Project measure / variable:   Ackert1   bone_area_M12

ID, description, units MPD:25022   bone_area_M12   whole body bone area, head excluded   [cm2]  at age 12mo  
Data set, strains Ackert1   inbred   30 strains     sex: both     age: 52wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Ackert1 - whole body bone area, head excluded at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains28 strains
Mean of the strain means9.19   cm2 9.53   cm2
Median of the strain means9.13   cm2 9.43   cm2
SD of the strain means± 1.06 ± 1.07
Coefficient of variation (CV)0.115 0.113
Min–max range of strain means7.63   –   11.1   cm2 7.81   –   12.5   cm2
Mean sample size per strain7.6   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15.0424 15.0424 33.2872 < 0.0001
strain 26 342.9515 13.1904 29.1891 < 0.0001
sex:strain 26 39.9111 1.535 3.3969 < 0.0001
Residuals 345 155.904 0.4519


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.59 0.116   8 0.0412 0.0122 9.44, 9.75 0.38
129S1/SvImJ m 9.37 0.633   8 0.224 0.0675 8.6, 10.3 -0.15
A/J f 8.07 0.797   8 0.282 0.0989 7.34, 9.75 -1.06
A/J m 7.89 0.352   3 0.203 0.0447 7.56, 8.26 -1.53
AKR/J f 10.6 0.705   3 0.407 0.0665 9.89, 11.3 1.34
BALB/cByJ f 9.03 0.654   8 0.231 0.0724 8.09, 9.95 -0.15
BALB/cByJ m 9.46 0.423   7 0.16 0.0447 9.2, 10.4 -0.07
BTBR T+ Itpr3tf/J f 10.1 1.16   7 0.439 0.115 7.73, 11.4 0.86
BTBR T+ Itpr3tf/J m 10.7 0.344   8 0.122 0.0321 10.1, 11.2 1.09
BUB/BnJ f 9.48 0.798   7 0.302 0.0842 8.7, 10.7 0.28
BUB/BnJ m 9.98 1.04   8 0.369 0.105 8.95, 11.8 0.42
C3H/HeJ f 10.1 0.599   7 0.226 0.0593 9.13, 11.0 0.86
C3H/HeJ m 10.8 0.422   7 0.16 0.039 10.2, 11.3 1.18
C57BL/10J f 8.13 1.02   8 0.362 0.126 6.06, 9.31 -1.0
C57BL/10J m 8.54 0.523   6 0.214 0.0613 7.88, 9.13 -0.92
C57BL/6J f 8.29 0.469   8 0.166 0.0566 7.58, 9.04 -0.85
C57BL/6J m 9.4 0.558   8 0.197 0.0593 8.71, 10.4 -0.12
C57BLKS/J f 8.19 0.393   8 0.139 0.0479 7.68, 8.76 -0.94
C57BLKS/J m 9.06 0.323   8 0.114 0.0357 8.67, 9.59 -0.44
C57BR/cdJ f 10.3 0.246   7 0.0929 0.0239 9.97, 10.6 1.05
C57BR/cdJ m 9.37 0.927   3 0.535 0.0989 8.37, 10.2 -0.15
C57L/J f 9.62 0.679   8 0.24 0.0706 8.73, 10.6 0.41
C57L/J m 9.91 1.36   8 0.482 0.137 8.49, 12.2 0.35
CBA/J f 9.13 0.981   8 0.347 0.107 7.98, 11.3 -0.05
CBA/J m 9.88 0.774   8 0.274 0.0784 9.17, 11.2 0.32
DBA/2J f 7.63 0.391   8 0.138 0.0513 6.91, 8.14 -1.47
DBA/2J m 9.91 0.695   9 0.232 0.0701 8.6, 10.7 0.35
FVB/NJ f 8.84 0.457   7 0.173 0.0517 8.24, 9.27 -0.33
FVB/NJ m 9.81 0.836   9 0.279 0.0852 8.3, 11.0 0.26
KK/HlJ f 9.93 0.822   8 0.291 0.0828 8.88, 11.2 0.7
KK/HlJ m 9.39 0.356   9 0.119 0.0379 8.85, 9.93 -0.13
LP/J f 9.04 0.557   8 0.197 0.0616 8.4, 10.1 -0.14
LP/J m 9.3 0.415   10 0.131 0.0447 8.71, 10.1 -0.22
MRL/MpJ f 11.1 0.277   5 0.124 0.025 10.8, 11.4 1.81
MRL/MpJ m 12.5 1.15   3 0.666 0.0923 11.2, 13.4 2.76
NOD.B10Sn-H2b/J f 11.1 0.348   8 0.123 0.0313 10.8, 11.8 1.81
NOD.B10Sn-H2b/J m 10.8 0.462   8 0.163 0.0426 9.98, 11.4 1.18
NON/ShiLtJ f 9.96 0.406   9 0.135 0.0407 9.25, 10.5 0.73
NON/ShiLtJ m 9.88 0.702   8 0.248 0.071 8.96, 10.8 0.32
NZO/HlLtJ f 10.7 0.91   7 0.344 0.0851 9.57, 11.9 1.43
NZO/HlLtJ m 11.1 1.71   4 0.855 0.155 9.63, 13.5 1.46
NZW/LacJ f 9.71 0.983   9 0.328 0.101 8.39, 11.3 0.49
NZW/LacJ m 9.83 0.459   8 0.162 0.0467 9.27, 10.6 0.28
P/J m 8.63 1.42   3 0.822 0.165 7.43, 10.2 -0.84
PL/J f 7.84 0.312   4 0.156 0.0398 7.38, 8.06 -1.27
PL/J m 7.81 0.449   8 0.159 0.0575 7.31, 8.43 -1.6
PWD/PhJ f 8.1 0.391   9 0.13 0.0483 7.46, 8.81 -1.03
PWD/PhJ m 7.81 0.375   9 0.125 0.048 7.19, 8.31 -1.6
RIIIS/J f 7.63 0.416   8 0.147 0.0545 7.12, 8.19 -1.47
RIIIS/J m 8.44 0.937   8 0.331 0.111 7.52, 10.5 -1.02
SJL/J f 8.72 0.242   8 0.0855 0.0278 8.41, 9.12 -0.44
SM/J f 7.7 0.516   8 0.183 0.0671 6.9, 8.47 -1.4
SM/J m 8.39 0.414   8 0.146 0.0494 7.58, 8.89 -1.06
SWR/J f 9.21 0.411   8 0.145 0.0446 8.46, 9.66 0.02
SWR/J m 10.2 0.582   7 0.22 0.0571 9.38, 11.2 0.62
WSB/EiJ f 8.57 0.842   7 0.318 0.0982 7.58, 9.72 -0.58
WSB/EiJ m 8.73 0.566   4 0.283 0.0648 8.37, 9.58 -0.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.585 0.2377 10.0525 9.1175
129S1/SvImJ m 9.365 0.2377 9.8325 8.8975
A/J f 8.065 0.2377 8.5325 7.5975
A/J m 7.8867 0.3881 8.65 7.1233
BALB/cByJ f 9.0263 0.2377 9.4937 8.5588
BALB/cByJ m 9.4629 0.2541 9.9626 8.9631
BTBR T+ Itpr3tf/J f 10.0714 0.2541 10.5712 9.5717
BTBR T+ Itpr3tf/J m 10.7125 0.2377 11.18 10.245
BUB/BnJ f 9.4843 0.2541 9.984 8.9845
BUB/BnJ m 9.9787 0.2377 10.4462 9.5113
C3H/HeJ f 10.0871 0.2541 10.5869 9.5874
C3H/HeJ m 10.8143 0.2541 11.314 10.3145
C57BL/10J f 8.1262 0.2377 8.5937 7.6588
C57BL/10J m 8.535 0.2744 9.0748 7.9952
C57BL/6J f 8.285 0.2377 8.7525 7.8175
C57BL/6J m 9.4 0.2377 9.8675 8.9325
C57BLKS/J f 8.1937 0.2377 8.6612 7.7263
C57BLKS/J m 9.0612 0.2377 9.5287 8.5938
C57BR/cdJ f 10.2643 0.2541 10.764 9.7645
C57BR/cdJ m 9.37 0.3881 10.1334 8.6066
C57L/J f 9.615 0.2377 10.0825 9.1475
C57L/J m 9.9125 0.2377 10.38 9.445
CBA/J f 9.1313 0.2377 9.5987 8.6638
CBA/J m 9.8825 0.2377 10.35 9.415
DBA/2J f 7.6288 0.2377 8.0962 7.1613
DBA/2J m 9.9122 0.2241 10.353 9.4715
FVB/NJ f 8.8357 0.2541 9.3355 8.336
FVB/NJ m 9.8078 0.2241 10.2485 9.367
KK/HlJ f 9.9312 0.2377 10.3987 9.4638
KK/HlJ m 9.3889 0.2241 9.8296 8.9482
LP/J f 9.0425 0.2377 9.51 8.575
LP/J m 9.296 0.2126 9.7141 8.8779
MRL/MpJ f 11.12 0.3006 11.7113 10.5287
MRL/MpJ m 12.5 0.3881 13.2634 11.7366
NOD.B10Sn-H2b/J f 11.1125 0.2377 11.58 10.645
NOD.B10Sn-H2b/J m 10.835 0.2377 11.3025 10.3675
NON/ShiLtJ f 9.9644 0.2241 10.4052 9.5237
NON/ShiLtJ m 9.8763 0.2377 10.3437 9.4088
NZO/HlLtJ f 10.6957 0.2541 11.1955 10.196
NZO/HlLtJ m 11.0575 0.3361 11.7186 10.3964
NZW/LacJ f 9.7056 0.2241 10.1463 9.2648
NZW/LacJ m 9.835 0.2377 10.3025 9.3675
PL/J f 7.8375 0.3361 8.4986 7.1764
PL/J m 7.8113 0.2377 8.2787 7.3438
PWD/PhJ f 8.0978 0.2241 8.5385 7.657
PWD/PhJ m 7.8078 0.2241 8.2485 7.367
RIIIS/J f 7.63 0.2377 8.0975 7.1625
RIIIS/J m 8.4437 0.2377 8.9112 7.9763
SM/J f 7.6963 0.2377 8.1637 7.2288
SM/J m 8.3863 0.2377 8.8537 7.9188
SWR/J f 9.215 0.2377 9.6825 8.7475
SWR/J m 10.1914 0.2541 10.6912 9.6917
WSB/EiJ f 8.5686 0.2541 9.0683 8.0688
WSB/EiJ m 8.735 0.3361 9.3961 8.0739


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 9.475 0.1681 9.8055 9.1445
A/J both 7.9758 0.2276 8.4234 7.5283
BALB/cByJ both 9.2446 0.174 9.5867 8.9024
BTBR T+ Itpr3tf/J both 10.392 0.174 10.7341 10.0498
BUB/BnJ both 9.7315 0.174 10.0737 9.3894
C3H/HeJ both 10.4507 0.1797 10.8041 10.0973
C57BL/10J both 8.3306 0.1815 8.6877 7.9736
C57BL/6J both 8.8425 0.1681 9.173 8.512
C57BLKS/J both 8.6275 0.1681 8.958 8.297
C57BR/cdJ both 9.8171 0.2319 10.2733 9.3609
C57L/J both 9.7638 0.1681 10.0943 9.4332
CBA/J both 9.5069 0.1681 9.8374 9.1763
DBA/2J both 8.7705 0.1633 9.0917 8.4493
FVB/NJ both 9.3217 0.1694 9.6549 8.9886
KK/HlJ both 9.6601 0.1633 9.9813 9.3388
LP/J both 9.1692 0.1594 9.4828 8.8557
MRL/MpJ both 11.81 0.2455 12.2928 11.3272
NOD.B10Sn-H2b/J both 10.9738 0.1681 11.3043 10.6432
NON/ShiLtJ both 9.9203 0.1633 10.2416 9.5991
NZO/HlLtJ both 10.8766 0.2107 11.291 10.4622
NZW/LacJ both 9.7703 0.1633 10.0915 9.449
PL/J both 7.8244 0.2058 8.2292 7.4195
PWD/PhJ both 7.9528 0.1584 8.2644 7.6411
RIIIS/J both 8.0369 0.1681 8.3674 7.7063
SM/J both 8.0413 0.1681 8.3718 7.7107
SWR/J both 9.7032 0.174 10.0454 9.3611
WSB/EiJ both 8.6518 0.2107 9.0661 8.2374




  GWAS USING LINEAR MIXED MODELS