Phenotype measure

ID, description, units MPD:2922   nonHDL_Ch   plasma cholesterol not in the HDL fraction   [mg/dL]
high-fat diet study
Data set, strains Paigen1   inbred   43 strains     sex: both     age: 15-19wks
Procedure lipid profile
Ontology mappings


  STRAIN COMPARISON PLOT
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Paigen1 - plasma cholesterol not in the HDL fraction



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains42 strains
Mean of the strain means150   mg/dL 137   mg/dL
Median of the strain means127   mg/dL 118   mg/dL
SD of the strain means± 86.7 ± 104
Coefficient of variation (CV)0.580 0.756
Min–max range of strain means42.7   –   473   mg/dL 41.8   –   605   mg/dL
Mean sample size per strain8.2   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 838.467 838.467 0.2691 0.6041
strain 40 5280671.5758 132016.7894 42.3712 < 0.0001
sex:strain 40 665643.716 16641.0929 5.341 < 0.0001
Residuals 600 1869434.0661 3115.7234


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 143.0 19.4   9 6.47 0.136 114.0, 170.0 -0.08
129S1/SvImJ m 80.0 39.7   9 13.2 0.497 20.2, 128.0 -0.55
A/J f 245.0 117.0   9 39.0 0.478 129.0, 542.0 1.1
A/J m 190.0 23.4   10 7.4 0.123 160.0, 224.0 0.51
AKR/J f 64.9 24.3   8 8.59 0.375 36.7, 97.5 -0.98
AKR/J m 45.7 6.26   9 2.09 0.137 34.0, 52.0 -0.88
BALB/cJ f 69.7 16.9   10 5.34 0.242 42.0, 91.0 -0.92
BALB/cJ m 55.9 21.9   10 6.94 0.392 25.0, 93.0 -0.78
BPH/2J f 99.7 46.3   9 15.4 0.465 16.0, 166.0 -0.57
BPH/2J m 54.1 41.0   8 14.5 0.757 0.0, 105.0 -0.8
BPL/1J f 85.7 18.8   9 6.28 0.22 70.0, 116.0 -0.74
BPL/1J m 46.9 14.9   8 5.28 0.319 27.0, 67.0 -0.87
BPN/3J f 95.0 14.5   10 4.58 0.152 72.0, 116.0 -0.63
BPN/3J m 125.0 26.4   8 9.34 0.212 80.0, 168.0 -0.12
BTBR T+ Itpr3tf/J f 115.0 12.3   9 4.1 0.107 101.0, 139.0 -0.4
BTBR T+ Itpr3tf/J m 118.0 20.5   13 5.67 0.173 90.0, 154.0 -0.18
C3H/HeJ f 227.0 12.0   8 4.24 0.0529 207.0, 244.0 0.89
C3H/HeJ m 133.0 40.2   10 12.7 0.302 79.0, 213.0 -0.04
C57BL/10J f 74.9 14.3   10 4.52 0.191 52.0, 100.0 -0.86
C57BL/10J m 115.0 15.3   9 5.11 0.133 91.0, 138.0 -0.21
C57BL/6J f 124.0 20.5   13 5.69 0.165 80.0, 153.0 -0.29
C57BL/6J m 205.0 39.3   15 10.1 0.192 133.0, 280.0 0.66
C57BLKS/J f 109.0 30.8   24 6.28 0.281 62.0, 169.0 -0.47
C57BLKS/J m 118.0 36.5   15 9.42 0.309 74.0, 191.0 -0.18
C57BR/cdJ f 209.0 46.2   7 17.5 0.221 149.0, 288.0 0.69
C57BR/cdJ m 152.0 25.7   9 8.56 0.169 113.0, 198.0 0.14
C57L/J f 87.7 9.38   7 3.54 0.107 76.0, 102.0 -0.71
C57L/J m 97.1 16.7   9 5.58 0.172 69.0, 125.0 -0.39
C58/J f 227.0 49.8   8 17.6 0.219 159.0, 305.0 0.89
C58/J m 440.0 168.0   10 53.2 0.383 163.0, 639.0 2.93
CAST/EiJ f 392.0 67.3   5 30.1 0.171 301.0, 453.0 2.8
CAST/EiJ m 235.0 42.3   9 14.1 0.18 180.0, 310.0 0.95
CBA/J f 54.0 6.28   9 2.09 0.116 45.0, 65.0 -1.1
CBA/J m 69.0 22.4   10 7.08 0.324 41.0, 106.0 -0.66
CE/J f 105.0 27.8   9 9.26 0.264 65.0, 144.0 -0.51
CE/J m 172.0 45.4   5 20.3 0.264 109.0, 231.0 0.34
CZECHII/EiJ f 163.0 31.3   6 12.8 0.192 117.0, 194.0 0.16
CZECHII/EiJ m 154.0 111.0   7 41.8 0.716 53.0, 342.0 0.16
DBA/1J f 75.8 14.4   5 6.42 0.189 56.0, 91.0 -0.85
DBA/1J m 91.2 42.9   6 17.5 0.47 50.0, 150.0 -0.44
DBA/2J f 66.9 13.2   9 4.39 0.197 41.0, 83.0 -0.95
DBA/2J m 50.2 13.6   5 6.1 0.272 38.0, 66.0 -0.84
FVB/NJ f 91.0 23.1   10 7.31 0.254 54.0, 129.0 -0.68
FVB/NJ m 117.0 58.8   3 33.9 0.501 67.1, 182.0 -0.19
I/LnJ f 135.0 21.9   9 7.31 0.163 99.0, 173.0 -0.17
I/LnJ m 124.0 21.1   9 7.02 0.169 81.0, 151.0 -0.13
KK/HlJ f 229.0 49.0   8 17.3 0.214 166.0, 314.0 0.92
KK/HlJ m 83.0 26.8   8 9.47 0.323 34.0, 116.0 -0.52
LP/J f 69.0 24.1   9 8.03 0.349 33.0, 104.0 -0.93
LP/J m 41.8 21.3   10 6.75 0.511 8.0, 68.0 -0.92
MOLF/EiJ f 473.0 44.7   7 16.9 0.0944 401.0, 521.0 3.73
MOLF/EiJ m 605.0 349.0   8 123.0 0.576 104.0, 1010.0 4.52
NOD/ShiLtJ f 211.0 83.0   9 27.7 0.393 147.0, 421.0 0.71
NOD/ShiLtJ m 170.0 22.6   7 8.55 0.133 134.0, 200.0 0.32
NON/ShiLtJ f 122.0 16.4   8 5.79 0.134 94.0, 142.0 -0.32
NON/ShiLtJ m 123.0 36.0   9 12.0 0.293 61.0, 178.0 -0.14
NZB/BlNJ f 206.0 38.6   9 12.9 0.188 147.0, 263.0 0.65
NZB/BlNJ m 166.0 21.2   9 7.06 0.128 135.0, 196.0 0.28
NZW/LacJ f 121.0 35.6   7 13.4 0.294 71.0, 178.0 -0.33
NZW/LacJ m 88.8 21.4   9 7.15 0.242 51.0, 126.0 -0.47
PERA/EiJ f 142.0 36.0   8 12.7 0.253 96.0, 192.0 -0.09
PERA/EiJ m 137.0 7.55   3 4.36 0.0551 130.0, 145.0 0.0
P/J f 190.0 29.2   6 11.9 0.154 164.0, 240.0 0.47
P/J m 114.0 18.2   9 6.06 0.159 88.0, 139.0 -0.22
PL/J f 133.0 37.6   7 14.2 0.282 83.0, 197.0 -0.19
PL/J m 128.0 28.7   3 16.6 0.224 95.0, 147.0 -0.09
RBF/DnJ f 268.0 47.9   8 16.9 0.179 206.0, 328.0 1.37
RBF/DnJ m 259.0 39.1   6 16.0 0.151 209.0, 322.0 1.18
RF/J f 61.7 8.7   9 2.9 0.141 52.0, 75.0 -1.01
RF/J m 56.3 34.8   6 14.2 0.618 0.0, 103.0 -0.78
RIIIS/J f 112.0 18.8   7 7.1 0.168 85.0, 137.0 -0.43
RIIIS/J m 74.1 25.5   7 9.63 0.344 40.0, 116.0 -0.61
SEA/GnJ f 127.0 16.3   8 5.75 0.128 109.0, 153.0 -0.26
SEA/GnJ m 74.4 20.4   9 6.82 0.275 41.0, 105.0 -0.6
SJL/J f 127.0 30.4   9 10.1 0.24 81.0, 182.0 -0.26
SJL/J m 89.0 0.0   1   0.0 0.0 89.0, 89.0 -0.46
SM/J f 173.0 48.9   8 17.3 0.282 83.0, 232.0 0.27
SM/J m 200.0 73.3   6 29.9 0.367 72.0, 268.0 0.61
SPRET/EiJ f 42.7 37.9   6 15.5 0.889 0.0, 107.0 -1.23
SPRET/EiJ m 59.2 54.0   5 24.2 0.913 0.0, 119.0 -0.75
SWR/J f 175.0 14.9   8 5.26 0.0848 159.0, 200.0 0.29
SWR/J m 148.0 36.1   5 16.1 0.244 113.0, 201.0 0.11
WSB/EiJ f 185.0 42.7   7 16.1 0.231 145.0, 274.0 0.41
WSB/EiJ m 149.0 24.4   6 9.97 0.164 127.0, 187.0 0.12
YBR/EiJ f 202.0 99.1   5 44.3 0.492 130.0, 373.0 0.61


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 142.5556 18.6062 179.0968 106.0143
129S1/SvImJ m 79.9778 18.6062 116.519 43.4365
A/J f 244.8889 18.6062 281.4301 208.3477
A/J m 190.0 17.6514 224.6661 155.3339
AKR/J f 64.8875 19.7349 103.6453 26.1297
AKR/J m 45.6667 18.6062 82.2079 9.1254
BALB/cJ f 69.7 17.6514 104.3661 35.0339
BALB/cJ m 55.9 17.6514 90.5661 21.2339
BPH/2J f 99.6667 18.6062 136.2079 63.1254
BPH/2J m 54.125 19.7349 92.8828 15.3672
BPL/1J f 85.6667 18.6062 122.2079 49.1254
BPL/1J m 46.875 19.7349 85.6328 8.1172
BPN/3J f 95.0 17.6514 129.6661 60.3339
BPN/3J m 124.75 19.7349 163.5078 85.9922
BTBR T+ Itpr3tf/J f 115.2222 18.6062 151.7635 78.681
BTBR T+ Itpr3tf/J m 118.0769 15.4813 148.4811 87.6728
C3H/HeJ f 227.125 19.7349 265.8828 188.3672
C3H/HeJ m 132.9 17.6514 167.5661 98.2339
C57BL/10J f 74.9 17.6514 109.5661 40.2339
C57BL/10J m 115.2222 18.6062 151.7635 78.681
C57BL/6J f 124.3846 15.4813 154.7888 93.9805
C57BL/6J m 204.6 14.4123 232.9047 176.2953
C57BLKS/J f 109.3333 11.3939 131.7102 86.9565
C57BLKS/J m 118.2 14.4123 146.5047 89.8953
C57BR/cdJ f 209.1429 21.0975 250.5767 167.709
C57BR/cdJ m 151.6667 18.6062 188.2079 115.1254
C57L/J f 87.7143 21.0975 129.1482 46.2804
C57L/J m 97.1111 18.6062 133.6523 60.5699
C58/J f 227.25 19.7349 266.0078 188.4922
C58/J m 439.8 17.6514 474.4661 405.1339
CAST/EiJ f 392.2 24.9629 441.2252 343.1748
CAST/EiJ m 235.2222 18.6062 271.7635 198.681
CBA/J f 54.0 18.6062 90.5412 17.4588
CBA/J m 69.0 17.6514 103.6661 34.3339
CE/J f 105.2222 18.6062 141.7635 68.681
CE/J m 172.0 24.9629 221.0252 122.9748
CZECHII/EiJ f 162.8333 22.7879 207.587 118.0796
CZECHII/EiJ m 154.4286 21.0975 195.8624 112.9947
DBA/1J f 75.8 24.9629 124.8252 26.7748
DBA/1J m 91.1667 22.7879 135.9204 46.413
DBA/2J f 66.8889 18.6062 103.4301 30.3477
DBA/2J m 50.2 24.9629 99.2252 1.1748
FVB/NJ f 91.02 17.6514 125.6861 56.3539
FVB/NJ m 117.3667 32.2269 180.6579 54.0754
I/LnJ f 134.7778 18.6062 171.319 98.2365
I/LnJ m 124.4444 18.6062 160.9857 87.9032
KK/HlJ f 228.75 19.7349 267.5078 189.9922
KK/HlJ m 83.0 19.7349 121.7578 44.2422
LP/J f 69.0 18.6062 105.5412 32.4588
LP/J m 41.8 17.6514 76.4661 7.1339
MOLF/EiJ f 472.8571 21.0975 514.291 431.4233
MOLF/EiJ m 605.0 19.7349 643.7578 566.2422
NOD/ShiLtJ f 211.2222 18.6062 247.7635 174.681
NOD/ShiLtJ m 169.7143 21.0975 211.1482 128.2804
NON/ShiLtJ f 122.125 19.7349 160.8828 83.3672
NON/ShiLtJ m 123.1111 18.6062 159.6523 86.5699
NZB/BlNJ f 206.1111 18.6062 242.6523 169.5699
NZB/BlNJ m 166.0 18.6062 202.5412 129.4588
NZW/LacJ f 121.0 21.0975 162.4339 79.5661
NZW/LacJ m 88.7778 18.6062 125.319 52.2365
PERA/EiJ f 142.25 19.7349 181.0078 103.4922
PERA/EiJ m 137.0 32.2269 200.2913 73.7087
P/J f 189.5 22.7879 234.2537 144.7463
P/J m 114.1111 18.6062 150.6523 77.5699
PL/J f 133.1429 21.0975 174.5767 91.709
PL/J m 128.0 32.2269 191.2913 64.7087
RBF/DnJ f 267.5 19.7349 306.2578 228.7422
RBF/DnJ m 259.3333 22.7879 304.087 214.5796
RF/J f 61.6667 18.6062 98.2079 25.1254
RF/J m 56.3333 22.7879 101.087 11.5796
RIIIS/J f 111.7143 21.0975 153.1482 70.2804
RIIIS/J m 74.1429 21.0975 115.5767 32.709
SEA/GnJ f 126.75 19.7349 165.5078 87.9922
SEA/GnJ m 74.4444 18.6062 110.9857 37.9032
SM/J f 173.0 19.7349 211.7578 134.2422
SM/J m 199.6667 22.7879 244.4204 154.913
SPRET/EiJ f 42.6667 22.7879 87.4204 0.0
SPRET/EiJ m 59.2 24.9629 108.2252 10.1748
SWR/J f 175.375 19.7349 214.1328 136.6172
SWR/J m 147.6 24.9629 196.6252 98.5748
WSB/EiJ f 185.0 21.0975 226.4339 143.5661
WSB/EiJ m 148.8333 22.7879 193.587 104.0796


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 111.2667 13.1566 137.1052 85.4281
A/J both 217.4444 12.8235 242.6288 192.2601
AKR/J both 55.2771 13.5615 81.9109 28.6433
BALB/cJ both 62.8 12.4814 87.3126 38.2874
BPH/2J both 76.8958 13.5615 103.5296 50.2621
BPL/1J both 66.2708 13.5615 92.9046 39.6371
BPN/3J both 109.875 13.2386 135.8745 83.8755
BTBR T+ Itpr3tf/J both 116.6496 12.1023 140.4176 92.8816
C3H/HeJ both 180.0125 13.2386 206.012 154.013
C57BL/10J both 95.0611 12.8235 120.2454 69.8768
C57BL/6J both 164.4923 10.5757 185.2623 143.7223
C57BLKS/J both 113.7667 9.1861 131.8075 95.7259
C57BR/cdJ both 180.4048 14.065 208.0273 152.7822
C57L/J both 92.4127 14.065 120.0353 64.7901
C58/J both 333.525 13.2386 359.5245 307.5255
CAST/EiJ both 313.7111 15.5671 344.2837 283.1385
CBA/J both 61.5 12.8235 86.6843 36.3157
CE/J both 138.6111 15.5671 169.1837 108.0385
CZECHII/EiJ both 158.631 15.5273 189.1255 128.1365
DBA/1J both 83.4833 16.8999 116.6736 50.2931
DBA/2J both 58.5444 15.5671 89.117 27.9719
FVB/NJ both 104.1933 18.3722 140.2749 68.1118
I/LnJ both 129.6111 13.1566 155.4497 103.7726
KK/HlJ both 155.875 13.9547 183.2809 128.4691
LP/J both 55.4 12.8235 80.5843 30.2157
MOLF/EiJ both 538.9286 14.4445 567.2964 510.5607
NOD/ShiLtJ both 190.4683 14.065 218.0908 162.8457
NON/ShiLtJ both 122.6181 13.5615 149.2518 95.9843
NZB/BlNJ both 186.0556 13.1566 211.8941 160.217
NZW/LacJ both 104.8889 14.065 132.5115 77.2663
PERA/EiJ both 139.625 18.8947 176.7328 102.5172
P/J both 151.8056 14.7095 180.6939 122.9172
PL/J both 130.5714 19.2593 168.3952 92.7477
RBF/DnJ both 263.4167 15.0728 293.0185 233.8149
RF/J both 59.0 14.7095 87.8884 30.1116
RIIIS/J both 92.9286 14.9182 122.2267 63.6304
SEA/GnJ both 100.5972 13.5615 127.231 73.9634
SM/J both 186.3333 15.0728 215.9351 156.7315
SPRET/EiJ both 50.9333 16.8999 84.1236 17.7431
SWR/J both 161.4875 15.9108 192.7351 130.2399
WSB/EiJ both 166.9167 15.5273 197.4112 136.4222