Project measure / variable:   Maurer1   ST_at

ID, description, units MPD:33250   ST_at   interval ST   [ms]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval ST atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means44.4   ms
Median of the strain means42.5   ms
SD of the strain means± 6.39
Coefficient of variation (CV)0.144
Min–max range of strain means36.8   –   65.3   ms
Mean sample size per strain9.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 7340.7854 333.6721 4.5675 < 0.0001
Residuals 195 14245.3759 73.0532


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 42.5 11.4   13 3.17 0.269 20.6, 64.7 -0.3
A/J m 38.9 4.27   10 1.35 0.11 32.9, 47.5 -0.86
AKR/J m 49.1 5.72   7 2.16 0.116 42.0, 60.1 0.73
BALB/cByJ m 42.4 9.66   8 3.42 0.228 26.0, 54.7 -0.31
BALB/cJ m 42.2 5.9   10 1.86 0.14 33.2, 50.6 -0.35
BTBR T+ Itpr3tf/J m 43.3 3.18   9 1.06 0.0735 38.4, 48.3 -0.17
C3H/HeJ m 40.5 6.06   8 2.14 0.15 28.4, 47.0 -0.61
C3H/HeOuJ m 50.5 3.6   9 1.2 0.0712 45.9, 56.7 0.95
C57BL/6J m 39.7 2.38   9 0.794 0.06 35.0, 42.6 -0.74
C57BLKS/J m 50.5 7.46   9 2.49 0.148 42.7, 64.9 0.95
C58/J m 42.4 4.56   12 1.32 0.108 35.0, 49.4 -0.31
CBA/J m 40.1 11.4   6 4.65 0.284 29.6, 61.0 -0.67
DBA/2J m 55.4 15.8   6 6.45 0.285 29.8, 74.5 1.72
FVB/NJ m 42.2 4.03   14 1.08 0.0956 36.9, 49.4 -0.35
I/LnJ m 65.3 29.8   8 10.5 0.457 44.4, 128.0 3.27
KK/HlJ m 42.6 4.13   9 1.38 0.0971 36.1, 51.0 -0.28
LP/J m 36.8 3.63   10 1.15 0.0988 29.5, 43.3 -1.19
NOD/ShiLtJ m 43.3 2.98   10 0.941 0.0687 37.6, 47.6 -0.17
NZB/BlNJ m 43.5 8.17   9 2.72 0.188 33.5, 59.9 -0.14
PL/J m 41.8 6.13   10 1.94 0.147 33.4, 53.7 -0.41
SJL/J m 36.8 3.4   9 1.13 0.0924 33.2, 41.1 -1.19
SM/J m 47.4 3.1   12 0.894 0.0653 42.3, 52.7 0.47
SWR/J m 44.3 6.72   11 2.03 0.152 34.7, 58.2 -0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 42.4615 2.3705 47.1367 37.7863
A/J m 38.87 2.7028 44.2005 33.5395
AKR/J m 49.1286 3.2305 55.4998 42.7574
BALB/cByJ m 42.4375 3.0219 48.3972 36.4778
BALB/cJ m 42.2 2.7028 47.5305 36.8695
BTBR T+ Itpr3tf/J m 43.3444 2.849 48.9633 37.7256
C3H/HeJ m 40.45 3.0219 46.4097 34.4903
C3H/HeOuJ m 50.5111 2.849 56.13 44.8922
C57BL/6J m 39.7111 2.849 45.33 34.0922
C57BLKS/J m 50.5111 2.849 56.13 44.8922
C58/J m 42.3583 2.4673 47.2244 37.4922
CBA/J m 40.15 3.4893 47.0317 33.2683
DBA/2J m 55.3833 3.4893 62.265 48.5016
FVB/NJ m 42.2143 2.2843 46.7194 37.7092
I/LnJ m 65.3 3.0219 71.2597 59.3403
KK/HlJ m 42.5556 2.849 48.1744 36.9367
LP/J m 36.79 2.7028 42.1205 31.4595
NOD/ShiLtJ m 43.3 2.7028 48.6305 37.9695
NZB/BlNJ m 43.5333 2.849 49.1522 37.9144
PL/J m 41.76 2.7028 47.0905 36.4295
SJL/J m 36.7778 2.849 42.3967 31.1589
SM/J m 47.4 2.4673 52.2661 42.5339
SWR/J m 44.3273 2.5771 49.4097 39.2448




  GWAS USING LINEAR MIXED MODELS