Project measure / variable:   Maurer1   atria_wt_at

ID, description, units MPD:33279   atria_wt_at   atria weight   [mg]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Maurer1 - atria weight atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means5.81   mg
Median of the strain means5.92   mg
SD of the strain means± 1.05
Coefficient of variation (CV)0.180
Min–max range of strain means4.25   –   7.36   mg
Mean sample size per strain10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 267.3019 12.1501 18.6095 < 0.0001
Residuals 216 141.0257 0.6529


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 4.61 0.787   13 0.218 0.171 3.3, 6.01 -1.15
A/J m 4.25 0.769   10 0.243 0.181 3.2, 5.58 -1.49
AKR/J m 5.56 0.896   9 0.299 0.161 4.76, 7.56 -0.24
BALB/cByJ m 7.36 0.972   16 0.243 0.132 5.2, 9.3 1.48
BALB/cJ m 6.54 0.844   10 0.267 0.129 5.4, 7.88 0.7
BTBR T+ Itpr3tf/J m 7.12 0.883   9 0.294 0.124 5.79, 8.67 1.25
C3H/HeJ m 5.92 0.899   10 0.284 0.152 4.4, 7.4 0.11
C3H/HeOuJ m 5.92 0.705   10 0.223 0.119 4.6, 7.1 0.11
C57BL/6J m 5.22 0.395   9 0.132 0.0757 4.6, 5.7 -0.56
C57BLKS/J m 4.86 0.736   9 0.245 0.151 3.9, 5.98 -0.91
C58/J m 4.61 1.03   12 0.299 0.224 3.3, 6.3 -1.15
CBA/J m 5.39 0.708   9 0.236 0.131 4.7, 6.9 -0.4
DBA/2J m 6.25 0.798   10 0.252 0.128 5.3, 7.9 0.42
FVB/NJ m 7.24 0.734   14 0.196 0.101 6.0, 8.4 1.37
I/LnJ m 6.89 0.633   10 0.2 0.0918 6.0, 7.85 1.03
KK/HlJ m 6.85 0.922   9 0.307 0.135 5.7, 8.92 0.99
LP/J m 4.28 0.792   10 0.251 0.185 2.88, 5.6 -1.46
NOD/ShiLtJ m 6.5 1.14   10 0.36 0.175 4.3, 8.5 0.66
NZB/BlNJ m 7.18 0.593   9 0.198 0.0827 6.4, 8.4 1.31
PL/J m 6.13 0.812   10 0.257 0.132 4.69, 7.5 0.31
SJL/J m 5.88 0.934   9 0.311 0.159 5.0, 8.1 0.07
SM/J m 4.41 0.722   11 0.218 0.164 3.11, 5.88 -1.34
SWR/J m 4.65 0.238   11 0.0717 0.0511 4.4, 5.15 -1.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 4.6077 0.2241 5.0494 4.166
A/J m 4.253 0.2555 4.7566 3.7494
AKR/J m 5.5578 0.2693 6.0886 5.0269
BALB/cByJ m 7.3625 0.202 7.7607 6.9643
BALB/cJ m 6.536 0.2555 7.0396 6.0324
BTBR T+ Itpr3tf/J m 7.1156 0.2693 7.6464 6.5847
C3H/HeJ m 5.92 0.2555 6.4236 5.4164
C3H/HeOuJ m 5.92 0.2555 6.4236 5.4164
C57BL/6J m 5.2233 0.2693 5.7542 4.6925
C57BLKS/J m 4.8611 0.2693 5.392 4.3302
C58/J m 4.6108 0.2333 5.0706 4.1511
CBA/J m 5.3889 0.2693 5.9198 4.858
DBA/2J m 6.25 0.2555 6.7536 5.7464
FVB/NJ m 7.2379 0.216 7.6635 6.8122
I/LnJ m 6.893 0.2555 7.3966 6.3894
KK/HlJ m 6.8478 0.2693 7.3786 6.3169
LP/J m 4.278 0.2555 4.7816 3.7744
NOD/ShiLtJ m 6.495 0.2555 6.9986 5.9914
NZB/BlNJ m 7.1778 0.2693 7.7086 6.6469
PL/J m 6.127 0.2555 6.6306 5.6234
SJL/J m 5.8778 0.2693 6.4086 5.3469
SM/J m 4.4091 0.2436 4.8893 3.9289
SWR/J m 4.6509 0.2436 5.1311 4.1707




  GWAS USING LINEAR MIXED MODELS