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Project measure / variable:   Schonfeld1   FC

ID, description, units MPD:32332   FC   free cholesterol (plasma)   [mg/dL]  
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Schonfeld1 - free cholesterol (plasma)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means14.3   mg/dL 13.5   mg/dL
Median of the strain means13.0   mg/dL 12.6   mg/dL
SD of the strain means± 5.27 ± 5.90
Coefficient of variation (CV)0.368 0.437
Min–max range of strain means9.30   –   23.8   mg/dL 6.08   –   26.2   mg/dL
Mean sample size per strain6.2   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.1703 1.1703 0.1922 0.6621
strain 8 2645.7955 330.7244 54.3297 < 0.0001
sex:strain 8 157.2685 19.6586 3.2294 0.0029
Residuals 87 529.6 6.0874


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 13.0 2.36   10 0.745 0.181 10.0, 16.8 -0.25
129X1/SvJ m 11.2 1.92   5 0.858 0.171 8.4, 13.2 -0.39
AKR/J f 10.3 3.71   5 1.66 0.36 8.0, 16.8 -0.76
BALB/cByJ f 9.3 3.24   10 1.02 0.348 3.6, 13.9 -0.95
BALB/cByJ m 6.08 2.2   5 0.983 0.362 3.2, 8.4 -1.26
C3H/HeJ f 22.1 4.17   5 1.87 0.189 17.8, 28.2 1.48
C3H/HeJ m 18.2 1.37   5 0.614 0.0757 16.8, 20.0 0.79
C57BL/6ByJ f 9.68 1.63   5 0.731 0.169 8.4, 12.4 -0.88
C57BL/6ByJ m 13.5 0.593   5 0.265 0.0439 12.8, 14.4 0.0
C57BL/6J f 9.4 3.13   10 0.989 0.333 4.0, 14.0 -0.93
C57BL/6J m 8.0 1.7   5 0.759 0.212 5.6, 10.4 -0.93
DBA/1LacJ f 13.0 1.64   5 0.733 0.127 11.2, 15.6 -0.25
DBA/1LacJ m 12.6 0.825   5 0.369 0.0654 12.0, 14.0 -0.15
NZB/BlNJ f 23.8 4.55   5 2.03 0.191 18.4, 28.4 1.8
NZB/BlNJ m 26.2 2.41   5 1.08 0.0918 23.2, 29.2 2.15
PL/J f 17.0 2.01   5 0.9 0.118 14.4, 20.0 0.51
PL/J m 14.2 1.19   5 0.531 0.0838 12.4, 15.6 0.12
SWR/J f 15.6 1.81   5 0.81 0.116 14.4, 18.8 0.24
SWR/J m 11.6 1.41   5 0.632 0.122 10.4, 14.0 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 13.02 0.7802 14.5708 11.4692
129X1/SvJ m 11.2 1.1034 13.3931 9.0069
BALB/cByJ f 9.3 0.7802 10.8508 7.7492
BALB/cByJ m 6.08 1.1034 8.2731 3.8869
C3H/HeJ f 22.08 1.1034 24.2731 19.8869
C3H/HeJ m 18.16 1.1034 20.3531 15.9669
C57BL/6ByJ f 9.68 1.1034 11.8731 7.4869
C57BL/6ByJ m 13.52 1.1034 15.7131 11.3269
C57BL/6J f 9.4 0.7802 10.9508 7.8492
C57BL/6J m 8.0 1.1034 10.1931 5.8069
DBA/1LacJ f 12.96 1.1034 15.1531 10.7669
DBA/1LacJ m 12.6 1.1034 14.7931 10.4069
NZB/BlNJ f 23.84 1.1034 26.0331 21.6469
NZB/BlNJ m 26.24 1.1034 28.4331 24.0469
PL/J f 17.04 1.1034 19.2331 14.8469
PL/J m 14.16 1.1034 16.3531 11.9669
SWR/J f 15.6 1.1034 17.7931 13.4069
SWR/J m 11.6 1.1034 13.7931 9.4069


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 12.11 0.6757 13.453 10.767
BALB/cByJ both 7.69 0.6757 9.033 6.347
C3H/HeJ both 20.12 0.7802 21.6708 18.5692
C57BL/6ByJ both 11.6 0.7802 13.1508 10.0492
C57BL/6J both 8.7 0.6757 10.043 7.357
DBA/1LacJ both 12.78 0.7802 14.3308 11.2292
NZB/BlNJ both 25.04 0.7802 26.5908 23.4892
PL/J both 15.6 0.7802 17.1508 14.0492
SWR/J both 13.6 0.7802 15.1508 12.0492




  GWAS USING LINEAR MIXED MODELS