Project measure / variable:   Schonfeld1   BHB


  STRAIN COMPARISON PLOT
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Schonfeld1 - beta-hydroxybutyrate (plasma BHB)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means0.864   mM 0.874   mM
Median of the strain means0.837   mM 0.874   mM
SD of the strain means± 0.165 ± 0.143
Coefficient of variation (CV)0.191 0.164
Min–max range of strain means0.630   –   1.20   mM 0.690   –   1.12   mM
Mean sample size per strain6.2   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0166 0.0166 0.3458 0.5581
strain 8 1.5563 0.1945 4.0452 0.0004
sex:strain 8 0.4989 0.0624 1.2968 0.256
Residuals 86 4.1358 0.0481


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 0.863 0.292   10 0.0923 0.338 0.472, 1.3 -0.01
129X1/SvJ m 1.03 0.309   5 0.138 0.299 0.587, 1.39 1.09
AKR/J f 0.709 0.118   5 0.0529 0.167 0.571, 0.857 -0.94
BALB/cByJ f 0.863 0.207   10 0.0655 0.24 0.595, 1.24 -0.01
BALB/cByJ m 0.869 0.134   5 0.0598 0.154 0.71, 1.02 -0.04
C3H/HeJ f 0.824 0.115   5 0.0515 0.14 0.702, 0.984 -0.25
C3H/HeJ m 0.69 0.181   5 0.0809 0.262 0.472, 0.873 -1.28
C57BL/6ByJ f 0.838 0.0989   5 0.0442 0.118 0.758, 1.0 -0.16
C57BL/6ByJ m 0.935 0.16   5 0.0715 0.171 0.714, 1.1 0.42
C57BL/6J f 1.08 0.206   10 0.0651 0.19 0.77, 1.48 1.31
C57BL/6J m 0.88 0.188   5 0.084 0.213 0.615, 1.14 0.04
DBA/1LacJ f 0.835 0.208   5 0.093 0.249 0.631, 1.15 -0.18
DBA/1LacJ m 0.694 0.0717   5 0.0321 0.103 0.623, 0.813 -1.26
NZB/BlNJ f 0.803 0.195   5 0.0871 0.243 0.536, 1.05 -0.37
NZB/BlNJ m 0.775 0.251   5 0.112 0.323 0.544, 1.15 -0.69
PL/J f 0.63 0.18   4 0.0901 0.286 0.409, 0.825 -1.42
PL/J m 0.874 0.177   5 0.079 0.202 0.631, 1.13 0.0
SWR/J f 1.2 0.308   5 0.138 0.257 0.702, 1.49 2.03
SWR/J m 1.12 0.347   5 0.155 0.31 0.865, 1.72 1.71


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 0.8634 0.0693 1.0013 0.7255
129X1/SvJ m 1.0332 0.0981 1.2282 0.8382
BALB/cByJ f 0.8625 0.0693 1.0004 0.7246
BALB/cByJ m 0.8688 0.0981 1.0638 0.6738
C3H/HeJ f 0.8236 0.0981 1.0186 0.6286
C3H/HeJ m 0.6904 0.0981 0.8854 0.4954
C57BL/6ByJ f 0.838 0.0981 1.033 0.643
C57BL/6ByJ m 0.935 0.0981 1.13 0.74
C57BL/6J f 1.0849 0.0693 1.2228 0.947
C57BL/6J m 0.8804 0.0981 1.0754 0.6854
DBA/1LacJ f 0.8346 0.0981 1.0296 0.6396
DBA/1LacJ m 0.6942 0.0981 0.8892 0.4992
NZB/BlNJ f 0.803 0.0981 0.998 0.608
NZB/BlNJ m 0.7752 0.0981 0.9702 0.5802
PL/J f 0.6297 0.1096 0.8477 0.4118
PL/J m 0.8736 0.0981 1.0686 0.6786
SWR/J f 1.1984 0.0981 1.3934 1.0034
SWR/J m 1.1218 0.0981 1.3168 0.9268


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 0.9483 0.0601 1.0677 0.8289
BALB/cByJ both 0.8656 0.0601 0.985 0.7463
C3H/HeJ both 0.757 0.0693 0.8949 0.6191
C57BL/6ByJ both 0.8865 0.0693 1.0244 0.7486
C57BL/6J both 0.9827 0.0601 1.102 0.8633
DBA/1LacJ both 0.7644 0.0693 0.9023 0.6265
NZB/BlNJ both 0.7891 0.0693 0.927 0.6512
PL/J both 0.7517 0.0736 0.8979 0.6055
SWR/J both 1.1601 0.0693 1.298 1.0222




  GWAS USING LINEAR MIXED MODELS