Project measure / variable:   Maurer1   QRS_iso1

ID, description, units MPD:33243   QRS_iso1   interval QRS   [ms]  isoprot 1mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval QRS isoprot 1mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means12.0   ms
Median of the strain means12.1   ms
SD of the strain means± 1.07
Coefficient of variation (CV)0.0887
Min–max range of strain means9.98   –   13.9   ms
Mean sample size per strain10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 247.93 11.2695 2.5606 0.0003
Residuals 206 906.6274 4.4011


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 13.4 2.0   13 0.555 0.149 9.85, 16.5 1.31
A/J m 12.2 2.79   10 0.882 0.228 8.5, 19.4 0.18
AKR/J m 10.9 1.13   10 0.357 0.104 9.0, 13.0 -1.04
BALB/cByJ m 12.4 1.69   9 0.565 0.137 9.81, 15.0 0.37
BALB/cJ m 13.1 1.59   10 0.504 0.121 10.1, 16.0 1.03
BTBR T+ Itpr3tf/J m 13.9 1.2   9 0.399 0.0859 12.1, 16.0 1.78
C3H/HeJ m 9.98 2.98   9 0.992 0.298 3.27, 12.8 -1.9
C3H/HeOuJ m 11.2 0.704   10 0.223 0.0632 10.0, 12.2 -0.76
C57BL/6J m 12.1 1.34   9 0.445 0.11 9.97, 14.9 0.09
C57BLKS/J m 11.6 1.97   10 0.624 0.17 8.88, 14.8 -0.38
C58/J m 12.8 2.06   12 0.595 0.161 11.2, 18.8 0.74
CBA/J m 10.3 3.6   10 1.14 0.349 8.12, 20.3 -1.6
DBA/2J m 10.9 1.97   7 0.746 0.181 8.0, 14.0 -1.04
FVB/NJ m 12.7 1.47   13 0.408 0.116 10.8, 15.4 0.65
I/LnJ m 10.7 2.19   9 0.731 0.204 8.18, 14.0 -1.23
KK/HlJ m 12.1 1.38   10 0.436 0.114 10.1, 14.5 0.09
LP/J m 13.3 1.21   10 0.383 0.0914 11.9, 15.6 1.21
NOD/ShiLtJ m 11.9 0.951   10 0.301 0.0799 10.6, 13.5 -0.1
NZB/BlNJ m 12.4 3.23   9 1.08 0.261 9.15, 18.8 0.37
PL/J m 12.9 1.46   9 0.485 0.113 10.0, 15.2 0.84
SJL/J m 13.0 2.35   9 0.784 0.18 9.85, 16.0 0.93
SM/J m 11.2 2.98   13 0.825 0.265 6.79, 16.3 -0.76
SWR/J m 11.2 2.62   9 0.872 0.234 7.9, 16.6 -0.76


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 13.4269 0.5818 14.5741 12.2798
A/J m 12.21 0.6634 13.5179 10.9021
AKR/J m 10.86 0.6634 12.1679 9.5521
BALB/cByJ m 12.3678 0.6993 13.7465 10.9891
BALB/cJ m 13.13 0.6634 14.4379 11.8221
BTBR T+ Itpr3tf/J m 13.9444 0.6993 15.3231 12.5658
C3H/HeJ m 9.9778 0.6993 11.3565 8.5991
C3H/HeOuJ m 11.15 0.6634 12.4579 9.8421
C57BL/6J m 12.13 0.6993 13.5087 10.7513
C57BLKS/J m 11.638 0.6634 12.9459 10.3301
C58/J m 12.8333 0.6056 14.0273 11.6394
CBA/J m 10.299 0.6634 11.6069 8.9911
DBA/2J m 10.9143 0.7929 12.4776 9.351
FVB/NJ m 12.7231 0.5818 13.8702 11.5759
I/LnJ m 10.7367 0.6993 12.1154 9.358
KK/HlJ m 12.13 0.6634 13.4379 10.8221
LP/J m 13.26 0.6634 14.5679 11.9521
NOD/ShiLtJ m 11.9 0.6634 13.2079 10.5921
NZB/BlNJ m 12.35 0.6993 13.7287 10.9713
PL/J m 12.9222 0.6993 14.3009 11.5435
SJL/J m 13.0389 0.6993 14.4176 11.6602
SM/J m 11.2285 0.5818 12.3756 10.0813
SWR/J m 11.1767 0.6993 12.5554 9.798




  GWAS USING LINEAR MIXED MODELS