurer1 - atria weight to ventricle weight ratio atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means16.6   ratio
Median of the strain means16.5   ratio
SD of the strain means± 2.06
Coefficient of variation (CV)0.124
Min–max range of strain means13.4   –   20.8   ratio
Mean sample size per strain10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 1031.8973 46.9044 13.7019 < 0.0001
Residuals 216 739.4132 3.4232


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 20.8 2.44   13 0.676 0.117 17.6, 25.0 2.02
A/J m 15.6 1.69   10 0.536 0.108 13.3, 18.0 -0.5
AKR/J m 20.7 2.0   9 0.667 0.0966 17.8, 24.0 1.97
BALB/cByJ m 16.0 1.83   16 0.457 0.114 13.3, 20.3 -0.3
BALB/cJ m 14.2 1.61   10 0.509 0.113 11.7, 16.9 -1.18
BTBR T+ Itpr3tf/J m 16.9 1.17   9 0.39 0.0692 14.6, 18.1 0.13
C3H/HeJ m 14.8 1.36   10 0.431 0.0919 12.8, 17.8 -0.88
C3H/HeOuJ m 14.6 1.64   10 0.519 0.112 12.7, 18.4 -0.98
C57BL/6J m 16.2 1.32   9 0.441 0.0817 14.8, 18.8 -0.21
C57BLKS/J m 17.5 1.84   9 0.614 0.105 14.8, 20.0 0.42
C58/J m 18.9 3.37   12 0.972 0.178 12.3, 24.0 1.1
CBA/J m 16.5 1.55   9 0.518 0.0941 13.8, 18.7 -0.06
DBA/2J m 16.8 1.79   10 0.566 0.106 13.7, 18.7 0.08
FVB/NJ m 13.4 1.06   14 0.283 0.079 11.5, 15.0 -1.56
I/LnJ m 14.4 1.02   10 0.321 0.0706 12.6, 15.6 -1.08
KK/HlJ m 17.0 1.38   9 0.46 0.0811 14.1, 18.6 0.18
LP/J m 19.8 2.73   10 0.864 0.138 16.8, 24.6 1.54
NOD/ShiLtJ m 14.6 2.03   10 0.642 0.139 12.2, 19.0 -0.98
NZB/BlNJ m 15.8 1.12   9 0.372 0.0706 14.0, 17.6 -0.4
PL/J m 18.2 1.49   10 0.472 0.0818 16.6, 21.9 0.76
SJL/J m 14.8 1.75   9 0.584 0.118 10.9, 17.4 -0.88
SM/J m 18.2 2.52   11 0.759 0.138 15.0, 23.1 0.76
SWR/J m 16.7 0.979   11 0.295 0.0586 14.7, 17.7 0.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 20.8231 0.5132 21.8345 19.8117
A/J m 15.61 0.5851 16.7632 14.4568
AKR/J m 20.7333 0.6167 21.9489 19.5178
BALB/cByJ m 15.9625 0.4625 16.8742 15.0508
BALB/cJ m 14.19 0.5851 15.3432 13.0368
BTBR T+ Itpr3tf/J m 16.9111 0.6167 18.1267 15.6955
C3H/HeJ m 14.84 0.5851 15.9932 13.6868
C3H/HeOuJ m 14.64 0.5851 15.7932 13.4868
C57BL/6J m 16.2111 0.6167 17.4267 14.9955
C57BLKS/J m 17.4556 0.6167 18.6711 16.24
C58/J m 18.9167 0.5341 19.9694 17.8639
CBA/J m 16.5111 0.6167 17.7267 15.2955
DBA/2J m 16.81 0.5851 17.9632 15.6568
FVB/NJ m 13.4071 0.4945 14.3818 12.4325
I/LnJ m 14.38 0.5851 15.5332 13.2268
KK/HlJ m 17.0222 0.6167 18.2378 15.8066
LP/J m 19.83 0.5851 20.9832 18.6768
NOD/ShiLtJ m 14.6 0.5851 15.7532 13.4468
NZB/BlNJ m 15.7889 0.6167 17.0045 14.5733
PL/J m 18.25 0.5851 19.4032 17.0968
SJL/J m 14.8333 0.6167 16.0489 13.6178
SM/J m 18.2455 0.5579 19.345 17.1459
SWR/J m 16.7091 0.5579 17.8086 15.6096




  GWAS USING LINEAR MIXED MODELS