Project measure / variable:   Schonfeld1   AUC_ITT1

ID, description, units MPD:32318   AUC_ITT1   glucose levels, area under curve, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast)   [AUC]  0 to 60 min  
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
Procedure insulin tolerance
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  STRAIN COMPARISON PLOT
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Schonfeld1 - glucose levels, area under curve, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast) 0 to 60 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means-3460   AUC -3632   AUC
Median of the strain means-3362   AUC -3498   AUC
SD of the strain means± 764 ± 982
Coefficient of variation (CV)-0.221 -0.270
Min–max range of strain means-4524   –   -2454   AUC -4722   –   -1649   AUC
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 130797.3444 130797.3444 0.2391 0.6264
strain 8 51187684.6222 6398460.5778 11.6949 < 0.0001
sex:strain 8 9492387.9556 1186548.4944 2.1687 0.04
Residuals 72 39392188.4 547113.7278


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f -4029.0 474.0   5 212.0 -0.118 -4785.0, -3495.0 -0.75
129X1/SvJ m -4437.0 1071.0   5 479.0 -0.241 -5895.0, -3045.0 -0.82
AKR/J f -2599.0 192.0   5 85.8 -0.0738 -2790.0, -2280.0 1.13
BALB/cByJ f -2790.0 629.0   5 281.0 -0.225 -3690.0, -2070.0 0.88
BALB/cByJ m -1649.0 665.0   5 297.0 -0.403 -2580.0, -750.0 2.02
C3H/HeJ f -3354.0 325.0   5 145.0 -0.0968 -3705.0, -2835.0 0.14
C3H/HeJ m -3498.0 565.0   5 253.0 -0.162 -4470.0, -3075.0 0.14
C57BL/6ByJ f -2454.0 152.0   5 67.8 -0.0618 -2640.0, -2280.0 1.32
C57BL/6ByJ m -3079.0 882.0   5 394.0 -0.287 -4275.0, -2145.0 0.56
C57BL/6J f -4473.0 637.0   5 285.0 -0.142 -5400.0, -3855.0 -1.33
C57BL/6J m -4722.0 1008.0   5 451.0 -0.213 -5700.0, -3255.0 -1.11
DBA/1LacJ f -2982.0 836.0   5 374.0 -0.28 -3615.0, -1605.0 0.63
DBA/1LacJ m -3180.0 900.0   5 402.0 -0.283 -4050.0, -2085.0 0.46
NZB/BlNJ f -3369.0 388.0   5 174.0 -0.115 -3900.0, -2865.0 0.12
NZB/BlNJ m -4494.0 636.0   5 284.0 -0.142 -5250.0, -3645.0 -0.88
PL/J f -4023.0 678.0   5 303.0 -0.168 -5085.0, -3300.0 -0.74
PL/J m -3264.0 1063.0   5 475.0 -0.326 -4725.0, -2190.0 0.37
SWR/J f -4524.0 908.0   5 406.0 -0.201 -5298.0, -3117.0 -1.39
SWR/J m -4362.0 718.0   5 321.0 -0.165 -5295.0, -3495.0 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f -4029.0 330.7911 -3369.58 -4688.42
129X1/SvJ m -4437.0 330.7911 -3777.58 -5096.42
BALB/cByJ f -2790.0 330.7911 -2130.58 -3449.42
BALB/cByJ m -1648.6 330.7911 -989.18 -2308.02
C3H/HeJ f -3354.0 330.7911 -2694.58 -4013.42
C3H/HeJ m -3498.0 330.7911 -2838.58 -4157.42
C57BL/6ByJ f -2454.0 330.7911 -1794.58 -3113.42
C57BL/6ByJ m -3078.6 330.7911 -2419.18 -3738.02
C57BL/6J f -4473.0 330.7911 -3813.58 -5132.42
C57BL/6J m -4722.0 330.7911 -4062.58 -5381.42
DBA/1LacJ f -2982.0 330.7911 -2322.58 -3641.42
DBA/1LacJ m -3180.0 330.7911 -2520.58 -3839.42
NZB/BlNJ f -3369.0 330.7911 -2709.58 -4028.42
NZB/BlNJ m -4494.0 330.7911 -3834.58 -5153.42
PL/J f -4023.0 330.7911 -3363.58 -4682.42
PL/J m -3264.0 330.7911 -2604.58 -3923.42
SWR/J f -4524.0 330.7911 -3864.58 -5183.42
SWR/J m -4362.0 330.7911 -3702.58 -5021.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both -4233.0 233.9046 -3766.7197 -4699.2803
BALB/cByJ both -2219.3 233.9046 -1753.0197 -2685.5803
C3H/HeJ both -3426.0 233.9046 -2959.7197 -3892.2803
C57BL/6ByJ both -2766.3 233.9046 -2300.0197 -3232.5803
C57BL/6J both -4597.5 233.9046 -4131.2197 -5063.7803
DBA/1LacJ both -3081.0 233.9046 -2614.7197 -3547.2803
NZB/BlNJ both -3931.5 233.9046 -3465.2197 -4397.7803
PL/J both -3643.5 233.9046 -3177.2197 -4109.7803
SWR/J both -4443.0 233.9046 -3976.7197 -4909.2803




  GWAS USING LINEAR MIXED MODELS