Project measure / variable:   Maurer1   RR_iso10

ID, description, units MPD:33240   RR_iso10   interval RR   [ms]  isoprot 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval RR isoprot 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means115   ms
Median of the strain means113   ms
SD of the strain means± 12.0
Coefficient of variation (CV)0.104
Min–max range of strain means97.2   –   151   ms
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 28256.5239 1284.3875 8.4741 < 0.0001
Residuals 202 30616.2319 151.5655


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 106.0 6.27   12 1.81 0.0593 96.8, 120.0 -0.74
A/J m 120.0 10.7   10 3.38 0.0893 109.0, 137.0 0.43
AKR/J m 118.0 21.0   9 6.99 0.178 97.4, 163.0 0.26
BALB/cByJ m 125.0 12.6   9 4.19 0.101 104.0, 152.0 0.85
BALB/cJ m 118.0 17.6   8 6.22 0.149 98.0, 146.0 0.26
BTBR T+ Itpr3tf/J m 119.0 15.6   9 5.21 0.132 93.0, 146.0 0.35
C3H/HeJ m 112.0 6.35   9 2.12 0.0569 99.2, 120.0 -0.24
C3H/HeOuJ m 113.0 14.3   11 4.3 0.126 98.3, 138.0 -0.15
C57BL/6J m 97.2 4.12   8 1.46 0.0424 92.0, 105.0 -1.47
C57BLKS/J m 112.0 10.1   10 3.19 0.0899 100.0, 125.0 -0.24
C58/J m 107.0 5.9   12 1.7 0.055 100.0, 118.0 -0.65
CBA/J m 103.0 8.73   10 2.76 0.0843 90.4, 117.0 -0.99
DBA/2J m 151.0 15.9   8 5.61 0.105 133.0, 176.0 3.02
FVB/NJ m 117.0 7.47   13 2.07 0.0639 106.0, 138.0 0.18
I/LnJ m 117.0 15.6   10 4.93 0.133 92.5, 137.0 0.18
KK/HlJ m 107.0 15.3   10 4.83 0.143 91.0, 139.0 -0.65
LP/J m 111.0 10.2   8 3.61 0.092 99.7, 132.0 -0.32
NOD/ShiLtJ m 117.0 12.6   10 3.97 0.108 96.1, 136.0 0.18
NZB/BlNJ m 112.0 14.9   7 5.62 0.133 99.1, 143.0 -0.24
PL/J m 140.0 21.9   10 6.93 0.157 98.5, 175.0 2.1
SJL/J m 115.0 7.0   10 2.21 0.0606 105.0, 127.0 0.01
SM/J m 101.0 3.6   13 1.0 0.0356 93.7, 107.0 -1.16
SWR/J m 103.0 9.15   9 3.05 0.0888 93.0, 120.0 -0.99


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 105.65 3.5539 112.6576 98.6424
A/J m 119.8 3.8931 127.4764 112.1236
AKR/J m 118.0444 4.1037 126.1361 109.9528
BALB/cByJ m 124.5556 4.1037 132.6472 116.4639
BALB/cJ m 118.375 4.3527 126.9575 109.7925
BTBR T+ Itpr3tf/J m 118.6 4.1037 126.6916 110.5084
C3H/HeJ m 111.6889 4.1037 119.7805 103.5972
C3H/HeOuJ m 112.9364 3.712 120.2555 105.6172
C57BL/6J m 97.25 4.3527 105.8325 88.6675
C57BLKS/J m 112.1 3.8931 119.7764 104.4236
C58/J m 107.3333 3.5539 114.3409 100.3258
CBA/J m 103.45 3.8931 111.1264 95.7736
DBA/2J m 150.875 4.3527 159.4575 142.2925
FVB/NJ m 116.8462 3.4145 123.5788 110.1135
I/LnJ m 117.35 3.8931 125.0264 109.6736
KK/HlJ m 107.04 3.8931 114.7164 99.3636
LP/J m 111.0875 4.3527 119.67 102.505
NOD/ShiLtJ m 116.81 3.8931 124.4864 109.1336
NZB/BlNJ m 111.8714 4.6532 121.0465 102.6964
PL/J m 139.75 3.8931 147.4264 132.0736
SJL/J m 115.4 3.8931 123.0764 107.7236
SM/J m 101.1769 3.4145 107.9096 94.4443
SWR/J m 103.0 4.1037 111.0916 94.9084




  GWAS USING LINEAR MIXED MODELS