Project measure / variable:   Paigen3   initbw

ID, description, units MPD:2805   initbw   body weight   [g]  start  
high-fat diet study
Data set, strains Paigen3   obesity mutants   8 strains     sex: both     age: 7-11wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Paigen3 - body weight start



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means30.2   g 34.8   g
Median of the strain means26.7   g 35.1   g
SD of the strain means± 12.1 ± 9.37
Coefficient of variation (CV)0.402 0.269
Min–max range of strain means18.8   –   50.6   g 23.8   –   52.4   g
Mean sample size per strain23.7   mice 25.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1469.6427 1469.6427 93.0951 < 0.0001
strain 6 35461.1977 5910.1996 374.3838 < 0.0001
sex:strain 6 1493.7072 248.9512 15.7699 < 0.0001
Residuals 336 5304.2554 15.7865


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6(AU)-Tubtub/J f 30.5 6.6   25 1.32 0.216 21.6, 46.7 0.02
B6(AU)-Tubtub/J m 38.7 6.98   26 1.37 0.18 23.8, 47.5 0.41
B6.BKS(D)-Leprdb/J m 40.0 3.28   23 0.684 0.082 32.9, 44.0 0.55
B6.Cg-Ay/J f 26.7 2.92   25 0.583 0.109 21.6, 32.7 -0.29
B6.Cg-Ay/J m 32.8 2.7   34 0.463 0.0823 28.1, 38.0 -0.22
B6.Cg-Lepob/J f 50.6 2.87   22 0.611 0.0567 45.2, 56.1 1.68
B6.Cg-Lepob/J m 52.4 4.93   30 0.901 0.0941 40.5, 59.9 1.88
BKS.Cg-Dock7m +/+ Leprdb/J f 42.6 3.93   28 0.743 0.0922 34.1, 49.4 1.02
BKS.Cg-Dock7m +/+ Leprdb/J m 37.4 4.0   23 0.834 0.107 31.0, 43.0 0.27
BKSChpLt.HRS-Cpefat/J f 22.9 4.26   19 0.977 0.186 15.2, 31.7 -0.6
BKSChpLt.HRS-Cpefat/J m 27.6 4.76   22 1.02 0.173 16.1, 37.9 -0.77
C57BL/6J f 19.3 1.55   20 0.347 0.0804 17.2, 22.9 -0.9
C57BL/6J m 25.9 1.52   20 0.34 0.0586 23.7, 29.1 -0.95
C57BLKS/J f 18.8 1.1   27 0.212 0.0587 17.0, 22.1 -0.94
C57BLKS/J m 23.8 0.911   29 0.169 0.0383 21.9, 25.7 -1.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J f 30.524 0.7946 32.0871 28.9609
B6(AU)-Tubtub/J m 38.6885 0.7792 40.2212 37.1557
B6.Cg-Ay/J f 26.684 0.7946 28.2471 25.1209
B6.Cg-Ay/J m 32.7941 0.6814 34.1345 31.4538
B6.Cg-Lepob/J f 50.5955 0.8471 52.2617 48.9292
B6.Cg-Lepob/J m 52.4367 0.7254 53.8636 51.0098
BKS.Cg-Dock7m +/+ Leprdb/J f 42.6286 0.7509 44.1056 41.1516
BKS.Cg-Dock7m +/+ Leprdb/J m 37.4435 0.8285 39.0731 35.8138
BKSChpLt.HRS-Cpefat/J f 22.8947 0.9115 24.6877 21.1017
BKSChpLt.HRS-Cpefat/J m 27.5636 0.8471 29.2299 25.8974
C57BL/6J f 19.305 0.8884 21.0526 17.5574
C57BL/6J m 25.9 0.8884 27.6476 24.1524
C57BLKS/J f 18.7778 0.7646 20.2819 17.2737
C57BLKS/J m 23.7828 0.7378 25.2341 22.3315


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J both 34.6062 0.5565 35.7008 33.5116
B6.Cg-Ay/J both 29.7391 0.5234 30.7686 28.7095
B6.Cg-Lepob/J both 51.5161 0.5576 52.6129 50.4192
BKS.Cg-Dock7m +/+ Leprdb/J both 40.036 0.5591 41.1357 38.9363
BKSChpLt.HRS-Cpefat/J both 25.2292 0.6222 26.453 24.0053
C57BL/6J both 22.6025 0.6282 23.8382 21.3668
C57BLKS/J both 21.2803 0.5313 22.3253 20.2352




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA