Project measure / variable:   Maurer1   P_amp_at

ID, description, units MPD:33214   P_amp_at   amplitude of P-wave   [mV]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - amplitude of P-wave atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means0.0960   mV
Median of the strain means0.0938   mV
SD of the strain means± 0.0264
Coefficient of variation (CV)0.275
Min–max range of strain means0.0508   –   0.139   mV
Mean sample size per strain9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 0.14 0.0064 12.5308 < 0.0001
Residuals 196 0.0995 0.0005


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.122 0.0331   13 0.00919 0.273 0.08, 0.18 0.98
A/J m 0.096 0.028   10 0.00884 0.291 0.06, 0.14 0.0
AKR/J m 0.0886 0.0324   7 0.0122 0.365 0.05, 0.12 -0.28
BALB/cByJ m 0.0938 0.0185   8 0.00653 0.197 0.07, 0.12 -0.08
BALB/cJ m 0.078 0.0175   10 0.00554 0.225 0.06, 0.12 -0.68
BTBR T+ Itpr3tf/J m 0.127 0.0312   9 0.0104 0.247 0.1, 0.18 1.17
C3H/HeJ m 0.113 0.0198   8 0.00701 0.176 0.09, 0.15 0.64
C3H/HeOuJ m 0.111 0.0247   9 0.00824 0.222 0.08, 0.16 0.57
C57BL/6J m 0.0656 0.0159   9 0.0053 0.243 0.04, 0.09 -1.15
C57BLKS/J m 0.0711 0.0127   9 0.00423 0.178 0.05, 0.09 -0.94
C58/J m 0.0508 0.0173   12 0.00499 0.34 0.03, 0.08 -1.71
CBA/J m 0.0538 0.0096   6 0.00392 0.178 0.043, 0.07 -1.6
DBA/2J m 0.139 0.0173   6 0.00704 0.124 0.12, 0.16 1.63
FVB/NJ m 0.09 0.0162   14 0.00432 0.18 0.06, 0.12 -0.23
I/LnJ m 0.137 0.024   9 0.00799 0.175 0.1, 0.17 1.55
KK/HlJ m 0.0611 0.0252   9 0.00841 0.413 0.02, 0.09 -1.32
LP/J m 0.127 0.0337   10 0.0107 0.265 0.09, 0.19 1.17
NOD/ShiLtJ m 0.107 0.0195   10 0.00616 0.182 0.09, 0.15 0.42
NZB/BlNJ m 0.08 0.01   9 0.00333 0.125 0.06, 0.09 -0.61
PL/J m 0.093 0.0125   10 0.00396 0.135 0.07, 0.11 -0.11
SJL/J m 0.0956 0.0181   9 0.00603 0.189 0.07, 0.12 -0.02
SM/J m 0.128 0.0233   12 0.00672 0.181 0.09, 0.17 1.21
SWR/J m 0.08 0.0253   11 0.00763 0.316 0.04, 0.11 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.1215 0.0063 0.1339 0.1092
A/J m 0.096 0.0071 0.1101 0.0819
AKR/J m 0.0886 0.0085 0.1054 0.0718
BALB/cByJ m 0.0938 0.008 0.1095 0.078
BALB/cJ m 0.078 0.0071 0.0921 0.0639
BTBR T+ Itpr3tf/J m 0.1267 0.0075 0.1415 0.1119
C3H/HeJ m 0.1125 0.008 0.1282 0.0968
C3H/HeOuJ m 0.1111 0.0075 0.1259 0.0963
C57BL/6J m 0.0656 0.0075 0.0804 0.0507
C57BLKS/J m 0.0711 0.0075 0.0859 0.0563
C58/J m 0.0508 0.0065 0.0637 0.038
CBA/J m 0.0538 0.0092 0.072 0.0357
DBA/2J m 0.1392 0.0092 0.1573 0.121
FVB/NJ m 0.09 0.006 0.1019 0.0781
I/LnJ m 0.1367 0.0075 0.1515 0.1219
KK/HlJ m 0.0611 0.0075 0.0759 0.0463
LP/J m 0.127 0.0071 0.1411 0.1129
NOD/ShiLtJ m 0.107 0.0071 0.1211 0.0929
NZB/BlNJ m 0.08 0.0075 0.0948 0.0652
PL/J m 0.093 0.0071 0.1071 0.0789
SJL/J m 0.0956 0.0075 0.1104 0.0807
SM/J m 0.1283 0.0065 0.1412 0.1155
SWR/J m 0.08 0.0068 0.0934 0.0666




  GWAS USING LINEAR MIXED MODELS