Phenotype measure:   Paigen1   aortic_lesion

ID, description, units MPD:2936   aortic_lesion   fatty streak aortic lesion size   [µm2]
high-fat diet study
Data set, strains Paigen1   inbred   44 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings


  STRAIN COMPARISON PLOT
width:   ×  height:  pixels

Paigen1 - fatty streak aortic lesion size



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested44 strains42 strains
Mean of the strain means243   µm2 327   µm2
Median of the strain means23.7   µm2 19.8   µm2
SD of the strain means± 528 ± 879
Coefficient of variation (CV)2.17 2.69
Min–max range of strain means0   –   2820   µm2 0   –   4299   µm2
Mean sample size per strain8.8   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 655671.0338 655671.0338 1.5277 0.2169
strain 41 341194330.6476 8321812.9426 19.39 < 0.0001
sex:strain 41 31202153.5289 761028.1349 1.7732 0.0026
Residuals 623 267379011.9325 429179.7944


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 79.8 239.0   9 79.8 3.0 0.0, 718.0 -0.31
129S1/SvImJ m 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.37
A/J f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
A/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
AKR/J f 44.8 134.0   9 44.8 3.0 0.0, 403.0 -0.38
AKR/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
BALB/cJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
BALB/cJ m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
BPH/2J f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
BPH/2J m 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.37
BPL/1J f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
BPL/1J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
BPN/3J f 121.0 246.0   9 81.8 2.03 0.0, 745.0 -0.23
BPN/3J m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
BTBR T+ Itpr3tf/J f 355.0 583.0   3 337.0 1.64 0.0, 1028.0 0.21
BTBR T+ Itpr3tf/J m 95.1 151.0   8 53.5 1.59 0.0, 390.0 -0.26
BUB/BnJ f 0.0 0.0   3 0.0 0.0 0.0, 0.0 -0.46
C3H/HeJ f 31.2 73.9   9 24.6 2.37 0.0, 221.0 -0.4
C3H/HeJ m 51.8 60.4   4 30.2 1.17 0.0, 114.0 -0.31
C57BL/10J f 118.0 355.0   9 118.0 3.0 0.0, 1065.0 -0.24
C57BL/10J m 41.0 83.8   9 27.9 2.04 0.0, 225.0 -0.32
C57BL/6J f 1505.0 867.0   9 289.0 0.576 423.0, 3335.0 2.39
C57BL/6J m 3428.0 2832.0   6 1156.0 0.826 413.0, 6787.0 3.53
C57BLKS/J f 894.0 1187.0   9 396.0 1.33 0.0, 3670.0 1.23
C57BLKS/J m 1624.0 1709.0   6 698.0 1.05 131.0, 4914.0 1.47
C57BR/cdJ f 521.0 702.0   10 222.0 1.35 0.0, 1698.0 0.53
C57BR/cdJ m 88.9 221.0   9 73.6 2.49 0.0, 666.0 -0.27
C57L/J f 713.0 920.0   9 307.0 1.29 0.0, 2838.0 0.89
C57L/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
C58/J f 2820.0 1824.0   10 577.0 0.647 0.0, 5013.0 4.88
C58/J m 4299.0 3420.0   10 1082.0 0.796 0.0, 10386.0 4.52
CAST/EiJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
CAST/EiJ m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
CBA/J f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
CBA/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
CE/J f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
CE/J m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
CZECHII/EiJ f 0.0 0.0   7 0.0 0.0 0.0, 0.0 -0.46
CZECHII/EiJ m 0.0 0.0   7 0.0 0.0 0.0, 0.0 -0.37
DBA/1J f 164.0 344.0   9 115.0 2.09 0.0, 958.0 -0.15
DBA/1J m 39.6 112.0   8 39.6 2.83 0.0, 317.0 -0.33
DBA/2J f 65.1 135.0   9 45.1 2.08 0.0, 373.0 -0.34
DBA/2J m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
FVB/NJ f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
FVB/NJ m 0.0 0.0   3 0.0 0.0 0.0, 0.0 -0.37
I/LnJ f 328.0 564.0   10 178.0 1.72 0.0, 1413.0 0.16
I/LnJ m 46.2 92.3   9 30.8 2.0 0.0, 229.0 -0.32
KK/HlJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
KK/HlJ m 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.37
LP/J f 20.3 61.0   9 20.3 3.0 0.0, 183.0 -0.42
LP/J m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
MOLF/EiJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
MOLF/EiJ m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
NOD/ShiLtJ f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
NOD/ShiLtJ m 191.0 340.0   7 129.0 1.78 0.0, 837.0 -0.15
NON/ShiLtJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
NON/ShiLtJ m 54.1 162.0   9 54.1 3.0 0.0, 487.0 -0.31
NZB/BlNJ f 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.46
NZB/BlNJ m 137.0 255.0   8 90.2 1.86 0.0, 585.0 -0.22
NZW/LacJ f 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.46
NZW/LacJ m 102.0 307.0   9 102.0 3.0 0.0, 922.0 -0.26
PERA/EiJ f 0.0 0.0   8 0.0 0.0 0.0, 0.0 -0.46
PERA/EiJ m 0.0 0.0   4 0.0 0.0 0.0, 0.0 -0.37
P/J f 93.5 255.0   10 80.7 2.73 0.0, 811.0 -0.28
P/J m 188.0 221.0   9 73.7 1.18 0.0, 669.0 -0.16
PL/J f 29.4 88.3   9 29.4 3.0 0.0, 265.0 -0.4
PL/J m 225.0 389.0   3 225.0 1.73 0.0, 674.0 -0.12
RBF/DnJ f 218.0 257.0   10 81.2 1.18 0.0, 671.0 -0.05
RBF/DnJ m 316.0 424.0   7 160.0 1.34 0.0, 980.0 -0.01
RF/J f 9.78 29.3   9 9.78 3.0 0.0, 88.0 -0.44
RF/J m 0.0 0.0   5 0.0 0.0 0.0, 0.0 -0.37
RIIIS/J f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
RIIIS/J m 127.0 217.0   7 81.9 1.71 0.0, 461.0 -0.23
SEA/GnJ f 696.0 694.0   8 245.0 0.997 0.0, 1784.0 0.86
SEA/GnJ m 280.0 368.0   10 116.0 1.31 0.0, 840.0 -0.05
SJL/J f 470.0 413.0   9 138.0 0.88 0.0, 1022.0 0.43
SJL/J m 710.0 1030.0   9 343.0 1.45 0.0, 2559.0 0.44
SM/J f 1316.0 1297.0   8 459.0 0.986 0.0, 3561.0 2.03
SM/J m 1561.0 1373.0   6 560.0 0.88 0.0, 3504.0 1.4
SPRET/EiJ f 0.0 0.0   7 0.0 0.0 0.0, 0.0 -0.46
SPRET/EiJ m 0.0 0.0   5 0.0 0.0 0.0, 0.0 -0.37
SWR/J f 27.1 81.3   9 27.1 3.0 0.0, 244.0 -0.41
SWR/J m 122.0 212.0   7 80.2 1.73 0.0, 491.0 -0.23
WSB/EiJ f 0.0 0.0   9 0.0 0.0 0.0, 0.0 -0.46
WSB/EiJ m 0.0 0.0   10 0.0 0.0 0.0, 0.0 -0.37
YBR/EiJ f 50.6 113.0   5 50.6 2.24 0.0, 253.0 -0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 79.7778 218.3727 508.6136 -349.058
129S1/SvImJ m 0.0 218.3727 428.8358 -428.8358
A/J f 0.0 207.1666 406.8293 -406.8293
A/J m 0.0 207.1666 406.8293 -406.8293
AKR/J f 44.7778 218.3727 473.6136 -384.058
AKR/J m 0.0 207.1666 406.8293 -406.8293
BALB/cJ f 0.0 218.3727 428.8358 -428.8358
BALB/cJ m 0.0 207.1666 406.8293 -406.8293
BPH/2J f 0.0 207.1666 406.8293 -406.8293
BPH/2J m 0.0 218.3727 428.8358 -428.8358
BPL/1J f 0.0 218.3727 428.8358 -428.8358
BPL/1J m 0.0 207.1666 406.8293 -406.8293
BPN/3J f 120.6667 218.3727 549.5024 -308.1691
BPN/3J m 0.0 231.6192 454.849 -454.849
BTBR T+ Itpr3tf/J f 354.6667 378.2326 1097.432 -388.0987
BTBR T+ Itpr3tf/J m 95.125 231.6192 549.974 -359.724
C3H/HeJ f 31.2222 218.3727 460.058 -397.6136
C3H/HeJ m 51.75 327.5591 695.0037 -591.5037
C57BL/10J f 118.3333 218.3727 547.1691 -310.5024
C57BL/10J m 41.0 218.3727 469.8358 -387.8358
C57BL/6J f 1505.0 218.3727 1933.8358 1076.1642
C57BL/6J m 3427.8333 267.4509 3953.0478 2902.6189
C57BLKS/J f 894.0 218.3727 1322.8358 465.1642
C57BLKS/J m 1624.3333 267.4509 2149.5478 1099.1189
C57BR/cdJ f 520.8 207.1666 927.6293 113.9707
C57BR/cdJ m 88.8889 218.3727 517.7247 -339.9469
C57L/J f 713.1111 218.3727 1141.9469 284.2753
C57L/J m 0.0 207.1666 406.8293 -406.8293
C58/J f 2819.7 207.1666 3226.5293 2412.8707
C58/J m 4298.6 207.1666 4705.4293 3891.7707
CAST/EiJ f 0.0 218.3727 428.8358 -428.8358
CAST/EiJ m 0.0 231.6192 454.849 -454.849
CBA/J f 0.0 218.3727 428.8358 -428.8358
CBA/J m 0.0 207.1666 406.8293 -406.8293
CE/J f 0.0 207.1666 406.8293 -406.8293
CE/J m 0.0 231.6192 454.849 -454.849
CZECHII/EiJ f 0.0 247.6114 486.2541 -486.2541
CZECHII/EiJ m 0.0 247.6114 486.2541 -486.2541
DBA/1J f 164.4444 218.3727 593.2802 -264.3913
DBA/1J m 39.625 231.6192 494.474 -415.224
DBA/2J f 65.1111 218.3727 493.9469 -363.7247
DBA/2J m 0.0 231.6192 454.849 -454.849
FVB/NJ f 0.0 207.1666 406.8293 -406.8293
FVB/NJ m 0.0 378.2326 742.7654 -742.7654
I/LnJ f 328.0 207.1666 734.8293 -78.8293
I/LnJ m 46.2222 218.3727 475.058 -382.6136
KK/HlJ f 0.0 218.3727 428.8358 -428.8358
KK/HlJ m 0.0 231.6192 454.849 -454.849
LP/J f 20.3333 218.3727 449.1691 -408.5024
LP/J m 0.0 207.1666 406.8293 -406.8293
MOLF/EiJ f 0.0 218.3727 428.8358 -428.8358
MOLF/EiJ m 0.0 207.1666 406.8293 -406.8293
NOD/ShiLtJ f 0.0 207.1666 406.8293 -406.8293
NOD/ShiLtJ m 191.0 247.6114 677.2541 -295.2541
NON/ShiLtJ f 0.0 218.3727 428.8358 -428.8358
NON/ShiLtJ m 54.1111 218.3727 482.9469 -374.7247
NZB/BlNJ f 0.0 207.1666 406.8293 -406.8293
NZB/BlNJ m 137.375 231.6192 592.224 -317.474
NZW/LacJ f 0.0 231.6192 454.849 -454.849
NZW/LacJ m 102.4444 218.3727 531.2802 -326.3913
PERA/EiJ f 0.0 231.6192 454.849 -454.849
PERA/EiJ m 0.0 327.5591 643.2537 -643.2537
P/J f 93.5 207.1666 500.3293 -313.3293
P/J m 187.8889 218.3727 616.7247 -240.9469
PL/J f 29.4444 218.3727 458.2802 -399.3913
PL/J m 224.6667 378.2326 967.432 -518.0987
RBF/DnJ f 218.0 207.1666 624.8293 -188.8293
RBF/DnJ m 315.7143 247.6114 801.9683 -170.5398
RF/J f 9.7778 218.3727 438.6136 -419.058
RF/J m 0.0 292.9777 575.3436 -575.3436
RIIIS/J f 0.0 218.3727 428.8358 -428.8358
RIIIS/J m 126.7143 247.6114 612.9683 -359.5398
SEA/GnJ f 696.125 231.6192 1150.974 241.276
SEA/GnJ m 280.4 207.1666 687.2293 -126.4293
SJL/J f 469.6667 218.3727 898.5024 40.8309
SJL/J m 710.0 218.3727 1138.8358 281.1642
SM/J f 1315.75 231.6192 1770.599 860.901
SM/J m 1560.6667 267.4509 2085.8811 1035.4522
SPRET/EiJ f 0.0 247.6114 486.2541 -486.2541
SPRET/EiJ m 0.0 292.9777 575.3436 -575.3436
SWR/J f 27.1111 218.3727 455.9469 -401.7247
SWR/J m 122.4286 247.6114 608.6826 -363.8255
WSB/EiJ f 0.0 218.3727 428.8358 -428.8358
WSB/EiJ m 0.0 207.1666 406.8293 -406.8293


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 39.8889 154.4128 343.1216 -263.3438
A/J both 0.0 146.4889 287.6718 -287.6718
AKR/J both 22.3889 150.503 317.9436 -273.1658
BALB/cJ both 0.0 150.503 295.5547 -295.5547
BPH/2J both 0.0 150.503 295.5547 -295.5547
BPL/1J both 0.0 150.503 295.5547 -295.5547
BPN/3J both 60.3333 159.1651 372.8984 -252.2318
BTBR T+ Itpr3tf/J both 224.8958 221.7585 660.3806 -210.589
C3H/HeJ both 41.4861 196.8385 428.0335 -345.0612
C57BL/10J both 79.6667 154.4128 382.8994 -223.566
C57BL/6J both 2466.4167 172.6388 2805.4411 2127.3922
C57BLKS/J both 1259.1667 172.6388 1598.1911 920.1422
C57BR/cdJ both 304.8444 150.503 600.3991 9.2898
C57L/J both 356.5556 150.503 652.1102 61.0009
C58/J both 3559.15 146.4889 3846.8218 3271.4782
CAST/EiJ both 0.0 159.1651 312.5651 -312.5651
CBA/J both 0.0 150.503 295.5547 -295.5547
CE/J both 0.0 155.3749 305.122 -305.122
CZECHII/EiJ both 0.0 175.0877 343.8335 -343.8335
DBA/1J both 102.0347 159.1651 414.5998 -210.5304
DBA/2J both 32.5556 159.1651 345.1207 -280.0095
FVB/NJ both 0.0 215.6258 423.4414 -423.4414
I/LnJ both 187.1111 150.503 482.6658 -108.4436
KK/HlJ both 0.0 159.1651 312.5651 -312.5651
LP/J both 10.1667 150.503 305.7213 -285.388
MOLF/EiJ both 0.0 150.503 295.5547 -295.5547
NOD/ShiLtJ both 95.5 161.4229 412.4989 -221.4989
NON/ShiLtJ both 27.0556 154.4128 330.2882 -276.1771
NZB/BlNJ both 68.6875 155.3749 373.8095 -236.4345
NZW/LacJ both 51.2222 159.1651 363.7873 -261.3429
PERA/EiJ both 0.0 200.5881 393.9108 -393.9108
P/J both 140.6944 150.503 436.2491 -154.8602
PL/J both 127.0556 218.3727 555.8913 -301.7802
RBF/DnJ both 266.8571 161.4229 583.856 -50.1417
RF/J both 4.8889 182.7037 363.6786 -353.9009
RIIIS/J both 63.3571 165.0743 387.5265 -260.8122
SEA/GnJ both 488.2625 155.3749 793.3845 183.1405
SJL/J both 589.8333 154.4128 893.066 286.6006
SM/J both 1438.2083 176.9021 1785.605 1090.8117
SPRET/EiJ both 0.0 191.799 376.6508 -376.6508
SWR/J both 74.7698 165.0743 398.9392 -249.3995
WSB/EiJ both 0.0 150.503 295.5547 -295.5547