Phenotype measure:   Paigen1   gbvol

ID, description, units MPD:2908   gbvol   gallbladder volume   [µL]
high-fat diet study
Data set, strains Paigen1   inbred   43 strains     sex: both     age: 15-19wks
Procedure organ dimensions
Ontology mappings

  STRAIN COMPARISON PLOT
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Paigen1 - gallbladder volume



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains42 strains
Mean of the strain means15.5   µL 17.3   µL
Median of the strain means10.7   µL 11.6   µL
SD of the strain means± 13.0 ± 14.6
Coefficient of variation (CV)0.839 0.843
Min–max range of strain means0.800   –   59.1   µL 1.58   –   65.7   µL
Mean sample size per strain8.4   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 636.01 636.01 5.1073 0.0242
strain 41 109758.5802 2677.0385 21.4971 < 0.0001
sex:strain 41 13801.9911 336.6339 2.7032 < 0.0001
Residuals 614 76461.4551 124.5301


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 29.3 11.9   10 3.78 0.407 9.7, 52.2 1.06
129S1/SvImJ m 33.2 15.6   10 4.93 0.47 16.0, 61.7 1.09
A/J f 33.5 14.4   9 4.81 0.431 14.1, 67.6 1.38
A/J m 25.9 12.3   10 3.9 0.476 13.8, 56.5 0.59
AKR/J f 11.0 5.29   8 1.87 0.479 2.8, 20.1 -0.35
AKR/J m 5.68 3.63   5 1.62 0.639 1.2, 10.3 -0.8
BALB/cJ f 7.22 4.17   9 1.39 0.578 4.2, 17.2 -0.64
BALB/cJ m 7.91 4.31   10 1.36 0.545 2.7, 15.4 -0.64
BPH/2J f 7.07 3.57   9 1.19 0.505 0.6, 13.7 -0.65
BPH/2J m 8.7 4.55   9 1.52 0.523 3.3, 17.6 -0.59
BPL/1J f 8.04 3.87   9 1.29 0.48 3.3, 13.9 -0.57
BPL/1J m 10.0 3.67   9 1.22 0.366 3.1, 15.1 -0.5
BPN/3J f 18.3 8.83   8 3.12 0.481 4.3, 30.1 0.22
BPN/3J m 27.2 10.3   9 3.42 0.377 15.3, 44.3 0.68
BTBR T+ Itpr3tf/J f 13.0 5.52   9 1.84 0.424 4.2, 22.2 -0.19
BTBR T+ Itpr3tf/J m 18.4 12.7   16 3.18 0.691 1.5, 40.0 0.08
C3H/HeJ f 7.37 3.03   9 1.01 0.412 3.4, 12.6 -0.62
C3H/HeJ m 11.0 6.77   10 2.14 0.614 3.3, 25.0 -0.43
C57BL/10J f 15.9 5.97   10 1.89 0.376 5.3, 24.5 0.03
C57BL/10J m 13.0 11.1   9 3.72 0.858 4.3, 34.3 -0.29
C57BL/6J f 23.6 7.96   20 1.78 0.338 13.0, 40.6 0.62
C57BL/6J m 28.7 11.0   16 2.75 0.383 10.1, 45.5 0.79
C57BLKS/J f 7.45 2.35   15 0.606 0.315 2.8, 11.4 -0.62
C57BLKS/J m 10.1 4.4   12 1.27 0.435 0.3, 14.5 -0.49
C57BR/cdJ f 12.5 5.23   9 1.74 0.42 4.8, 19.9 -0.23
C57BR/cdJ m 8.83 5.71   10 1.8 0.646 4.4, 22.9 -0.58
C57L/J f 12.8 12.4   9 4.13 0.971 3.2, 33.5 -0.21
C57L/J m 12.8 6.71   9 2.24 0.526 5.5, 26.3 -0.31
C58/J f 28.9 9.4   10 2.97 0.326 11.4, 39.4 1.03
C58/J m 65.7 40.0   10 12.6 0.608 23.9, 152.0 3.33
CAST/EiJ f 7.6 3.72   4 1.86 0.49 3.6, 11.2 -0.61
CAST/EiJ m 7.74 5.36   9 1.79 0.692 0.8, 16.0 -0.66
CBA/J f 10.7 6.08   6 2.48 0.566 5.3, 22.0 -0.37
CBA/J m 5.85 5.77   6 2.36 0.987 1.7, 17.4 -0.78
CE/J f 0.8 0.327   7 0.123 0.408 0.5, 1.3 -1.13
CE/J m 17.9 31.0   5 13.9 1.73 0.9, 72.6 0.04
CZECHII/EiJ f 9.12 4.72   6 1.93 0.518 4.0, 14.9 -0.49
CZECHII/EiJ m 6.49 3.46   7 1.31 0.534 3.0, 13.1 -0.74
DBA/1J f 6.16 2.34   10 0.741 0.381 1.4, 9.6 -0.72
DBA/1J m 6.07 3.26   6 1.33 0.538 2.1, 11.5 -0.77
DBA/2J f 5.07 3.57   9 1.19 0.704 1.3, 13.5 -0.8
DBA/2J m 5.94 8.84   9 2.95 1.49 0.4, 27.8 -0.78
FVB/NJ f 17.0 3.22   8 1.14 0.19 14.4, 23.7 0.12
FVB/NJ m 23.6 3.11   3 1.8 0.132 20.2, 26.3 0.43
I/LnJ f 23.2 7.37   7 2.79 0.317 14.8, 36.6 0.59
I/LnJ m 19.7 5.65   9 1.88 0.287 12.2, 31.7 0.17
KK/HlJ f 8.35 8.52   6 3.48 1.02 1.1, 24.4 -0.55
KK/HlJ m 29.5 25.2   8 8.93 0.857 8.3, 82.4 0.84
LP/J f 23.4 10.0   7 3.79 0.428 11.7, 40.5 0.61
LP/J m 18.6 7.83   8 2.77 0.42 12.2, 35.9 0.09
MOLF/EiJ f 8.91 3.88   9 1.29 0.435 3.3, 14.8 -0.51
MOLF/EiJ m 26.9 11.4   9 3.8 0.425 11.0, 38.7 0.66
NOD/ShiLtJ f 59.1 27.2   8 9.61 0.46 10.7, 100.0 3.35
NOD/ShiLtJ m 40.6 29.7   5 13.3 0.732 15.2, 85.0 1.6
NON/ShiLtJ f 34.9 4.26   9 1.42 0.122 26.9, 42.9 1.49
NON/ShiLtJ m 29.5 8.81   9 2.94 0.299 12.2, 43.5 0.84
NZB/BlNJ f 13.7 6.58   9 2.19 0.479 3.9, 26.8 -0.14
NZB/BlNJ m 5.52 3.17   8 1.12 0.574 2.1, 10.4 -0.81
NZW/LacJ f 15.6 2.38   8 0.842 0.152 11.4, 18.6 0.01
NZW/LacJ m 16.6 8.05   8 2.85 0.484 3.7, 27.4 -0.05
PERA/EiJ f 51.9 21.3   8 7.55 0.411 19.9, 76.2 2.8
PERA/EiJ m 61.1 49.1   4 24.6 0.803 17.1, 123.0 3.01
P/J f 10.5 5.98   9 1.99 0.569 4.6, 22.3 -0.38
P/J m 14.7 10.3   7 3.9 0.703 1.1, 28.0 -0.18
PL/J f 3.21 1.9   10 0.599 0.59 0.9, 5.7 -0.94
PL/J m 5.13 1.17   3 0.677 0.228 3.8, 6.0 -0.83
RBF/DnJ f 13.7 7.0   8 2.47 0.511 1.6, 22.9 -0.14
RBF/DnJ m 12.2 12.2   8 4.33 1.0 3.0, 32.0 -0.35
RF/J f 7.61 2.42   9 0.807 0.318 4.5, 10.7 -0.61
RF/J m 6.86 3.83   5 1.71 0.558 1.1, 11.3 -0.72
RIIIS/J f 45.4 15.7   9 5.22 0.345 18.0, 61.4 2.3
RIIIS/J m 40.2 20.6   9 6.86 0.511 18.3, 79.7 1.58
SEA/GnJ f 9.17 3.52   6 1.44 0.384 5.9, 15.6 -0.49
SEA/GnJ m 9.11 4.35   9 1.45 0.478 4.6, 17.9 -0.56
SJL/J f 6.64 3.12   8 1.1 0.47 0.8, 9.5 -0.68
SJL/J m 4.76 2.16   7 0.818 0.455 1.2, 7.6 -0.86
SM/J f 9.69 3.17   7 1.2 0.328 3.3, 12.6 -0.45
SM/J m 4.2 2.23   3 1.29 0.532 1.7, 6.0 -0.9
SPRET/EiJ f 7.91 3.77   7 1.42 0.476 4.0, 13.7 -0.58
SPRET/EiJ m 10.3 3.51   4 1.75 0.341 7.0, 13.6 -0.48
SWR/J f 11.7 3.49   10 1.1 0.298 5.7, 16.6 -0.29
SWR/J m 7.67 2.99   7 1.13 0.39 4.3, 12.0 -0.66
WSB/EiJ f 2.31 2.05   7 0.774 0.885 0.5, 6.8 -1.01
WSB/EiJ m 1.58 0.694   5 0.31 0.439 1.1, 2.8 -1.08
YBR/EiJ f 7.05 0.0707   2   0.05 0.01 7.0, 7.1 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 29.33 3.5289 36.2601 22.3999
129S1/SvImJ m 33.19 3.5289 40.1201 26.2599
A/J f 33.4667 3.7198 40.7717 26.1617
A/J m 25.87 3.5289 32.8001 18.9399
AKR/J f 11.0375 3.9454 18.7856 3.2894
AKR/J m 5.68 4.9906 15.4807 0.0
BALB/cJ f 7.2222 3.7198 14.5272 0.0
BALB/cJ m 7.91 3.5289 14.8401 0.9799
BPH/2J f 7.0667 3.7198 14.3717 0.0
BPH/2J m 8.7 3.7198 16.005 1.395
BPL/1J f 8.0444 3.7198 15.3495 0.7394
BPL/1J m 10.0333 3.7198 17.3383 2.7283
BPN/3J f 18.3375 3.9454 26.0856 10.5894
BPN/3J m 27.2333 3.7198 34.5383 19.9283
BTBR T+ Itpr3tf/J f 13.0222 3.7198 20.3272 5.7172
BTBR T+ Itpr3tf/J m 18.4125 2.7898 23.8913 12.9337
C3H/HeJ f 7.3667 3.7198 14.6717 0.0617
C3H/HeJ m 11.02 3.5289 17.9501 4.0899
C57BL/10J f 15.87 3.5289 22.8001 8.9399
C57BL/10J m 12.9889 3.7198 20.2939 5.6839
C57BL/6J f 23.595 2.4953 28.4954 18.6946
C57BL/6J m 28.7063 2.7898 34.185 23.2275
C57BLKS/J f 7.4533 2.8813 13.1118 1.7949
C57BLKS/J m 10.1083 3.2214 16.4347 3.782
C57BR/cdJ f 12.4556 3.7198 19.7606 5.1505
C57BR/cdJ m 8.83 3.5289 15.7601 1.8999
C57L/J f 12.7556 3.7198 20.0606 5.4505
C57L/J m 12.7556 3.7198 20.0606 5.4505
C58/J f 28.85 3.5289 35.7801 21.9199
C58/J m 65.69 3.5289 72.6201 58.7599
CAST/EiJ f 7.6 5.5797 18.5575 0.0
CAST/EiJ m 7.7444 3.7198 15.0495 0.4394
CBA/J f 10.7333 4.5558 19.6801 1.7866
CBA/J m 5.85 4.5558 14.7968 0.0
CE/J f 0.8 4.2178 9.0831 0.0
CE/J m 17.86 4.9906 27.6607 8.0593
CZECHII/EiJ f 9.1167 4.5558 18.0634 0.1699
CZECHII/EiJ m 6.4857 4.2178 14.7688 0.0
DBA/1J f 6.16 3.5289 13.0901 0.0
DBA/1J m 6.0667 4.5558 15.0134 0.0
DBA/2J f 5.0667 3.7198 12.3717 0.0
DBA/2J m 5.9444 3.7198 13.2495 0.0
FVB/NJ f 16.975 3.9454 24.7231 9.2269
FVB/NJ m 23.6 6.4428 36.2526 10.9474
I/LnJ f 23.2429 4.2178 31.526 14.9598
I/LnJ m 19.7111 3.7198 27.0161 12.4061
KK/HlJ f 8.35 4.5558 17.2968 0.0
KK/HlJ m 29.45 3.9454 37.1981 21.7019
LP/J f 23.4 4.2178 31.6831 15.1169
LP/J m 18.625 3.9454 26.3731 10.8769
MOLF/EiJ f 8.9111 3.7198 16.2161 1.6061
MOLF/EiJ m 26.8667 3.7198 34.1717 19.5617
NOD/ShiLtJ f 59.15 3.9454 66.8981 51.4019
NOD/ShiLtJ m 40.56 4.9906 50.3607 30.7593
NON/ShiLtJ f 34.8778 3.7198 42.1828 27.5728
NON/ShiLtJ m 29.5 3.7198 36.805 22.195
NZB/BlNJ f 13.7444 3.7198 21.0495 6.4394
NZB/BlNJ m 5.525 3.9454 13.2731 0.0
NZW/LacJ f 15.65 3.9454 23.3981 7.9019
NZW/LacJ m 16.6375 3.9454 24.3856 8.8894
PERA/EiJ f 51.95 3.9454 59.6981 44.2019
PERA/EiJ m 61.15 5.5797 72.1075 50.1925
P/J f 10.5111 3.7198 17.8161 3.2061
P/J m 14.7 4.2178 22.9831 6.4169
PL/J f 3.21 3.5289 10.1401 0.0
PL/J m 5.1333 6.4428 17.786 0.0
RBF/DnJ f 13.6875 3.9454 21.4356 5.9394
RBF/DnJ m 12.2375 3.9454 19.9856 4.4894
RF/J f 7.6111 3.7198 14.9161 0.3061
RF/J m 6.86 4.9906 16.6607 0.0
RIIIS/J f 45.3778 3.7198 52.6828 38.0728
RIIIS/J m 40.2444 3.7198 47.5495 32.9394
SEA/GnJ f 9.1667 4.5558 18.1134 0.2199
SEA/GnJ m 9.1111 3.7198 16.4161 1.8061
SJL/J f 6.6375 3.9454 14.3856 0.0
SJL/J m 4.7571 4.2178 13.0402 0.0
SM/J f 9.6857 4.2178 17.9688 1.4026
SM/J m 4.2 6.4428 16.8526 0.0
SPRET/EiJ f 7.9143 4.2178 16.1974 0.0
SPRET/EiJ m 10.275 5.5797 21.2325 0.0
SWR/J f 11.71 3.5289 18.6401 4.7799
SWR/J m 7.6714 4.2178 15.9545 0.0
WSB/EiJ f 2.3143 4.2178 10.5974 0.0
WSB/EiJ m 1.58 4.9906 11.3807 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 31.26 2.4953 36.1604 26.3596
A/J both 29.6683 2.5637 34.703 24.6337
AKR/J both 8.3588 3.1809 14.6055 2.112
BALB/cJ both 7.5661 2.5637 12.6007 2.5315
BPH/2J both 7.8833 2.6303 13.0488 2.7179
BPL/1J both 9.0389 2.6303 14.2043 3.8735
BPN/3J both 22.7854 2.7112 28.1098 17.461
BTBR T+ Itpr3tf/J both 15.7174 2.3249 20.283 11.1517
C3H/HeJ both 9.1933 2.5637 14.228 4.1587
C57BL/10J both 14.4294 2.5637 19.4641 9.3948
C57BL/6J both 26.1506 1.8715 29.8259 22.4754
C57BLKS/J both 8.7808 2.161 13.0247 4.537
C57BR/cdJ both 10.6428 2.5637 15.6774 5.6081
C57L/J both 12.7556 2.6303 17.921 7.5901
C58/J both 47.27 2.4953 52.1704 42.3696
CAST/EiJ both 7.6722 3.353 14.2569 1.0876
CBA/J both 8.2917 3.2214 14.618 1.9653
CE/J both 9.33 3.2671 15.7461 2.9139
CZECHII/EiJ both 7.8012 3.1042 13.8974 1.705
DBA/1J both 6.1133 2.8813 11.7718 0.4549
DBA/2J both 5.5056 2.6303 10.671 0.3401
FVB/NJ both 20.2875 3.7774 27.7058 12.8692
I/LnJ both 21.477 2.8119 26.9991 15.9549
KK/HlJ both 18.9 3.0134 24.8177 12.9823
LP/J both 21.0125 2.8877 26.6836 15.3414
MOLF/EiJ both 17.8889 2.6303 23.0543 12.7235
NOD/ShiLtJ both 49.855 3.1809 56.1017 43.6083
NON/ShiLtJ both 32.1889 2.6303 37.3543 27.0235
NZB/BlNJ both 9.6347 2.7112 14.9591 4.3103
NZW/LacJ both 16.1438 2.7898 21.6225 10.665
PERA/EiJ both 56.55 3.4168 63.2601 49.8399
P/J both 12.6056 2.8119 18.1276 7.0835
PL/J both 4.1717 3.673 11.3848 0.0
RBF/DnJ both 12.9625 2.7898 18.4413 7.4837
RF/J both 7.2356 3.1122 13.3474 1.1237
RIIIS/J both 42.8111 2.6303 47.9765 37.6457
SEA/GnJ both 9.1389 2.9407 14.914 3.3638
SJL/J both 5.6973 2.8877 11.3684 0.0263
SM/J both 6.9429 3.8503 14.5043 0.0
SPRET/EiJ both 9.0946 3.4972 15.9626 2.2267
SWR/J both 9.6907 2.7497 15.0906 4.2908
WSB/EiJ both 1.9471 3.2671 8.3632 0.0




  GWAS USING LINEAR MIXED MODELS