Project measure / variable:   Maurer1   QT_at

ID, description, units MPD:33246   QT_at   interval QT   [ms]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval QT atenolol 10mg

DBA/2JI/LnJC57BLKS/JC3H/HeOuJAKR/JSM/JBTBR T<+> Itpr3<tf>/JBALB/cByJSWR/J129S1/SvImJC58/JNZB/BlNJBALB/cJPL/JKK/HlJNOD/ShiLtJFVB/NJC57BL/6JA/JC3H/HeJLP/JCBA/JSJL/J ms 2030405060708090100110120130140femalemale


  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means57.2   ms
Median of the strain means56.9   ms
SD of the strain means± 5.08
Coefficient of variation (CV)0.0887
Min–max range of strain means48.9   –   69.1   ms
Mean sample size per strain9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 4646.3347 211.197 2.6319 0.0002
Residuals 196 15727.8256 80.244


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page: 1 - 10 / 23 (23)
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
129S1/SvImJ m 57.2 11.0   13 3.06 0.193 39.5, 81.8 0.0
A/J m 52.9 4.29   10 1.36 0.0811 47.5, 61.2 -0.85
AKR/J m 61.6 4.68   7 1.77 0.0759 55.5, 69.1 0.86
BALB/cByJ m 58.0 6.85   8 2.42 0.118 50.6, 70.8 0.16
BALB/cJ m 56.7 6.49   10 2.05 0.114 44.2, 65.6 -0.1
BTBR T+ Itpr3tf/J m 58.0 3.56   9 1.19 0.0614 54.2, 63.8 0.16
C3H/HeJ m 52.0 5.33   8 1.88 0.102 40.4, 56.2 -1.03
C3H/HeOuJ m 63.3 4.71   9 1.57 0.0745 58.4, 71.9 1.2
C57BL/6J m 53.3 2.14   9 0.714 0.0402 50.0, 55.5 -0.77
C57BLKS/J m 63.5 7.22   9 2.41 0.114 56.1, 77.9 1.24
C58/J m 57.0 4.23   12 1.22 0.0743 50.3, 63.0 -0.04
CBA/J m 50.4 10.4   6 4.24 0.206 39.5, 69.0 -1.34
DBA/2J m 69.1 16.6   6 6.79 0.241 44.8, 91.5 2.34
FVB/NJ m 54.3 4.09   14 1.09 0.0754 49.4, 62.5 -0.57
I/LnJ m 65.9 30.5   9 10.2 0.463 22.0, 137.0 1.71
KK/HlJ m 55.6 4.47   9 1.49 0.0803 48.7, 64.5 -0.32
LP/J m 50.9 3.11   10 0.983 0.061 47.0, 55.0 -1.24
NOD/ShiLtJ m 55.0 3.39   10 1.07 0.0616 49.9, 59.6 -0.44
NZB/BlNJ m 56.9 8.26   9 2.75 0.145 47.6, 75.1 -0.06
PL/J m 56.1 6.77   10 2.14 0.121 44.4, 67.7 -0.22
SJL/J m 48.9 7.99   9 2.66 0.163 29.9, 57.2 -1.64
SM/J m 61.5 3.74   12 1.08 0.0608 53.7, 68.7 0.84
SWR/J m 57.8 7.51   11 2.26 0.13 48.4, 72.3 0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 57.2385 2.4845 62.1382 52.3387
A/J m 52.89 2.8327 58.4766 47.3034
AKR/J m 61.6429 3.3858 68.3201 54.9656
BALB/cByJ m 57.9875 3.1671 64.2335 51.7415
BALB/cJ m 56.68 2.8327 62.2666 51.0934
BTBR T+ Itpr3tf/J m 58.0333 2.986 63.9221 52.1446
C3H/HeJ m 52.025 3.1671 58.271 45.779
C3H/HeOuJ m 63.2778 2.986 69.1665 57.389
C57BL/6J m 53.2889 2.986 59.1776 47.4001
C57BLKS/J m 63.5333 2.986 69.4221 57.6446
C58/J m 56.9667 2.5859 62.0665 51.8669
CBA/J m 50.3833 3.657 57.5955 43.1711
DBA/2J m 69.1 3.657 76.3122 61.8878
FVB/NJ m 54.2857 2.3941 59.0072 49.5642
I/LnJ m 65.9333 2.986 71.8221 60.0446
KK/HlJ m 55.6 2.986 61.4887 49.7113
LP/J m 50.93 2.8327 56.5166 45.3434
NOD/ShiLtJ m 55.04 2.8327 60.6266 49.4534
NZB/BlNJ m 56.8667 2.986 62.7554 50.9779
PL/J m 56.08 2.8327 61.6666 50.4934
SJL/J m 48.8556 2.986 54.7443 42.9668
SM/J m 61.5417 2.5859 66.6415 56.4419
SWR/J m 57.8 2.7009 63.1266 52.4734




  GWAS USING LINEAR MIXED MODELS

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