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Project measure / variable:   Schonfeld1   hTG

ID, description, units MPD:32348   hTG   hepatic triglycerides (5h fast)   [mg/g]  
Data set, strains Schonfeld1   inbred   11 strains     sex: both     age: 9-13wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Schonfeld1 - hepatic triglycerides (5h fast)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means104   mg/g 111   mg/g
Median of the strain means80.9   mg/g 79.0   mg/g
SD of the strain means± 71.0 ± 99.3
Coefficient of variation (CV)0.684 0.897
Min–max range of strain means44.5   –   283   mg/g 55.0   –   384   mg/g
Mean sample size per strain6.2   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1878.069 1878.069 0.9886 0.3229
strain 8 757560.1692 94695.0211 49.8447 < 0.0001
sex:strain 8 42023.8815 5252.9852 2.765 0.009
Residuals 87 165282.657 1899.8007


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 98.8 37.7   10 11.9 0.381 41.4, 152.0 -0.07
129X1/SvJ m 69.9 19.5   5 8.7 0.278 50.4, 93.8 -0.41
AKR/J f 77.6 18.3   5 8.2 0.236 61.8, 98.9 -0.37
BALB/cByJ f 283.0 88.9   10 28.1 0.314 182.0, 504.0 2.52
BALB/cByJ m 384.0 93.7   5 41.9 0.244 270.0, 473.0 2.75
BALB/cJ m 63.8 10.9   5 4.86 0.17 49.6, 78.0 -0.47
C3H/HeJ f 51.5 12.3   5 5.5 0.239 35.1, 69.3 -0.74
C3H/HeJ m 59.7 8.06   5 3.6 0.135 51.4, 69.6 -0.51
C57BL/6ByJ f 124.0 10.8   5 4.82 0.0873 108.0, 135.0 0.28
C57BL/6ByJ m 106.0 36.0   5 16.1 0.341 67.0, 157.0 -0.05
C57BL/6J f 150.0 52.7   10 16.7 0.352 63.1, 236.0 0.65
C57BL/6J m 134.0 17.5   5 7.82 0.131 105.0, 151.0 0.23
DBA/1LacJ f 84.2 34.3   5 15.3 0.407 59.8, 142.0 -0.28
DBA/1LacJ m 55.3 7.41   5 3.31 0.134 43.0, 60.2 -0.56
NZB/BlNJ f 63.0 11.1   5 4.96 0.176 49.9, 76.1 -0.58
NZB/BlNJ m 91.1 29.8   5 13.3 0.327 40.6, 116.0 -0.2
PL/J f 62.0 8.56   5 3.83 0.138 50.1, 71.9 -0.59
PL/J m 88.1 9.23   5 4.13 0.105 76.4, 98.7 -0.23
SWR/J f 44.5 9.61   5 4.3 0.216 34.0, 57.3 -0.84
SWR/J m 55.0 22.7   5 10.1 0.412 35.5, 91.7 -0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 98.83 13.7833 126.2259 71.4341
129X1/SvJ m 69.94 19.4926 108.6836 31.1964
BALB/cByJ f 282.8 13.7833 310.1959 255.4041
BALB/cByJ m 383.6 19.4926 422.3436 344.8564
C3H/HeJ f 51.46 19.4926 90.2036 12.7164
C3H/HeJ m 59.7 19.4926 98.4436 20.9564
C57BL/6ByJ f 123.6 19.4926 162.3436 84.8564
C57BL/6ByJ m 105.5 19.4926 144.2436 66.7564
C57BL/6J f 149.98 13.7833 177.3759 122.5841
C57BL/6J m 133.8 19.4926 172.5436 95.0564
DBA/1LacJ f 84.16 19.4926 122.9036 45.4164
DBA/1LacJ m 55.32 19.4926 94.0636 16.5764
NZB/BlNJ f 63.02 19.4926 101.7636 24.2764
NZB/BlNJ m 91.08 19.4926 129.8236 52.3364
PL/J f 62.02 19.4926 100.7636 23.2764
PL/J m 88.1 19.4926 126.8436 49.3564
SWR/J f 44.46 19.4926 83.2036 5.7164
SWR/J m 55.0 19.4926 93.7436 16.2564


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 84.385 11.9367 108.1105 60.6595
BALB/cByJ both 333.2 11.9367 356.9255 309.4745
C3H/HeJ both 55.58 13.7833 82.9759 28.1841
C57BL/6ByJ both 114.55 13.7833 141.9459 87.1541
C57BL/6J both 141.89 11.9367 165.6155 118.1645
DBA/1LacJ both 69.74 13.7833 97.1359 42.3441
NZB/BlNJ both 77.05 13.7833 104.4459 49.6541
PL/J both 75.06 13.7833 102.4559 47.6641
SWR/J both 49.73 13.7833 77.1259 22.3341




  GWAS USING LINEAR MIXED MODELS