Project measure / variable:   Maurer1   RR_at

ID, description, units MPD:33238   RR_at   interval RR   [ms]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval RR atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means154   ms
Median of the strain means153   ms
SD of the strain means± 20.6
Coefficient of variation (CV)0.134
Min–max range of strain means119   –   203   ms
Mean sample size per strain9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 77314.5151 3514.2961 10.1688 < 0.0001
Residuals 196 67736.9118 345.5965


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 149.0 17.5   13 4.87 0.117 127.0, 179.0 -0.26
A/J m 157.0 12.9   10 4.08 0.0821 138.0, 180.0 0.12
AKR/J m 126.0 20.8   7 7.87 0.166 98.5, 161.0 -1.38
BALB/cByJ m 163.0 20.7   8 7.31 0.127 139.0, 202.0 0.42
BALB/cJ m 157.0 24.2   10 7.66 0.155 117.0, 199.0 0.12
BTBR T+ Itpr3tf/J m 153.0 10.7   9 3.56 0.0697 142.0, 170.0 -0.07
C3H/HeJ m 172.0 25.0   8 8.83 0.146 125.0, 206.0 0.85
C3H/HeOuJ m 154.0 7.8   9 2.6 0.0508 145.0, 167.0 -0.02
C57BL/6J m 153.0 11.9   9 3.97 0.0779 134.0, 170.0 -0.07
C57BLKS/J m 203.0 18.2   9 6.06 0.0896 172.0, 232.0 2.35
C58/J m 147.0 12.7   12 3.65 0.0862 130.0, 169.0 -0.36
CBA/J m 152.0 12.5   6 5.1 0.082 138.0, 174.0 -0.12
DBA/2J m 200.0 42.5   6 17.3 0.212 151.0, 268.0 2.21
FVB/NJ m 156.0 23.0   14 6.14 0.147 127.0, 195.0 0.08
I/LnJ m 183.0 25.6   9 8.54 0.14 148.0, 227.0 1.38
KK/HlJ m 119.0 8.89   9 2.96 0.0748 104.0, 137.0 -1.72
LP/J m 142.0 14.7   10 4.65 0.104 122.0, 175.0 -0.6
NOD/ShiLtJ m 162.0 23.5   10 7.44 0.145 126.0, 212.0 0.37
NZB/BlNJ m 125.0 12.7   9 4.23 0.102 109.0, 148.0 -1.43
PL/J m 153.0 20.5   10 6.47 0.133 122.0, 186.0 -0.07
SJL/J m 140.0 19.4   9 6.45 0.139 112.0, 165.0 -0.7
SM/J m 142.0 10.1   12 2.9 0.0707 131.0, 163.0 -0.6
SWR/J m 144.0 13.2   11 3.98 0.0917 126.0, 161.0 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 149.3846 5.156 159.553 139.2163
A/J m 156.9 5.8787 168.4937 145.3063
AKR/J m 125.5 7.0264 139.3571 111.6429
BALB/cByJ m 162.875 6.5726 175.8372 149.9128
BALB/cJ m 156.7 5.8787 168.2937 145.1063
BTBR T+ Itpr3tf/J m 153.4444 6.1967 165.6653 141.2236
C3H/HeJ m 171.625 6.5726 184.5872 158.6628
C3H/HeOuJ m 153.5556 6.1967 165.7764 141.3347
C57BL/6J m 152.7778 6.1967 164.9986 140.5569
C57BLKS/J m 202.8889 6.1967 215.1097 190.668
C58/J m 146.9167 5.3665 157.5002 136.3331
CBA/J m 152.3333 7.5894 167.3008 137.3659
DBA/2J m 199.8333 7.5894 214.8008 184.8659
FVB/NJ m 155.7143 4.9684 165.5128 145.9158
I/LnJ m 183.4444 6.1967 195.6653 171.2236
KK/HlJ m 118.7778 6.1967 130.9986 106.5569
LP/J m 141.6 5.8787 153.1937 130.0063
NOD/ShiLtJ m 162.4 5.8787 173.9937 150.8063
NZB/BlNJ m 125.1111 6.1967 137.332 112.8903
PL/J m 153.4 5.8787 164.9937 141.8063
SJL/J m 139.5556 6.1967 151.7764 127.3347
SM/J m 142.3333 5.3665 152.9169 131.7498
SWR/J m 144.0 5.6052 155.0542 132.9458




  GWAS USING LINEAR MIXED MODELS