Project measure / variable:   Maurer1   S_amp_iso10

ID, description, units MPD:33228   S_amp_iso10   amplitude of S-wave   [mV]  isoprot 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   22 strains     sex: m     age: 7-13wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Maurer1 - amplitude of S-wave isoprot 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested22 strains
Mean of the strain means-0.226   mV
Median of the strain means-0.217   mV
SD of the strain means± 0.124
Coefficient of variation (CV)-0.547
Min–max range of strain means-0.595   –   -0.0610   mV
Mean sample size per strain8.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 3.2982 0.1571 7.4648 < 0.0001
Residuals 171 3.5978 0.021


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m -0.402 0.238   12 0.0686 -0.591 -0.85, -0.08 -1.42
A/J m -0.155 0.0354   2   0.025 -0.228 -0.18, -0.13 0.57
AKR/J m -0.312 0.232   9 0.0774 -0.744 -0.74, -0.1 -0.69
BALB/cByJ m -0.12 0.141   4 0.0704 -1.17 -0.31, 0.02 0.86
BALB/cJ m -0.243 0.0719   8 0.0254 -0.296 -0.32, -0.12 -0.14
BTBR T+ Itpr3tf/J m -0.247 0.0768   9 0.0256 -0.311 -0.37, -0.15 -0.17
C3H/HeJ m -0.37 0.152   9 0.0507 -0.411 -0.61, -0.13 -1.16
C3H/HeOuJ m -0.096 0.364   5 0.163 -3.79 -0.48, 0.5 1.05
C57BL/6J m -0.314 0.145   8 0.0513 -0.462 -0.54, -0.08 -0.71
C57BLKS/J m -0.197 0.0971   10 0.0307 -0.493 -0.34, -0.02 0.24
C58/J m -0.169 0.0687   12 0.0198 -0.406 -0.3, -0.07 0.46
DBA/2J m -0.108 0.166   5 0.0741 -1.54 -0.325, 0.068 0.95
FVB/NJ m -0.266 0.102   13 0.0282 -0.381 -0.43, -0.09 -0.32
I/LnJ m -0.122 0.0711   10 0.0225 -0.583 -0.27, -0.05 0.84
KK/HlJ m -0.263 0.0884   10 0.028 -0.336 -0.36, -0.13 -0.3
LP/J m -0.238 0.152   8 0.0538 -0.641 -0.43, 0.0 -0.1
NOD/ShiLtJ m -0.276 0.112   10 0.0353 -0.405 -0.46, -0.12 -0.4
NZB/BlNJ m -0.15 0.0766   7 0.0289 -0.511 -0.31, -0.08 0.61
PL/J m -0.061 0.0799   10 0.0253 -1.31 -0.2, 0.05 1.33
SJL/J m -0.116 0.0465   10 0.0147 -0.401 -0.2, -0.06 0.89
SM/J m -0.595 0.231   13 0.0641 -0.388 -1.07, -0.34 -2.98
SWR/J m -0.154 0.0559   9 0.0186 -0.362 -0.23, -0.07 0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m -0.4017 0.0419 -0.319 -0.4843
A/J m -0.155 0.1026 0.0475 -0.3575
AKR/J m -0.3122 0.0484 -0.2168 -0.4077
BALB/cByJ m -0.12 0.0725 0.0232 -0.2632
BALB/cJ m -0.2425 0.0513 -0.1413 -0.3437
BTBR T+ Itpr3tf/J m -0.2467 0.0484 -0.1512 -0.3421
C3H/HeJ m -0.37 0.0484 -0.2746 -0.4654
C3H/HeOuJ m -0.096 0.0649 0.032 -0.224
C57BL/6J m -0.3137 0.0513 -0.2125 -0.415
C57BLKS/J m -0.197 0.0459 -0.1065 -0.2875
C58/J m -0.1692 0.0419 -0.0865 -0.2518
DBA/2J m -0.1076 0.0649 0.0204 -0.2356
FVB/NJ m -0.2662 0.0402 -0.1867 -0.3456
I/LnJ m -0.122 0.0459 -0.0315 -0.2125
KK/HlJ m -0.263 0.0459 -0.1725 -0.3535
LP/J m -0.2375 0.0513 -0.1363 -0.3387
NOD/ShiLtJ m -0.276 0.0459 -0.1855 -0.3665
NZB/BlNJ m -0.15 0.0548 -0.0418 -0.2582
PL/J m -0.061 0.0459 0.0295 -0.1515
SJL/J m -0.116 0.0459 -0.0255 -0.2065
SM/J m -0.5954 0.0402 -0.516 -0.6748
SWR/J m -0.1544 0.0484 -0.059 -0.2499




  GWAS USING LINEAR MIXED MODELS