Phenotype measure:   Paigen1   liverweight

ID, description, units MPD:2907   liverweight   liver weight at sacrifice   [g]
high-fat diet study
Data set, strains Paigen1   inbred   43 strains     sex: both     age: 15-19wks
Procedure organ weights
Ontology mappings

  STRAIN COMPARISON PLOT
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Paigen1 - liver weight at sacrifice



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains42 strains
Mean of the strain means1.75   g 1.90   g
Median of the strain means1.68   g 1.85   g
SD of the strain means± 0.529 ± 0.514
Coefficient of variation (CV)0.302 0.270
Min–max range of strain means0.754   –   2.76   g 0.824   –   3.30   g
Mean sample size per strain9.6   mice 8.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5.6898 5.6898 82.8451 < 0.0001
strain 41 176.3274 4.3007 62.6185 < 0.0001
sex:strain 41 16.44 0.401 5.8383 < 0.0001
Residuals 714 49.0378 0.0687


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.31 0.183   10 0.0578 0.139 1.03, 1.59 -0.84
129S1/SvImJ m 1.59 0.0977   10 0.0309 0.0614 1.45, 1.76 -0.61
A/J f 2.4 0.341   10 0.108 0.142 1.64, 2.95 1.22
A/J m 2.21 0.186   10 0.0589 0.0844 1.95, 2.54 0.59
AKR/J f 2.42 0.21   9 0.0699 0.0865 2.12, 2.69 1.26
AKR/J m 2.53 0.239   10 0.0755 0.0945 2.05, 2.88 1.22
BALB/cJ f 1.95 0.119   10 0.0378 0.0612 1.76, 2.11 0.37
BALB/cJ m 2.23 0.255   10 0.0806 0.114 1.82, 2.54 0.63
BPH/2J f 1.33 0.143   10 0.0451 0.107 1.1, 1.58 -0.8
BPH/2J m 1.29 0.16   9 0.0532 0.124 1.03, 1.57 -1.2
BPL/1J f 1.3 0.0545   10 0.0172 0.0419 1.19, 1.35 -0.86
BPL/1J m 1.66 0.155   10 0.0489 0.0928 1.38, 1.92 -0.48
BPN/3J f 1.45 0.163   10 0.0514 0.112 1.21, 1.82 -0.58
BPN/3J m 1.59 0.125   9 0.0417 0.0788 1.44, 1.77 -0.61
BTBR T+ Itpr3tf/J f 2.38 0.208   9 0.0692 0.0873 2.09, 2.79 1.18
BTBR T+ Itpr3tf/J m 2.26 0.224   16 0.056 0.0993 1.89, 2.96 0.69
C3H/HeJ f 1.65 0.286   10 0.0904 0.174 1.13, 2.23 -0.2
C3H/HeJ m 1.85 0.402   9 0.134 0.217 1.43, 2.5 -0.11
C57BL/10J f 1.33 0.0701   10 0.0222 0.0529 1.22, 1.43 -0.8
C57BL/10J m 1.73 0.116   10 0.0366 0.0669 1.54, 1.95 -0.34
C57BL/6J f 1.54 0.157   19 0.036 0.102 1.29, 1.89 -0.41
C57BL/6J m 1.76 0.291   16 0.0728 0.165 1.32, 2.18 -0.28
C57BLKS/J f 1.49 0.295   27 0.0569 0.199 1.05, 2.11 -0.5
C57BLKS/J m 1.7 0.476   16 0.119 0.279 1.28, 3.03 -0.4
C57BR/cdJ f 1.43 0.115   10 0.0364 0.0805 1.22, 1.62 -0.61
C57BR/cdJ m 1.77 0.204   10 0.0644 0.115 1.42, 2.1 -0.26
C57L/J f 1.69 0.255   10 0.0807 0.151 1.24, 2.27 -0.12
C57L/J m 1.63 0.131   10 0.0414 0.0803 1.51, 1.9 -0.53
C58/J f 2.51 0.217   10 0.0687 0.0864 2.22, 2.77 1.43
C58/J m 3.3 0.396   9 0.132 0.12 2.44, 3.89 2.71
CAST/EiJ f 0.878 0.153   8 0.054 0.174 0.73, 1.14 -1.66
CAST/EiJ m 1.02 0.06   9 0.02 0.0591 0.94, 1.11 -1.72
CBA/J f 1.51 0.144   10 0.0454 0.0952 1.25, 1.69 -0.46
CBA/J m 2.03 0.192   10 0.0606 0.0947 1.63, 2.26 0.24
CE/J f 2.43 0.306   10 0.0969 0.126 2.11, 3.01 1.28
CE/J m 2.15 0.427   7 0.162 0.199 1.57, 2.95 0.48
CZECHII/EiJ f 0.797 0.0799   7 0.0302 0.1 0.63, 0.89 -1.81
CZECHII/EiJ m 0.824 0.0777   5 0.0347 0.0942 0.73, 0.92 -2.1
DBA/1J f 1.47 0.125   10 0.0396 0.0853 1.3, 1.7 -0.54
DBA/1J m 1.27 0.0371   9 0.0124 0.0293 1.21, 1.33 -1.23
DBA/2J f 1.68 0.201   10 0.0636 0.12 1.32, 1.97 -0.14
DBA/2J m 2.03 0.184   9 0.0615 0.091 1.67, 2.36 0.24
FVB/NJ f 2.2 0.127   10 0.0401 0.0575 2.01, 2.39 0.84
FVB/NJ m 1.96 0.223   3 0.129 0.114 1.78, 2.21 0.11
I/LnJ f 1.83 0.189   10 0.0599 0.103 1.54, 2.14 0.14
I/LnJ m 1.63 0.278   10 0.0879 0.171 1.34, 2.24 -0.53
KK/HlJ f 2.76 0.376   9 0.125 0.136 2.37, 3.6 1.9
KK/HlJ m 2.53 0.749   9 0.25 0.296 1.21, 4.01 1.22
LP/J f 1.21 0.165   10 0.0521 0.136 0.96, 1.52 -1.03
LP/J m 1.7 0.242   10 0.0766 0.143 1.42, 2.24 -0.4
MOLF/EiJ f 1.53 0.22   9 0.0734 0.144 1.22, 1.87 -0.42
MOLF/EiJ m 2.21 0.237   10 0.0749 0.107 1.83, 2.56 0.59
NOD/ShiLtJ f 2.36 0.3   10 0.095 0.127 1.81, 2.82 1.14
NOD/ShiLtJ m 2.66 0.338   7 0.128 0.127 2.23, 3.2 1.47
NON/ShiLtJ f 2.61 0.194   10 0.0612 0.0741 2.34, 3.04 1.62
NON/ShiLtJ m 2.59 0.218   10 0.0688 0.0842 2.32, 3.03 1.33
NZB/BlNJ f 2.0 0.261   10 0.0826 0.13 1.66, 2.52 0.46
NZB/BlNJ m 2.85 0.242   9 0.0806 0.0848 2.46, 3.19 1.84
NZW/LacJ f 2.16 0.47   8 0.166 0.217 1.69, 2.93 0.77
NZW/LacJ m 2.24 0.324   10 0.102 0.145 1.78, 2.72 0.65
PERA/EiJ f 1.73 0.333   8 0.118 0.192 1.32, 2.17 -0.05
PERA/EiJ m 1.86 0.34   4 0.17 0.183 1.49, 2.23 -0.09
P/J f 1.5 0.155   10 0.049 0.103 1.31, 1.72 -0.48
P/J m 1.99 0.204   10 0.0644 0.102 1.67, 2.2 0.17
PL/J f 1.59 0.161   10 0.0508 0.101 1.42, 1.89 -0.31
PL/J m 1.79 0.0971   3 0.0561 0.0542 1.71, 1.9 -0.22
RBF/DnJ f 2.52 0.302   10 0.0955 0.12 2.06, 3.02 1.45
RBF/DnJ m 2.2 0.265   9 0.0882 0.12 1.7, 2.58 0.58
RF/J f 2.19 0.107   10 0.0339 0.049 2.04, 2.4 0.82
RF/J m 2.27 0.258   6 0.105 0.114 1.99, 2.73 0.71
RIIIS/J f 1.85 0.594   9 0.198 0.321 1.3, 3.24 0.18
RIIIS/J m 2.0 0.331   9 0.11 0.166 1.38, 2.48 0.19
SEA/GnJ f 1.78 0.127   9 0.0423 0.0712 1.53, 1.94 0.05
SEA/GnJ m 1.62 0.0835   10 0.0264 0.0515 1.45, 1.74 -0.55
SJL/J f 1.62 0.305   10 0.0964 0.188 1.34, 2.4 -0.25
SJL/J m 1.78 0.139   9 0.0465 0.0782 1.6, 2.0 -0.24
SM/J f 1.21 0.0784   8 0.0277 0.0646 1.06, 1.3 -1.03
SM/J m 1.68 0.231   6 0.0942 0.138 1.39, 2.07 -0.44
SPRET/EiJ f 0.754 0.113   7 0.0428 0.15 0.59, 0.94 -1.89
SPRET/EiJ m 0.888 0.0638   5 0.0285 0.0718 0.82, 0.96 -1.98
SWR/J f 2.49 0.295   10 0.0934 0.118 1.97, 3.1 1.39
SWR/J m 2.09 0.69   8 0.244 0.33 1.28, 3.6 0.36
WSB/EiJ f 0.805 0.0745   6 0.0304 0.0925 0.69, 0.87 -1.79
WSB/EiJ m 1.02 0.103   6 0.0419 0.101 0.85, 1.17 -1.72
YBR/EiJ f 1.8 0.303   5 0.136 0.168 1.42, 2.14 0.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.314 0.0829 1.4767 1.1513
129S1/SvImJ m 1.591 0.0829 1.7537 1.4283
A/J f 2.395 0.0829 2.5577 2.2323
A/J m 2.209 0.0829 2.3717 2.0463
AKR/J f 2.4233 0.0874 2.5948 2.2518
AKR/J m 2.526 0.0829 2.6887 2.3633
BALB/cJ f 1.952 0.0829 2.1147 1.7893
BALB/cJ m 2.226 0.0829 2.3887 2.0633
BPH/2J f 1.335 0.0829 1.4977 1.1723
BPH/2J m 1.2889 0.0874 1.4604 1.1174
BPL/1J f 1.299 0.0829 1.4617 1.1363
BPL/1J m 1.665 0.0829 1.8277 1.5023
BPN/3J f 1.451 0.0829 1.6137 1.2883
BPN/3J m 1.5867 0.0874 1.7582 1.4152
BTBR T+ Itpr3tf/J f 2.3778 0.0874 2.5493 2.2063
BTBR T+ Itpr3tf/J m 2.2556 0.0655 2.3843 2.127
C3H/HeJ f 1.645 0.0829 1.8077 1.4823
C3H/HeJ m 1.8511 0.0874 2.0226 1.6796
C57BL/10J f 1.326 0.0829 1.4887 1.1633
C57BL/10J m 1.728 0.0829 1.8907 1.5653
C57BL/6J f 1.54 0.0601 1.658 1.422
C57BL/6J m 1.7619 0.0655 1.8905 1.6332
C57BLKS/J f 1.4867 0.0504 1.5857 1.3876
C57BLKS/J m 1.7031 0.0655 1.8318 1.5745
C57BR/cdJ f 1.43 0.0829 1.5927 1.2673
C57BR/cdJ m 1.766 0.0829 1.9287 1.6033
C57L/J f 1.689 0.0829 1.8517 1.5263
C57L/J m 1.629 0.0829 1.7917 1.4663
C58/J f 2.514 0.0829 2.6767 2.3513
C58/J m 3.2956 0.0874 3.4671 3.124
CAST/EiJ f 0.8775 0.0927 1.0594 0.6956
CAST/EiJ m 1.0156 0.0874 1.1871 0.844
CBA/J f 1.508 0.0829 1.6707 1.3453
CBA/J m 2.026 0.0829 2.1887 1.8633
CE/J f 2.433 0.0829 2.5957 2.2703
CE/J m 2.1486 0.0991 2.343 1.9541
CZECHII/EiJ f 0.7971 0.0991 0.9916 0.6027
CZECHII/EiJ m 0.824 0.1172 1.0541 0.5939
DBA/1J f 1.468 0.0829 1.6307 1.3053
DBA/1J m 1.2667 0.0874 1.4382 1.0952
DBA/2J f 1.675 0.0829 1.8377 1.5123
DBA/2J m 2.0267 0.0874 2.1982 1.8552
FVB/NJ f 2.204 0.0829 2.3667 2.0413
FVB/NJ m 1.96 0.1513 2.2571 1.6629
I/LnJ f 1.833 0.0829 1.9957 1.6703
I/LnJ m 1.629 0.0829 1.7917 1.4663
KK/HlJ f 2.76 0.0874 2.9315 2.5885
KK/HlJ m 2.5333 0.0874 2.7048 2.3618
LP/J f 1.21 0.0829 1.3727 1.0473
LP/J m 1.699 0.0829 1.8617 1.5363
MOLF/EiJ f 1.5344 0.0874 1.706 1.3629
MOLF/EiJ m 2.214 0.0829 2.3767 2.0513
NOD/ShiLtJ f 2.359 0.0829 2.5217 2.1963
NOD/ShiLtJ m 2.6614 0.0991 2.8559 2.467
NON/ShiLtJ f 2.614 0.0829 2.7767 2.4513
NON/ShiLtJ m 2.586 0.0829 2.7487 2.4233
NZB/BlNJ f 2.005 0.0829 2.1677 1.8423
NZB/BlNJ m 2.8511 0.0874 3.0226 2.6796
NZW/LacJ f 2.1612 0.0927 2.3432 1.9793
NZW/LacJ m 2.239 0.0829 2.4017 2.0763
PERA/EiJ f 1.73 0.0927 1.9119 1.5481
PERA/EiJ m 1.86 0.131 2.1173 1.6027
P/J f 1.502 0.0829 1.6647 1.3393
P/J m 1.994 0.0829 2.1567 1.8313
PL/J f 1.587 0.0829 1.7497 1.4243
PL/J m 1.7933 0.1513 2.0904 1.4963
RBF/DnJ f 2.515 0.0829 2.6777 2.3523
RBF/DnJ m 2.2033 0.0874 2.3748 2.0318
RF/J f 2.188 0.0829 2.3507 2.0253
RF/J m 2.265 0.107 2.4751 2.0549
RIIIS/J f 1.8478 0.0874 2.0193 1.6763
RIIIS/J m 1.9978 0.0874 2.1693 1.8263
SEA/GnJ f 1.7844 0.0874 1.956 1.6129
SEA/GnJ m 1.622 0.0829 1.7847 1.4593
SJL/J f 1.618 0.0829 1.7807 1.4553
SJL/J m 1.7822 0.0874 1.9537 1.6107
SM/J f 1.2137 0.0927 1.3957 1.0318
SM/J m 1.6767 0.107 1.8867 1.4666
SPRET/EiJ f 0.7543 0.0991 0.9488 0.5598
SPRET/EiJ m 0.888 0.1172 1.1181 0.6579
SWR/J f 2.494 0.0829 2.6567 2.3313
SWR/J m 2.09 0.0927 2.2719 1.9081
WSB/EiJ f 0.805 0.107 1.0151 0.5949
WSB/EiJ m 1.02 0.107 1.2301 0.8099


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.4525 0.0586 1.5675 1.3375
A/J both 2.302 0.0586 2.417 2.187
AKR/J both 2.4747 0.0602 2.5929 2.3565
BALB/cJ both 2.089 0.0586 2.204 1.974
BPH/2J both 1.3119 0.0602 1.4301 1.1937
BPL/1J both 1.482 0.0586 1.597 1.367
BPN/3J both 1.5188 0.0602 1.637 1.4006
BTBR T+ Itpr3tf/J both 2.3167 0.0546 2.4239 2.2095
C3H/HeJ both 1.7481 0.0602 1.8663 1.6299
C57BL/10J both 1.527 0.0586 1.642 1.412
C57BL/6J both 1.6509 0.0445 1.7382 1.5636
C57BLKS/J both 1.5949 0.0413 1.6761 1.5137
C57BR/cdJ both 1.598 0.0586 1.713 1.483
C57L/J both 1.659 0.0586 1.774 1.544
C58/J both 2.9048 0.0602 3.023 2.7866
CAST/EiJ both 0.9465 0.0637 1.0715 0.8215
CBA/J both 1.767 0.0586 1.882 1.652
CE/J both 2.2908 0.0646 2.4176 2.164
CZECHII/EiJ both 0.8106 0.0767 0.9612 0.6599
DBA/1J both 1.3673 0.0602 1.4855 1.2491
DBA/2J both 1.8508 0.0602 1.969 1.7326
FVB/NJ both 2.082 0.0863 2.2513 1.9127
I/LnJ both 1.731 0.0586 1.846 1.616
KK/HlJ both 2.6467 0.0618 2.7679 2.5254
LP/J both 1.4545 0.0586 1.5695 1.3395
MOLF/EiJ both 1.8742 0.0602 1.9924 1.756
NOD/ShiLtJ both 2.5102 0.0646 2.637 2.3834
NON/ShiLtJ both 2.6 0.0586 2.715 2.485
NZB/BlNJ both 2.4281 0.0602 2.5463 2.3099
NZW/LacJ both 2.2001 0.0622 2.3222 2.0781
PERA/EiJ both 1.795 0.0802 1.9525 1.6375
P/J both 1.748 0.0586 1.863 1.633
PL/J both 1.6902 0.0863 1.8595 1.5208
RBF/DnJ both 2.3592 0.0602 2.4774 2.241
RF/J both 2.2265 0.0677 2.3593 2.0937
RIIIS/J both 1.9228 0.0618 2.0441 1.8015
SEA/GnJ both 1.7032 0.0602 1.8214 1.585
SJL/J both 1.7001 0.0602 1.8183 1.5819
SM/J both 1.4452 0.0708 1.5841 1.3063
SPRET/EiJ both 0.8211 0.0767 0.9718 0.6705
SWR/J both 2.292 0.0622 2.414 2.17
WSB/EiJ both 0.9125 0.0757 1.061 0.764




  GWAS USING LINEAR MIXED MODELS