Project measure / variable:   Maurer1   P_dur_iso10

ID, description, units MPD:33232   P_dur_iso10   duration P-wave   [ms]  isoprot 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - duration P-wave isoprot 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means10.9   ms
Median of the strain means10.5   ms
SD of the strain means± 1.05
Coefficient of variation (CV)0.0965
Min–max range of strain means9.41   –   13.4   ms
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 217.7091 9.8959 4.6297 < 0.0001
Residuals 202 431.7726 2.1375


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 11.8 1.43   12 0.413 0.122 8.02, 13.4 0.91
A/J m 10.2 0.959   10 0.303 0.0937 9.06, 12.0 -0.62
AKR/J m 12.2 2.72   9 0.906 0.223 5.97, 15.0 1.29
BALB/cByJ m 11.7 1.87   9 0.624 0.16 8.97, 15.0 0.81
BALB/cJ m 11.9 2.18   8 0.77 0.184 9.0, 15.0 1.0
BTBR T+ Itpr3tf/J m 13.4 2.24   9 0.747 0.167 11.0, 18.1 2.43
C3H/HeJ m 10.0 0.677   9 0.226 0.0677 9.0, 10.9 -0.81
C3H/HeOuJ m 10.1 1.28   11 0.387 0.127 8.07, 13.0 -0.72
C57BL/6J m 9.93 1.51   8 0.534 0.152 8.14, 12.0 -0.88
C57BLKS/J m 9.53 2.25   10 0.711 0.236 6.12, 13.0 -1.26
C58/J m 10.5 1.17   12 0.337 0.111 8.07, 12.0 -0.34
CBA/J m 10.4 0.448   10 0.142 0.0432 10.0, 11.0 -0.43
DBA/2J m 13.1 2.06   8 0.727 0.157 11.0, 16.4 2.15
FVB/NJ m 10.7 0.721   13 0.2 0.0674 9.28, 12.3 -0.14
I/LnJ m 10.4 1.47   10 0.466 0.142 8.08, 12.7 -0.43
KK/HlJ m 10.8 1.34   10 0.422 0.123 8.52, 13.0 -0.05
LP/J m 10.2 1.64   8 0.579 0.16 8.0, 12.0 -0.62
NOD/ShiLtJ m 10.5 0.829   10 0.262 0.0788 8.94, 11.8 -0.34
NZB/BlNJ m 10.8 1.12   7 0.425 0.104 8.48, 11.8 -0.05
PL/J m 10.4 1.39   10 0.438 0.133 8.17, 12.7 -0.43
SJL/J m 11.2 0.604   10 0.191 0.0539 10.0, 11.8 0.33
SM/J m 10.4 0.911   13 0.253 0.0877 9.0, 12.0 -0.43
SWR/J m 9.41 0.963   9 0.321 0.102 8.0, 11.1 -1.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 11.7683 0.422 12.6005 10.9361
A/J m 10.237 0.4623 11.1486 9.3254
AKR/J m 12.1967 0.4873 13.1576 11.2357
BALB/cByJ m 11.73 0.4873 12.6909 10.7691
BALB/cJ m 11.8625 0.5169 12.8817 10.8433
BTBR T+ Itpr3tf/J m 13.4333 0.4873 14.3943 12.4724
C3H/HeJ m 10.0056 0.4873 10.9665 9.0446
C3H/HeOuJ m 10.1073 0.4408 10.9765 9.2381
C57BL/6J m 9.9275 0.5169 10.9467 8.9083
C57BLKS/J m 9.532 0.4623 10.4436 8.6204
C58/J m 10.465 0.422 11.2972 9.6328
CBA/J m 10.39 0.4623 11.3016 9.4784
DBA/2J m 13.1125 0.5169 14.1317 12.0933
FVB/NJ m 10.7062 0.4055 11.5057 9.9066
I/LnJ m 10.367 0.4623 11.2786 9.4554
KK/HlJ m 10.833 0.4623 11.7446 9.9214
LP/J m 10.2375 0.5169 11.2567 9.2183
NOD/ShiLtJ m 10.52 0.4623 11.4316 9.6084
NZB/BlNJ m 10.84 0.5526 11.9296 9.7504
PL/J m 10.446 0.4623 11.3576 9.5344
SJL/J m 11.2 0.4623 12.1116 10.2884
SM/J m 10.3846 0.4055 11.1842 9.5851
SWR/J m 9.4144 0.4873 10.3754 8.4535




  GWAS USING LINEAR MIXED MODELS