Project measure / variable:   Maurer1   QRS_at

ID, description, units MPD:33242   QRS_at   interval QRS   [ms]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval QRS atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means13.3   ms
Median of the strain means13.5   ms
SD of the strain means± 1.23
Coefficient of variation (CV)0.0922
Min–max range of strain means10.2   –   14.8   ms
Mean sample size per strain9.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 281.1706 12.7805 3.2782 < 0.0001
Residuals 195 760.2409 3.8987


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 14.8 2.17   13 0.603 0.147 12.8, 19.0 1.21
A/J m 14.0 2.08   10 0.657 0.149 11.0, 18.9 0.56
AKR/J m 12.3 1.9   7 0.719 0.155 9.0, 14.5 -0.83
BALB/cByJ m 14.6 4.63   8 1.64 0.317 12.1, 25.5 1.05
BALB/cJ m 14.5 2.73   10 0.865 0.189 10.8, 20.4 0.97
BTBR T+ Itpr3tf/J m 14.8 0.959   9 0.32 0.065 13.5, 16.0 1.21
C3H/HeJ m 11.6 0.735   8 0.26 0.0631 10.5, 12.4 -1.4
C3H/HeOuJ m 12.8 1.79   9 0.598 0.14 9.53, 15.2 -0.42
C57BL/6J m 13.6 1.45   9 0.483 0.107 10.5, 15.0 0.23
C57BLKS/J m 13.0 1.25   9 0.415 0.0957 10.9, 14.7 -0.26
C58/J m 14.6 1.88   12 0.543 0.129 12.6, 18.7 1.05
CBA/J m 10.2 1.48   6 0.603 0.144 8.0, 12.3 -2.54
DBA/2J m 13.7 2.54   6 1.04 0.185 9.32, 17.0 0.32
FVB/NJ m 12.4 0.917   14 0.245 0.0742 10.6, 13.9 -0.74
I/LnJ m 11.4 1.63   8 0.575 0.143 9.0, 13.7 -1.56
KK/HlJ m 13.0 1.36   9 0.452 0.104 10.5, 14.9 -0.26
LP/J m 14.1 2.1   10 0.665 0.149 11.0, 17.5 0.64
NOD/ShiLtJ m 12.3 0.911   10 0.288 0.0741 10.9, 13.4 -0.83
NZB/BlNJ m 13.4 1.32   9 0.44 0.0988 11.2, 15.2 0.07
PL/J m 14.3 2.32   10 0.733 0.162 11.0, 17.8 0.8
SJL/J m 12.7 1.69   9 0.563 0.133 9.21, 15.7 -0.5
SM/J m 14.6 2.24   12 0.647 0.154 11.1, 19.3 1.05
SWR/J m 13.5 2.13   11 0.643 0.159 9.87, 17.7 0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 14.7846 0.5476 15.8647 13.7046
A/J m 13.98 0.6244 15.2114 12.7486
AKR/J m 12.2571 0.7463 13.729 10.7853
BALB/cByJ m 14.625 0.6981 16.0018 13.2482
BALB/cJ m 14.46 0.6244 15.6914 13.2286
BTBR T+ Itpr3tf/J m 14.7556 0.6582 16.0536 13.4575
C3H/HeJ m 11.6375 0.6981 13.0143 10.2607
C3H/HeOuJ m 12.8144 0.6582 14.1125 11.5164
C57BL/6J m 13.5778 0.6582 14.8758 12.2797
C57BLKS/J m 13.0222 0.6582 14.3203 11.7242
C58/J m 14.6167 0.57 15.7408 13.4925
CBA/J m 10.24 0.8061 11.8298 8.6502
DBA/2J m 13.7033 0.8061 15.2931 12.1136
FVB/NJ m 12.3643 0.5277 13.405 11.3235
I/LnJ m 11.375 0.6981 12.7518 9.9982
KK/HlJ m 13.0 0.6582 14.298 11.702
LP/J m 14.12 0.6244 15.3514 12.8886
NOD/ShiLtJ m 12.29 0.6244 13.5214 11.0586
NZB/BlNJ m 13.3556 0.6582 14.6536 12.0575
PL/J m 14.32 0.6244 15.5514 13.0886
SJL/J m 12.7344 0.6582 14.0325 11.4364
SM/J m 14.5917 0.57 15.7158 13.4675
SWR/J m 13.4518 0.5953 14.6259 12.2777




  GWAS USING LINEAR MIXED MODELS