Project measure / variable:   Maurer1   S_amp_iso1

ID, description, units MPD:33227   S_amp_iso1   amplitude of S-wave   [mV]  isoprot 1mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   22 strains     sex: m     age: 7-13wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Maurer1 - amplitude of S-wave isoprot 1mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested22 strains
Mean of the strain means-0.247   mV
Median of the strain means-0.229   mV
SD of the strain means± 0.114
Coefficient of variation (CV)-0.462
Min–max range of strain means-0.548   –   -0.104   mV
Mean sample size per strain9.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 2.9705 0.1415 6.8498 < 0.0001
Residuals 178 3.6758 0.0207


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m -0.482 0.224   13 0.0622 -0.465 -0.79, -0.03 -2.06
A/J m -0.195 0.148   2   0.105 -0.761 -0.3, -0.09 0.46
AKR/J m -0.24 0.204   10 0.0645 -0.85 -0.73, 0.02 0.06
BALB/cByJ m -0.104 0.0882   5 0.0394 -0.848 -0.24, -0.01 1.25
BALB/cJ m -0.256 0.102   10 0.0322 -0.397 -0.39, -0.06 -0.08
BTBR T+ Itpr3tf/J m -0.316 0.0988   9 0.0329 -0.313 -0.45, -0.11 -0.6
C3H/HeJ m -0.376 0.158   9 0.0527 -0.421 -0.59, -0.18 -1.13
C3H/HeOuJ m -0.188 0.111   5 0.0495 -0.589 -0.35, -0.07 0.52
C57BL/6J m -0.259 0.115   9 0.0382 -0.442 -0.52, -0.15 -0.1
C57BLKS/J m -0.204 0.0763   10 0.0241 -0.374 -0.33, -0.1 0.38
C58/J m -0.163 0.0767   12 0.0221 -0.469 -0.31, -0.03 0.74
DBA/2J m -0.177 0.243   4 0.122 -1.38 -0.43, 0.087 0.62
FVB/NJ m -0.343 0.1   13 0.0278 -0.292 -0.6, -0.21 -0.84
I/LnJ m -0.111 0.0398   9 0.0133 -0.358 -0.17, -0.04 1.19
KK/HlJ m -0.219 0.0886   10 0.028 -0.405 -0.4, -0.09 0.25
LP/J m -0.295 0.156   10 0.0493 -0.528 -0.51, -0.07 -0.42
NOD/ShiLtJ m -0.247 0.099   10 0.0313 -0.401 -0.37, -0.05 0.0
NZB/BlNJ m -0.17 0.0791   9 0.0264 -0.465 -0.27, -0.08 0.68
PL/J m -0.139 0.13   9 0.0434 -0.938 -0.39, 0.03 0.95
SJL/J m -0.121 0.0607   9 0.0202 -0.501 -0.2, -0.04 1.11
SM/J m -0.548 0.257   14 0.0687 -0.469 -1.04, -0.2 -2.63
SWR/J m -0.286 0.174   9 0.0579 -0.609 -0.7, -0.1 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m -0.4815 0.0399 -0.4029 -0.5602
A/J m -0.195 0.1016 0.0055 -0.3955
AKR/J m -0.24 0.0454 -0.1503 -0.3297
BALB/cByJ m -0.104 0.0643 0.0228 -0.2308
BALB/cJ m -0.256 0.0454 -0.1663 -0.3457
BTBR T+ Itpr3tf/J m -0.3156 0.0479 -0.221 -0.4101
C3H/HeJ m -0.3756 0.0479 -0.281 -0.4701
C3H/HeOuJ m -0.188 0.0643 -0.0612 -0.3148
C57BL/6J m -0.2589 0.0479 -0.1644 -0.3534
C57BLKS/J m -0.204 0.0454 -0.1143 -0.2937
C58/J m -0.1633 0.0415 -0.0815 -0.2452
DBA/2J m -0.1767 0.0719 -0.035 -0.3185
FVB/NJ m -0.3431 0.0399 -0.2644 -0.4217
I/LnJ m -0.1111 0.0479 -0.0166 -0.2056
KK/HlJ m -0.219 0.0454 -0.1293 -0.3087
LP/J m -0.295 0.0454 -0.2053 -0.3847
NOD/ShiLtJ m -0.247 0.0454 -0.1573 -0.3367
NZB/BlNJ m -0.17 0.0479 -0.0755 -0.2645
PL/J m -0.1389 0.0479 -0.0444 -0.2334
SJL/J m -0.1211 0.0479 -0.0266 -0.2156
SM/J m -0.5479 0.0384 -0.4721 -0.6236
SWR/J m -0.2856 0.0479 -0.191 -0.3801




  GWAS USING LINEAR MIXED MODELS