Project measure / variable:   Paigen1   macrovacs

ID, description, units MPD:2931   macrovacs   liver macrovacuoles (score: 0-4)   [score]  
high-fat diet study
Data set, strains Paigen1   inbred   43 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen1 - liver macrovacuoles (score: 0-4)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains40 strains
Mean of the strain means0.250   score 0.317   score
Median of the strain means0   score 0   score
SD of the strain means± 0.456 ± 0.583
Coefficient of variation (CV)1.82 1.84
Min–max range of strain means0   –   1.67   score 0   –   2.00   score
Mean sample size per strain3.0   mice 2.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4907 0.4907 6.4836 0.0118
strain 39 51.9823 1.3329 17.6117 < 0.0001
sex:strain 39 11.2677 0.2889 3.8175 < 0.0001
Residuals 159 12.0333 0.0757


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0 0.0   3 0.0 0.0 -0.55
129S1/SvImJ m 0.0 0.0   3 0.0 0.0 -0.54
A/J f 0.0 0.0   3 0.0 0.0 -0.55
A/J m 0.0 0.0   3 0.0 0.0 -0.54
AKR/J f 0.667 0.577   3 0.333 0.866 0.92
AKR/J m 1.33 0.577   3 0.333 0.433 1.0, 2.0 1.74
BALB/cJ f 0.0 0.0   3 0.0 0.0 -0.55
BALB/cJ m 0.0 0.0   3 0.0 0.0 -0.54
BPH/2J f 0.0 0.0   3 0.0 0.0 -0.55
BPH/2J m 0.0 0.0   3 0.0 0.0 -0.54
BPL/1J f 1.0 0.0   3 0.0 0.0 1.0, 1.0 1.65
BPL/1J m 1.67 0.577   3 0.333 0.346 1.0, 2.0 2.32
BPN/3J f 0.0 0.0   3 0.0 0.0 -0.55
BPN/3J m 0.0 0.0   3 0.0 0.0 -0.54
BTBR T+ Itpr3tf/J f 0.0 0.0   3 0.0 0.0 -0.55
BTBR T+ Itpr3tf/J m 0.0 0.0   3 0.0 0.0 -0.54
C3H/HeJ f 0.0 0.0   3 0.0 0.0 -0.55
C3H/HeJ m 0.0 0.0   3 0.0 0.0 -0.54
C57BL/10J f 0.0 0.0   3 0.0 0.0 -0.55
C57BL/10J m 0.0 0.0   3 0.0 0.0 -0.54
C57BL/6J f 0.0 0.0   3 0.0 0.0 -0.55
C57BL/6J m 0.0 0.0   3 0.0 0.0 -0.54
C57BLKS/J f 0.0 0.0   3 0.0 0.0 -0.55
C57BLKS/J m 0.0 0.0   3 0.0 0.0 -0.54
C57BR/cdJ f 0.0 0.0   3 0.0 0.0 -0.55
C57BR/cdJ m 0.0 0.0   3 0.0 0.0 -0.54
C57L/J f 0.0 0.0   3 0.0 0.0 -0.55
C57L/J m 0.0 0.0   3 0.0 0.0 -0.54
C58/J f 0.0 0.0   3 0.0 0.0 -0.55
C58/J m 0.0 0.0   3 0.0 0.0 -0.54
CAST/EiJ f 0.4 0.548   5 0.245 1.37 0.33
CAST/EiJ m 0.333 0.577   3 0.333 1.73 0.03
CBA/J f 1.0 0.0   3 0.0 0.0 1.0, 1.0 1.65
CBA/J m 0.333 0.577   3 0.333 1.73 0.03
CE/J f 0.0 0.0   3 0.0 0.0 -0.55
CE/J m 0.0 0.0   3 0.0 0.0 -0.54
CZECHII/EiJ f 1.67 0.577   3 0.333 0.346 1.0, 2.0 3.12
CZECHII/EiJ m 1.5 0.707   2   0.5 0.471 1.0, 2.0 2.03
DBA/1J f 0.0 0.0   3 0.0 0.0 -0.55
DBA/1J m 0.0 0.0   3 0.0 0.0 -0.54
DBA/2J f 0.0 0.0   3 0.0 0.0 -0.55
DBA/2J m 0.0 0.0   3 0.0 0.0 -0.54
FVB/NJ f 0.0 0.0   2   0.0 0.0 -0.55
FVB/NJ m 0.0 0.0   2   0.0 0.0 -0.54
I/LnJ f 0.0 0.0   3 0.0 0.0 -0.55
KK/HlJ f 1.67 0.577   3 0.333 0.346 1.0, 2.0 3.12
KK/HlJ m 1.5 0.577   4 0.289 0.385 1.0, 2.0 2.03
LP/J f 0.0 0.0   3 0.0 0.0 -0.55
LP/J m 1.0 0.0   3 0.0 0.0 1.0, 1.0 1.17
MOLF/EiJ f 1.0 0.0   3 0.0 0.0 1.0, 1.0 1.65
NOD/ShiLtJ f 0.333 0.577   3 0.333 1.73 0.18
NOD/ShiLtJ m 0.0 0.0   3 0.0 0.0 -0.54
NON/ShiLtJ f 0.0 0.0   3 0.0 0.0 -0.55
NON/ShiLtJ m 0.0 0.0   3 0.0 0.0 -0.54
NZB/BlNJ f 0.0 0.0   3 0.0 0.0 -0.55
NZB/BlNJ m 0.0 0.0   3 0.0 0.0 -0.54
NZW/LacJ f 0.0 0.0   3 0.0 0.0 -0.55
NZW/LacJ m 0.0 0.0   3 0.0 0.0 -0.54
PERA/EiJ f 0.0 0.0   3 0.0 0.0 -0.55
PERA/EiJ m 0.0 0.0   2   0.0 0.0 -0.54
P/J f 1.0 0.0   3 0.0 0.0 1.0, 1.0 1.65
P/J m 1.0 0.0   3 0.0 0.0 1.0, 1.0 1.17
PL/J f 0.0 0.0   3 0.0 0.0 -0.55
PL/J m 1.0 1.0   3 0.577 1.0 1.17
RBF/DnJ f 0.0 0.0   3 0.0 0.0 -0.55
RBF/DnJ m 0.0 0.0   3 0.0 0.0 -0.54
RF/J f 0.333 0.577   3 0.333 1.73 0.18
RF/J m 2.0 0.0   3 0.0 0.0 2.0, 2.0 2.89
RIIIS/J f 0.0 0.0   3 0.0 0.0 -0.55
RIIIS/J m 1.0 0.0   3 0.0 0.0 1.0, 1.0 1.17
SEA/GnJ f 0.0 0.0   3 0.0 0.0 -0.55
SEA/GnJ m 0.0 0.0   3 0.0 0.0 -0.54
SJL/J f 0.0 0.0   3 0.0 0.0 -0.55
SJL/J m 0.0 0.0   3 0.0 0.0 -0.54
SM/J f 0.333 0.577   3 0.333 1.73 0.18
SM/J m 0.0 0.0   3 0.0 0.0 -0.54
SPRET/EiJ f 0.667 0.577   3 0.333 0.866 0.92
SPRET/EiJ m 0.0 0.0   3 0.0 0.0 -0.54
SWR/J f 0.0 0.0   3 0.0 0.0 -0.55
SWR/J m 0.0 0.0   3 0.0 0.0 -0.54
WSB/EiJ f 0.0 0.0   3 0.0 0.0 -0.55
WSB/EiJ m 0.0 0.0   3 0.0 0.0 -0.54
YBR/EiJ f 0.667 0.577   3 0.333 0.866 0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0 0.1588 0.3137 -0.3137
129S1/SvImJ m 0.0 0.1588 0.3137 -0.3137
A/J f 0.0 0.1588 0.3137 -0.3137
A/J m 0.0 0.1588 0.3137 -0.3137
AKR/J f 0.6667 0.1588 0.9804 0.353
AKR/J m 1.3333 0.1588 1.647 1.0196
BALB/cJ f 0.0 0.1588 0.3137 -0.3137
BALB/cJ m 0.0 0.1588 0.3137 -0.3137
BPH/2J f 0.0 0.1588 0.3137 -0.3137
BPH/2J m 0.0 0.1588 0.3137 -0.3137
BPL/1J f 1.0 0.1588 1.3137 0.6863
BPL/1J m 1.6667 0.1588 1.9804 1.353
BPN/3J f 0.0 0.1588 0.3137 -0.3137
BPN/3J m 0.0 0.1588 0.3137 -0.3137
BTBR T+ Itpr3tf/J f 0.0 0.1588 0.3137 -0.3137
BTBR T+ Itpr3tf/J m 0.0 0.1588 0.3137 -0.3137
C3H/HeJ f 0.0 0.1588 0.3137 -0.3137
C3H/HeJ m 0.0 0.1588 0.3137 -0.3137
C57BL/10J f 0.0 0.1588 0.3137 -0.3137
C57BL/10J m 0.0 0.1588 0.3137 -0.3137
C57BL/6J f 0.0 0.1588 0.3137 -0.3137
C57BL/6J m 0.0 0.1588 0.3137 -0.3137
C57BLKS/J f 0.0 0.1588 0.3137 -0.3137
C57BLKS/J m 0.0 0.1588 0.3137 -0.3137
C57BR/cdJ f 0.0 0.1588 0.3137 -0.3137
C57BR/cdJ m 0.0 0.1588 0.3137 -0.3137
C57L/J f 0.0 0.1588 0.3137 -0.3137
C57L/J m 0.0 0.1588 0.3137 -0.3137
C58/J f 0.0 0.1588 0.3137 -0.3137
C58/J m 0.0 0.1588 0.3137 -0.3137
CAST/EiJ f 0.4 0.123 0.643 0.157
CAST/EiJ m 0.3333 0.1588 0.647 0.0196
CBA/J f 1.0 0.1588 1.3137 0.6863
CBA/J m 0.3333 0.1588 0.647 0.0196
CE/J f 0.0 0.1588 0.3137 -0.3137
CE/J m 0.0 0.1588 0.3137 -0.3137
CZECHII/EiJ f 1.6667 0.1588 1.9804 1.353
CZECHII/EiJ m 1.5 0.1945 1.8842 1.1158
DBA/1J f 0.0 0.1588 0.3137 -0.3137
DBA/1J m 0.0 0.1588 0.3137 -0.3137
DBA/2J f 0.0 0.1588 0.3137 -0.3137
DBA/2J m 0.0 0.1588 0.3137 -0.3137
FVB/NJ f 0.0 0.1945 0.3842 -0.3842
FVB/NJ m 0.0 0.1945 0.3842 -0.3842
KK/HlJ f 1.6667 0.1588 1.9804 1.353
KK/HlJ m 1.5 0.1376 1.7717 1.2283
LP/J f 0.0 0.1588 0.3137 -0.3137
LP/J m 1.0 0.1588 1.3137 0.6863
NOD/ShiLtJ f 0.3333 0.1588 0.647 0.0196
NOD/ShiLtJ m 0.0 0.1588 0.3137 -0.3137
NON/ShiLtJ f 0.0 0.1588 0.3137 -0.3137
NON/ShiLtJ m 0.0 0.1588 0.3137 -0.3137
NZB/BlNJ f 0.0 0.1588 0.3137 -0.3137
NZB/BlNJ m 0.0 0.1588 0.3137 -0.3137
NZW/LacJ f 0.0 0.1588 0.3137 -0.3137
NZW/LacJ m 0.0 0.1588 0.3137 -0.3137
PERA/EiJ f 0.0 0.1588 0.3137 -0.3137
PERA/EiJ m 0.0 0.1945 0.3842 -0.3842
P/J f 1.0 0.1588 1.3137 0.6863
P/J m 1.0 0.1588 1.3137 0.6863
PL/J f 0.0 0.1588 0.3137 -0.3137
PL/J m 1.0 0.1588 1.3137 0.6863
RBF/DnJ f 0.0 0.1588 0.3137 -0.3137
RBF/DnJ m 0.0 0.1588 0.3137 -0.3137
RF/J f 0.3333 0.1588 0.647 0.0196
RF/J m 2.0 0.1588 2.3137 1.6863
RIIIS/J f 0.0 0.1588 0.3137 -0.3137
RIIIS/J m 1.0 0.1588 1.3137 0.6863
SEA/GnJ f 0.0 0.1588 0.3137 -0.3137
SEA/GnJ m 0.0 0.1588 0.3137 -0.3137
SJL/J f 0.0 0.1588 0.3137 -0.3137
SJL/J m 0.0 0.1588 0.3137 -0.3137
SM/J f 0.3333 0.1588 0.647 0.0196
SM/J m 0.0 0.1588 0.3137 -0.3137
SPRET/EiJ f 0.6667 0.1588 0.9804 0.353
SPRET/EiJ m 0.0 0.1588 0.3137 -0.3137
SWR/J f 0.0 0.1588 0.3137 -0.3137
SWR/J m 0.0 0.1588 0.3137 -0.3137
WSB/EiJ f 0.0 0.1588 0.3137 -0.3137
WSB/EiJ m 0.0 0.1588 0.3137 -0.3137


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0 0.1123 0.2218 -0.2218
A/J both 0.0 0.1123 0.2218 -0.2218
AKR/J both 1.0 0.1123 1.2218 0.7782
BALB/cJ both 0.0 0.1123 0.2218 -0.2218
BPH/2J both 0.0 0.1123 0.2218 -0.2218
BPL/1J both 1.3333 0.1123 1.5551 1.1115
BPN/3J both 0.0 0.1123 0.2218 -0.2218
BTBR T+ Itpr3tf/J both 0.0 0.1123 0.2218 -0.2218
C3H/HeJ both 0.0 0.1123 0.2218 -0.2218
C57BL/10J both 0.0 0.1123 0.2218 -0.2218
C57BL/6J both 0.0 0.1123 0.2218 -0.2218
C57BLKS/J both 0.0 0.1123 0.2218 -0.2218
C57BR/cdJ both 0.0 0.1123 0.2218 -0.2218
C57L/J both 0.0 0.1123 0.2218 -0.2218
C58/J both 0.0 0.1123 0.2218 -0.2218
CAST/EiJ both 0.3667 0.1005 0.5651 0.1683
CBA/J both 0.6667 0.1123 0.8885 0.4449
CE/J both 0.0 0.1123 0.2218 -0.2218
CZECHII/EiJ both 1.5833 0.1256 1.8313 1.3353
DBA/1J both 0.0 0.1123 0.2218 -0.2218
DBA/2J both 0.0 0.1123 0.2218 -0.2218
FVB/NJ both 0.0 0.1376 0.2717 -0.2717
KK/HlJ both 1.5833 0.1051 1.7908 1.3758
LP/J both 0.5 0.1123 0.7218 0.2782
NOD/ShiLtJ both 0.1667 0.1123 0.3885 -0.0551
NON/ShiLtJ both 0.0 0.1123 0.2218 -0.2218
NZB/BlNJ both 0.0 0.1123 0.2218 -0.2218
NZW/LacJ both 0.0 0.1123 0.2218 -0.2218
PERA/EiJ both 0.0 0.1256 0.248 -0.248
P/J both 1.0 0.1123 1.2218 0.7782
PL/J both 0.5 0.1123 0.7218 0.2782
RBF/DnJ both 0.0 0.1123 0.2218 -0.2218
RF/J both 1.1667 0.1123 1.3885 0.9449
RIIIS/J both 0.5 0.1123 0.7218 0.2782
SEA/GnJ both 0.0 0.1123 0.2218 -0.2218
SJL/J both 0.0 0.1123 0.2218 -0.2218
SM/J both 0.1667 0.1123 0.3885 -0.0551
SPRET/EiJ both 0.3333 0.1123 0.5551 0.1115
SWR/J both 0.0 0.1123 0.2218 -0.2218
WSB/EiJ both 0.0 0.1123 0.2218 -0.2218




  GWAS USING LINEAR MIXED MODELS