Project measure / variable:   Maurer1   R_amp_iso1

ID, description, units MPD:33223   R_amp_iso1   amplitude of R-wave   [mV]  isoprot 1mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - amplitude of R-wave isoprot 1mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means0.581   mV
Median of the strain means0.546   mV
SD of the strain means± 0.213
Coefficient of variation (CV)0.367
Min–max range of strain means0.247   –   1.10   mV
Mean sample size per strain9.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 8.5641 0.3893 8.0238 < 0.0001
Residuals 184 8.9268 0.0485


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.706 0.256   13 0.0711 0.363 0.34, 1.22 0.59
A/J m 0.73 0.156   2   0.11 0.213 0.62, 0.84 0.7
AKR/J m 0.391 0.163   10 0.0515 0.417 0.19, 0.62 -0.89
BALB/cByJ m 0.536 0.204   5 0.0914 0.381 0.42, 0.9 -0.21
BALB/cJ m 0.516 0.11   10 0.0346 0.212 0.31, 0.71 -0.3
BTBR T+ Itpr3tf/J m 1.1 0.308   9 0.103 0.281 0.63, 1.74 2.43
C3H/HeJ m 0.247 0.0879   9 0.0293 0.356 0.16, 0.38 -1.56
C3H/HeOuJ m 0.288 0.146   5 0.0652 0.506 0.13, 0.45 -1.37
C57BL/6J m 0.619 0.205   9 0.0684 0.332 0.42, 1.11 0.18
C57BLKS/J m 0.46 0.215   10 0.0679 0.467 0.1, 0.72 -0.57
C58/J m 0.944 0.251   12 0.0725 0.266 0.63, 1.39 1.7
CBA/J m 0.266 0.0675   4 0.0338 0.254 0.168, 0.32 -1.48
DBA/2J m 0.44 0.245   7 0.0926 0.557 0.174, 0.929 -0.66
FVB/NJ m 0.713 0.205   13 0.0569 0.288 0.24, 1.0 0.62
I/LnJ m 0.644 0.197   9 0.0657 0.306 0.39, 1.03 0.3
KK/HlJ m 0.602 0.137   10 0.0432 0.227 0.43, 0.9 0.1
LP/J m 0.624 0.297   10 0.0939 0.476 0.19, 1.19 0.2
NOD/ShiLtJ m 0.704 0.114   10 0.0361 0.162 0.53, 0.85 0.58
NZB/BlNJ m 0.546 0.255   9 0.0848 0.467 0.19, 0.96 -0.16
PL/J m 0.896 0.473   9 0.158 0.528 0.36, 1.85 1.48
SJL/J m 0.402 0.109   9 0.0364 0.272 0.24, 0.54 -0.84
SM/J m 0.471 0.168   14 0.045 0.357 0.25, 0.78 -0.51
SWR/J m 0.514 0.161   9 0.0536 0.313 0.26, 0.71 -0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.7062 0.0611 0.8267 0.5856
A/J m 0.73 0.1557 1.0373 0.4227
AKR/J m 0.391 0.0697 0.5284 0.2536
BALB/cByJ m 0.536 0.0985 0.7303 0.3417
BALB/cJ m 0.516 0.0697 0.6534 0.3786
BTBR T+ Itpr3tf/J m 1.0989 0.0734 1.2437 0.954
C3H/HeJ m 0.2467 0.0734 0.3915 0.1018
C3H/HeOuJ m 0.288 0.0985 0.4823 0.0937
C57BL/6J m 0.6189 0.0734 0.7637 0.474
C57BLKS/J m 0.46 0.0697 0.5974 0.3226
C58/J m 0.9442 0.0636 1.0696 0.8187
CBA/J m 0.2663 0.1101 0.4835 0.049
DBA/2J m 0.4396 0.0833 0.6038 0.2753
FVB/NJ m 0.7131 0.0611 0.8336 0.5926
I/LnJ m 0.6444 0.0734 0.7893 0.4996
KK/HlJ m 0.602 0.0697 0.7394 0.4646
LP/J m 0.624 0.0697 0.7614 0.4866
NOD/ShiLtJ m 0.704 0.0697 0.8414 0.5666
NZB/BlNJ m 0.5456 0.0734 0.6904 0.4007
PL/J m 0.8956 0.0734 1.0404 0.7507
SJL/J m 0.4022 0.0734 0.5471 0.2574
SM/J m 0.4714 0.0589 0.5876 0.3553
SWR/J m 0.5144 0.0734 0.6593 0.3696




  GWAS USING LINEAR MIXED MODELS