Phenotype measure

ID, description, units MPD:2936   aortic_lesion   fatty streak aortic lesion size   [µm2]
high-fat diet study
Data set, strains Paigen1   inbred   44 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings


  STRAIN COMPARISON PLOT
width:   ×  height:  pixels

Paigen1 - fatty streak aortic lesion size



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested44 strains42 strains
Mean of the strain means243   µm2 327   µm2
Median of the strain means23.7   µm2 19.8   µm2
SD of the strain means± 528 ± 879
Coefficient of variation (CV)2.17 2.69
Min–max range of strain means0   –   2820   µm2 0   –   4299   µm2
Mean sample size per strain8.8   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 655671.0338 655671.0338 1.5277 0.2169
strain 41 341194330.648 8321812.9426 19.39 < 0.0001
sex:strain 41 31202153.5289 761028.1349 1.7732 0.0026
Residuals 623 267379011.933 429179.7944


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 79.8 239.0   9 79.8 3.0 0.0, 718.0 -0.31
129S1/SvImJ m 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.37
A/J f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
A/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
AKR/J f 44.8 134.0   9 44.8 3.0 0.0, 403.0 -0.38
AKR/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
BALB/cJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
BALB/cJ m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
BPH/2J f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
BPH/2J m 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.37
BPL/1J f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
BPL/1J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
BPN/3J f 121.0 246.0   9 81.8 2.03 0.0, 745.0 -0.23
BPN/3J m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
BTBR T+ Itpr3tf/J f 355.0 583.0   3 337.0 1.64 0.0, 1028.0 0.21
BTBR T+ Itpr3tf/J m 95.1 151.0   8 53.5 1.59 0.0, 390.0 -0.26
BUB/BnJ f 0.0 0.0   3 0.0 0.0 0.0, 0.0 -0.46
C3H/HeJ f 31.2 73.9   9 24.6 2.37 0.0, 221.0 -0.4
C3H/HeJ m 51.8 60.4   4 30.2 1.17 0.0, 114.0 -0.31
C57BL/10J f 118.0 355.0   9 118.0 3.0 0.0, 1065.0 -0.24
C57BL/10J m 41.0 83.8   9 27.9 2.04 0.0, 225.0 -0.32
C57BL/6J f 1505.0 867.0   9 289.0 0.576 423.0, 3335.0 2.39
C57BL/6J m 3428.0 2832.0   6 1156.0 0.826 413.0, 6787.0 3.53
C57BLKS/J f 894.0 1187.0   9 396.0 1.33 0.0, 3670.0 1.23
C57BLKS/J m 1624.0 1709.0   6 698.0 1.05 131.0, 4914.0 1.47
C57BR/cdJ f 521.0 702.0   10 222.0 1.35 0.0, 1698.0 0.53
C57BR/cdJ m 88.9 221.0   9 73.6 2.49 0.0, 666.0 -0.27
C57L/J f 713.0 920.0   9 307.0 1.29 0.0, 2838.0 0.89
C57L/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
C58/J f 2820.0 1824.0   10 577.0 0.647 0.0, 5013.0 4.88
C58/J m 4299.0 3420.0   10 1082.0 0.796 0.0, 10386.0 4.52
CAST/EiJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
CAST/EiJ m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
CBA/J f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
CBA/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
CE/J f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
CE/J m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
CZECHII/EiJ f 0.0 0.0   7 0.0 0.0 0.0, 0.0 -0.46
CZECHII/EiJ m 0.0 0.0   7 0.0 0.0 0.0, 0.0 -0.37
DBA/1J f 164.0 344.0   9 115.0 2.09 0.0, 958.0 -0.15
DBA/1J m 39.6 112.0   8 39.6 2.83 0.0, 317.0 -0.33
DBA/2J f 65.1 135.0   9 45.1 2.08 0.0, 373.0 -0.34
DBA/2J m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
FVB/NJ f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
FVB/NJ m 0.0 0.0   3 0.0 0.0 0.0, 0.0 -0.37
I/LnJ f 328.0 564.0   10 178.0 1.72 0.0, 1413.0 0.16
I/LnJ m 46.2 92.3   9 30.8 2.0 0.0, 229.0 -0.32
KK/HlJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
KK/HlJ m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
LP/J f 20.3 61.0   9 20.3 3.0 0.0, 183.0 -0.42
LP/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
MOLF/EiJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
MOLF/EiJ m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
NOD/ShiLtJ f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
NOD/ShiLtJ m 191.0 340.0   7 129.0 1.78 0.0, 837.0 -0.15
NON/ShiLtJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
NON/ShiLtJ m 54.1 162.0   9 54.1 3.0 0.0, 487.0 -0.31
NZB/BlNJ f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
NZB/BlNJ m 137.0 255.0   8 90.2 1.86 0.0, 585.0 -0.22
NZW/LacJ f 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.46
NZW/LacJ m 102.0 307.0   9 102.0 3.0 0.0, 922.0 -0.26
PERA/EiJ f 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.46
PERA/EiJ m 0.0 0.0   4 0.0 0.0 0.0, 0.0 -0.37
P/J f 93.5 255.0   10 80.7 2.73 0.0, 811.0 -0.28
P/J m 188.0 221.0   9 73.7 1.18 0.0, 669.0 -0.16
PL/J f 29.4 88.3   9 29.4 3.0 0.0, 265.0 -0.4
PL/J m 225.0 389.0   3 225.0 1.73 0.0, 674.0 -0.12
RBF/DnJ f 218.0 257.0   10 81.2 1.18 0.0, 671.0 -0.05
RBF/DnJ m 316.0 424.0   7 160.0 1.34 0.0, 980.0 -0.01
RF/J f 9.78 29.3   9 9.78 3.0 0.0, 88.0 -0.44
RF/J m 0.0 0.0   5 0.0 0.0 0.0, 0.0 -0.37
RIIIS/J f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
RIIIS/J m 127.0 217.0   7 81.9 1.71 0.0, 461.0 -0.23
SEA/GnJ f 696.0 694.0   8 245.0 0.997 0.0, 1784.0 0.86
SEA/GnJ m 280.0 368.0   10 116.0 1.31 0.0, 840.0 -0.05
SJL/J f 470.0 413.0   9 138.0 0.88 0.0, 1022.0 0.43
SJL/J m 710.0 1030.0   9 343.0 1.45 0.0, 2559.0 0.44
SM/J f 1316.0 1297.0   8 459.0 0.986 0.0, 3561.0 2.03
SM/J m 1561.0 1373.0   6 560.0 0.88 0.0, 3504.0 1.4
SPRET/EiJ f 0.0 0.0   7 0.0 0.0 0.0, 0.0 -0.46
SPRET/EiJ m 0.0 0.0   5 0.0 0.0 0.0, 0.0 -0.37
SWR/J f 27.1 81.3   9 27.1 3.0 0.0, 244.0 -0.41
SWR/J m 122.0 212.0   7 80.2 1.73 0.0, 491.0 -0.23
WSB/EiJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
WSB/EiJ m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
YBR/EiJ f 50.6 113.0   5 50.6 2.24 0.0, 253.0 -0.36


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 79.7778 218.3727 508.6136 0.0
129S1/SvImJ m 0.0 218.3727 428.8358 0.0
A/J f 0.0 207.1666 406.8293 0.0
A/J m 0.0 207.1666 406.8293 0.0
AKR/J f 44.7778 218.3727 473.6136 0.0
AKR/J m 0.0 207.1666 406.8293 0.0
BALB/cJ f 0.0 218.3727 428.8358 0.0
BALB/cJ m 0.0 207.1666 406.8293 0.0
BPH/2J f 0.0 207.1666 406.8293 0.0
BPH/2J m 0.0 218.3727 428.8358 0.0
BPL/1J f 0.0 218.3727 428.8358 0.0
BPL/1J m 0.0 207.1666 406.8293 0.0
BPN/3J f 120.6667 218.3727 549.5024 0.0
BPN/3J m 0.0 231.6192 454.849 0.0
BTBR T+ Itpr3tf/J f 354.6667 378.2326 1097.432 0.0
BTBR T+ Itpr3tf/J m 95.125 231.6192 549.974 0.0
C3H/HeJ f 31.2222 218.3727 460.058 0.0
C3H/HeJ m 51.75 327.5591 695.0037 0.0
C57BL/10J f 118.3333 218.3727 547.1691 0.0
C57BL/10J m 41.0 218.3727 469.8358 0.0
C57BL/6J f 1505.0 218.3727 1933.8358 1076.1642
C57BL/6J m 3427.8333 267.4509 3953.0478 2902.6189
C57BLKS/J f 894.0 218.3727 1322.8358 465.1642
C57BLKS/J m 1624.3333 267.4509 2149.5478 1099.1189
C57BR/cdJ f 520.8 207.1666 927.6293 113.9707
C57BR/cdJ m 88.8889 218.3727 517.7247 0.0
C57L/J f 713.1111 218.3727 1141.9469 284.2753
C57L/J m 0.0 207.1666 406.8293 0.0
C58/J f 2819.7 207.1666 3226.5293 2412.8707
C58/J m 4298.6 207.1666 4705.4293 3891.7707
CAST/EiJ f 0.0 218.3727 428.8358 0.0
CAST/EiJ m 0.0 231.6192 454.849 0.0
CBA/J f 0.0 218.3727 428.8358 0.0
CBA/J m 0.0 207.1666 406.8293 0.0
CE/J f 0.0 207.1666 406.8293 0.0
CE/J m 0.0 231.6192 454.849 0.0
CZECHII/EiJ f 0.0 247.6114 486.2541 0.0
CZECHII/EiJ m 0.0 247.6114 486.2541 0.0
DBA/1J f 164.4444 218.3727 593.2802 0.0
DBA/1J m 39.625 231.6192 494.474 0.0
DBA/2J f 65.1111 218.3727 493.9469 0.0
DBA/2J m 0.0 231.6192 454.849 0.0
FVB/NJ f 0.0 207.1666 406.8293 0.0
FVB/NJ m 0.0 378.2326 742.7654 0.0
I/LnJ f 328.0 207.1666 734.8293 0.0
I/LnJ m 46.2222 218.3727 475.058 0.0
KK/HlJ f 0.0 218.3727 428.8358 0.0
KK/HlJ m 0.0 231.6192 454.849 0.0
LP/J f 20.3333 218.3727 449.1691 0.0
LP/J m 0.0 207.1666 406.8293 0.0
MOLF/EiJ f 0.0 218.3727 428.8358 0.0
MOLF/EiJ m 0.0 207.1666 406.8293 0.0
NOD/ShiLtJ f 0.0 207.1666 406.8293 0.0
NOD/ShiLtJ m 191.0 247.6114 677.2541 0.0
NON/ShiLtJ f 0.0 218.3727 428.8358 0.0
NON/ShiLtJ m 54.1111 218.3727 482.9469 0.0
NZB/BlNJ f 0.0 207.1666 406.8293 0.0
NZB/BlNJ m 137.375 231.6192 592.224 0.0
NZW/LacJ f 0.0 231.6192 454.849 0.0
NZW/LacJ m 102.4444 218.3727 531.2802 0.0
PERA/EiJ f 0.0 231.6192 454.849 0.0
PERA/EiJ m 0.0 327.5591 643.2537 0.0
P/J f 93.5 207.1666 500.3293 0.0
P/J m 187.8889 218.3727 616.7247 0.0
PL/J f 29.4444 218.3727 458.2802 0.0
PL/J m 224.6667 378.2326 967.432 0.0
RBF/DnJ f 218.0 207.1666 624.8293 0.0
RBF/DnJ m 315.7143 247.6114 801.9683 0.0
RF/J f 9.7778 218.3727 438.6136 0.0
RF/J m 0.0 292.9777 575.3436 0.0
RIIIS/J f 0.0 218.3727 428.8358 0.0
RIIIS/J m 126.7143 247.6114 612.9683 0.0
SEA/GnJ f 696.125 231.6192 1150.974 241.276
SEA/GnJ m 280.4 207.1666 687.2293 0.0
SJL/J f 469.6667 218.3727 898.5024 40.8309
SJL/J m 710.0 218.3727 1138.8358 281.1642
SM/J f 1315.75 231.6192 1770.599 860.901
SM/J m 1560.6667 267.4509 2085.8811 1035.4522
SPRET/EiJ f 0.0 247.6114 486.2541 0.0
SPRET/EiJ m 0.0 292.9777 575.3436 0.0
SWR/J f 27.1111 218.3727 455.9469 0.0
SWR/J m 122.4286 247.6114 608.6826 0.0
WSB/EiJ f 0.0 218.3727 428.8358 0.0
WSB/EiJ m 0.0 207.1666 406.8293 0.0


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 39.8889 154.4128 343.1216 0.0
A/J both 0.0 146.4889 287.6718 0.0
AKR/J both 22.3889 150.503 317.9436 0.0
BALB/cJ both 0.0 150.503 295.5547 0.0
BPH/2J both 0.0 150.503 295.5547 0.0
BPL/1J both 0.0 150.503 295.5547 0.0
BPN/3J both 60.3333 159.1651 372.8984 0.0
BTBR T+ Itpr3tf/J both 224.8958 221.7585 660.3806 0.0
C3H/HeJ both 41.4861 196.8385 428.0335 0.0
C57BL/10J both 79.6667 154.4128 382.8994 0.0
C57BL/6J both 2466.4167 172.6388 2805.4411 2127.3922
C57BLKS/J both 1259.1667 172.6388 1598.1911 920.1422
C57BR/cdJ both 304.8444 150.503 600.3991 9.2898
C57L/J both 356.5556 150.503 652.1102 61.0009
C58/J both 3559.15 146.4889 3846.8218 3271.4782
CAST/EiJ both 0.0 159.1651 312.5651 0.0
CBA/J both 0.0 150.503 295.5547 0.0
CE/J both 0.0 155.3749 305.122 0.0
CZECHII/EiJ both 0.0 175.0877 343.8335 0.0
DBA/1J both 102.0347 159.1651 414.5998 0.0
DBA/2J both 32.5556 159.1651 345.1207 0.0
FVB/NJ both 0.0 215.6258 423.4414 0.0
I/LnJ both 187.1111 150.503 482.6658 0.0
KK/HlJ both 0.0 159.1651 312.5651 0.0
LP/J both 10.1667 150.503 305.7213 0.0
MOLF/EiJ both 0.0 150.503 295.5547 0.0
NOD/ShiLtJ both 95.5 161.4229 412.4989 0.0
NON/ShiLtJ both 27.0556 154.4128 330.2882 0.0
NZB/BlNJ both 68.6875 155.3749 373.8095 0.0
NZW/LacJ both 51.2222 159.1651 363.7873 0.0
PERA/EiJ both 0.0 200.5881 393.9108 0.0
P/J both 140.6944 150.503 436.2491 0.0
PL/J both 127.0556 218.3727 555.8913 0.0
RBF/DnJ both 266.8571 161.4229 583.856 0.0
RF/J both 4.8889 182.7037 363.6786 0.0
RIIIS/J both 63.3571 165.0743 387.5265 0.0
SEA/GnJ both 488.2625 155.3749 793.3845 183.1405
SJL/J both 589.8333 154.4128 893.066 286.6006
SM/J both 1438.2083 176.9021 1785.605 1090.8117
SPRET/EiJ both 0.0 191.799 376.6508 0.0
SWR/J both 74.7698 165.0743 398.9392 0.0
WSB/EiJ both 0.0 150.503 295.5547 0.0