Project measure / variable:   Maurer1   QTc_area_ctrl

ID, description, units MPD:33261   QTc_area_ctrl   area of QTc   [ms*mV]  control  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - area of QTc control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means47.8   ms*mV
Median of the strain means47.1   ms*mV
SD of the strain means± 4.47
Coefficient of variation (CV)0.0936
Min–max range of strain means39.8   –   55.5   ms*mV
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 4533.0554 206.048 3.4823 < 0.0001
Residuals 202 11952.2306 59.1695


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 50.7 4.41   13 1.22 0.0869 45.2, 60.0 0.64
A/J m 40.4 9.39   11 2.83 0.232 20.1, 51.6 -1.66
AKR/J m 53.3 4.48   8 1.58 0.0841 48.4, 62.9 1.23
BALB/cByJ m 52.6 3.38   9 1.13 0.0643 48.4, 58.8 1.07
BALB/cJ m 45.7 4.28   10 1.35 0.0936 37.3, 50.5 -0.47
BTBR T+ Itpr3tf/J m 48.7 2.75   10 0.87 0.0565 44.5, 53.4 0.2
C3H/HeJ m 44.9 7.62   10 2.41 0.17 24.2, 51.0 -0.65
C3H/HeOuJ m 49.4 3.79   9 1.26 0.0767 44.7, 56.7 0.35
C57BL/6J m 45.6 3.96   9 1.32 0.0869 38.2, 50.7 -0.5
C57BLKS/J m 46.8 3.08   10 0.973 0.0657 44.5, 55.0 -0.23
C58/J m 52.7 5.84   12 1.68 0.111 46.9, 65.5 1.09
CBA/J m 45.5 8.42   8 2.98 0.185 29.3, 58.2 -0.52
DBA/2J m 48.8 11.6   6 4.74 0.238 32.3, 59.2 0.22
FVB/NJ m 47.1 4.51   12 1.3 0.0957 36.4, 52.7 -0.16
I/LnJ m 50.8 25.8   10 8.17 0.508 14.1, 99.9 0.67
KK/HlJ m 55.3 2.8   10 0.886 0.0507 49.0, 58.2 1.67
LP/J m 44.4 2.56   8 0.904 0.0577 39.9, 47.8 -0.76
NOD/ShiLtJ m 42.7 3.48   9 1.16 0.0815 37.2, 47.2 -1.14
NZB/BlNJ m 46.5 2.47   8 0.872 0.053 41.4, 48.5 -0.29
PL/J m 41.9 5.95   10 1.88 0.142 30.4, 53.0 -1.32
SJL/J m 39.8 2.29   9 0.763 0.0575 36.0, 43.3 -1.79
SM/J m 55.5 6.81   14 1.82 0.123 48.6, 69.7 1.72
SWR/J m 50.7 7.68   10 2.43 0.151 42.0, 62.9 0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 50.7154 2.1334 54.922 46.5087
A/J m 40.4091 2.3193 44.9822 35.836
AKR/J m 53.2875 2.7196 58.6499 47.9251
BALB/cByJ m 52.5889 2.5641 57.6446 47.5331
BALB/cJ m 45.68 2.4325 50.4763 40.8837
BTBR T+ Itpr3tf/J m 48.67 2.4325 53.4663 43.8737
C3H/HeJ m 44.88 2.4325 49.6763 40.0837
C3H/HeOuJ m 49.4 2.5641 54.4557 44.3443
C57BL/6J m 45.5667 2.5641 50.6224 40.5109
C57BLKS/J m 46.83 2.4325 51.6263 42.0337
C58/J m 52.7 2.2205 57.0784 48.3216
CBA/J m 45.525 2.7196 50.8874 40.1626
DBA/2J m 48.75 3.1403 54.942 42.558
FVB/NJ m 47.0833 2.2205 51.4617 42.7049
I/LnJ m 50.83 2.4325 55.6263 46.0337
KK/HlJ m 55.28 2.4325 60.0763 50.4837
LP/J m 44.35 2.7196 49.7124 38.9876
NOD/ShiLtJ m 42.7333 2.5641 47.7891 37.6776
NZB/BlNJ m 46.475 2.7196 51.8374 41.1126
PL/J m 41.93 2.4325 46.7263 37.1337
SJL/J m 39.8 2.5641 44.8557 34.7443
SM/J m 55.5071 2.0558 59.5608 51.4535
SWR/J m 50.74 2.4325 55.5363 45.9437




  GWAS USING LINEAR MIXED MODELS