Phenotype measure:   Ackert1   BMC_M20

ID, description, units MPD:25018   BMC_M20   bone mineral content (BMC)   [g]  at age 20mo
Data set, strains Ackert1   inbred   28 strains     sex: both     age: 87wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Ackert1 - bone mineral content (BMC) at age 20mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains26 strains
Mean of the strain means0.546   g 0.556   g
Median of the strain means0.545   g 0.540   g
SD of the strain means± 0.109 ± 0.111
Coefficient of variation (CV)0.200 0.200
Min–max range of strain means0.384   –   0.810   g 0.395   –   0.801   g
Mean sample size per strain6.9   mice 6.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0026 0.0026 0.9935 0.3197
strain 27 3.3958 0.1258 47.7866 < 0.0001
sex:strain 27 0.339 0.0126 4.7699 < 0.0001
Residuals 309 0.8133 0.0026


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.65 0.0489   8 0.0173 0.0751 0.564, 0.705 0.96
129S1/SvImJ m 0.61 0.0353   7 0.0134 0.0579 0.564, 0.661 0.49
A/J f 0.394 0.0364   3 0.021 0.0924 0.372, 0.436 -1.39
A/J m 0.404 0.0366   4 0.0183 0.0907 0.374, 0.453 -1.36
BALB/cByJ f 0.526 0.0473   5 0.0212 0.09 0.484, 0.6 -0.18
BALB/cByJ m 0.496 0.0525   7 0.0199 0.106 0.42, 0.554 -0.54
BTBR T+ Itpr3tf/J f 0.629 0.0769   6 0.0314 0.122 0.491, 0.69 0.76
BTBR T+ Itpr3tf/J m 0.71 0.0484   3 0.028 0.0682 0.654, 0.742 1.38
BUB/BnJ f 0.508 0.0542   8 0.0191 0.107 0.419, 0.565 -0.35
C3H/HeJ f 0.649 0.0613   6 0.025 0.0945 0.537, 0.707 0.95
C3H/HeJ m 0.736 0.0575   8 0.0203 0.0781 0.656, 0.815 1.62
C57BL/10J f 0.399 0.0673   8 0.0238 0.169 0.315, 0.508 -1.34
C57BL/10J m 0.442 0.0195   7 0.00738 0.0442 0.413, 0.466 -1.02
C57BL/6J f 0.453 0.048   8 0.017 0.106 0.365, 0.505 -0.85
C57BL/6J m 0.548 0.0543   7 0.0205 0.099 0.485, 0.653 -0.07
C57BLKS/J f 0.401 0.0236   7 0.00892 0.0588 0.369, 0.434 -1.33
C57BLKS/J m 0.475 0.0246   7 0.00928 0.0517 0.452, 0.512 -0.73
C57BR/cdJ f 0.633 0.0388   8 0.0137 0.0613 0.577, 0.696 0.8
C57BR/cdJ m 0.53 0.0639   8 0.0226 0.12 0.45, 0.639 -0.23
C57L/J f 0.675 0.0787   8 0.0278 0.117 0.575, 0.799 1.19
C57L/J m 0.597 0.0497   7 0.0188 0.0833 0.534, 0.654 0.37
CBA/J f 0.565 0.0476   8 0.0168 0.0843 0.509, 0.641 0.18
CBA/J m 0.593 0.0664   8 0.0235 0.112 0.502, 0.667 0.33
DBA/2J f 0.415 0.0322   7 0.0122 0.0776 0.365, 0.447 -1.2
DBA/2J m 0.531 0.0266   6 0.0109 0.0501 0.504, 0.575 -0.22
FVB/NJ f 0.512 0.0475   6 0.0194 0.0927 0.458, 0.574 -0.31
FVB/NJ m 0.492 0.0822   5 0.0368 0.167 0.359, 0.583 -0.57
KK/HlJ f 0.627 0.0364   6 0.0149 0.0581 0.583, 0.667 0.75
KK/HlJ m 0.567 0.0466   7 0.0176 0.0822 0.506, 0.639 0.1
LP/J f 0.624 0.031   8 0.011 0.0497 0.587, 0.684 0.72
LP/J m 0.639 0.0316   8 0.0112 0.0495 0.599, 0.686 0.75
MRL/MpJ f 0.81 0.0781   3 0.0451 0.0964 0.75, 0.898 2.42
MRL/MpJ m 0.801 0.0686   4 0.0343 0.0856 0.72, 0.886 2.2
NOD.B10Sn-H2b/J f 0.683 0.0139   8 0.00491 0.0203 0.668, 0.709 1.26
NOD.B10Sn-H2b/J m 0.769 0.047   5 0.021 0.0611 0.717, 0.841 1.91
NON/ShiLtJ f 0.597 0.0274   9 0.00913 0.0459 0.559, 0.644 0.47
NON/ShiLtJ m 0.563 0.031   8 0.011 0.0551 0.518, 0.625 0.06
NZO/HlLtJ f 0.597 0.0441   5 0.0197 0.0739 0.545, 0.646 0.47
NZO/HlLtJ m 0.614 0.0778   4 0.0389 0.127 0.534, 0.698 0.52
NZW/LacJ f 0.633 0.0792   8 0.028 0.125 0.503, 0.743 0.8
NZW/LacJ m 0.629 0.0454   7 0.0172 0.0722 0.552, 0.699 0.66
P/J f 0.43 0.0387   8 0.0137 0.0899 0.374, 0.49 -1.06
P/J m 0.431 0.013   6 0.00529 0.03 0.406, 0.442 -1.12
PL/J f 0.467 0.041   5 0.0183 0.0878 0.42, 0.518 -0.72
PWD/PhJ f 0.448 0.0561   8 0.0198 0.125 0.365, 0.521 -0.9
PWD/PhJ m 0.395 0.0376   7 0.0142 0.0951 0.351, 0.458 -1.45
RIIIS/J f 0.568 0.105   8 0.0373 0.185 0.438, 0.792 0.2
RIIIS/J m 0.483 0.036   8 0.0127 0.0745 0.438, 0.536 -0.66
SM/J f 0.384 0.0201   8 0.00709 0.0522 0.36, 0.416 -1.48
SM/J m 0.444 0.0226   8 0.008 0.0509 0.4, 0.473 -1.01
SWR/J f 0.493 0.0316   4 0.0158 0.0642 0.45, 0.52 -0.48
SWR/J m 0.517 0.0287   7 0.0109 0.0556 0.462, 0.548 -0.35
WSB/EiJ f 0.509 0.0952   8 0.0336 0.187 0.391, 0.676 -0.34
WSB/EiJ m 0.438 0.044   6 0.018 0.1 0.381, 0.488 -1.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6504 0.0181 0.6861 0.6147
129S1/SvImJ m 0.6097 0.0194 0.6479 0.5716
A/J f 0.394 0.0296 0.4523 0.3357
A/J m 0.404 0.0257 0.4545 0.3535
BALB/cByJ f 0.5262 0.0229 0.5713 0.4811
BALB/cByJ m 0.4956 0.0194 0.5337 0.4574
BTBR T+ Itpr3tf/J f 0.629 0.0209 0.6702 0.5878
BTBR T+ Itpr3tf/J m 0.7097 0.0296 0.7679 0.6514
BUB/BnJ f 0.5079 0.0181 0.5436 0.4722
BUB/BnJ m 0.5705 0.0363 0.6419 0.4991
C3H/HeJ f 0.6493 0.0209 0.6905 0.6081
C3H/HeJ m 0.7362 0.0181 0.7719 0.7006
C57BL/10J f 0.3989 0.0181 0.4346 0.3632
C57BL/10J m 0.4419 0.0194 0.48 0.4037
C57BL/6J f 0.4534 0.0181 0.4891 0.4177
C57BL/6J m 0.5484 0.0194 0.5866 0.5103
C57BLKS/J f 0.401 0.0194 0.4392 0.3628
C57BLKS/J m 0.4751 0.0194 0.5133 0.437
C57BR/cdJ f 0.6329 0.0181 0.6686 0.5972
C57BR/cdJ m 0.5301 0.0181 0.5658 0.4944
C57L/J f 0.6748 0.0181 0.7104 0.6391
C57L/J m 0.5973 0.0194 0.6354 0.5591
CBA/J f 0.5655 0.0181 0.6012 0.5298
CBA/J m 0.5925 0.0181 0.6282 0.5568
DBA/2J f 0.4151 0.0194 0.4533 0.377
DBA/2J m 0.531 0.0209 0.5722 0.4898
FVB/NJ f 0.5117 0.0209 0.5529 0.4705
FVB/NJ m 0.4922 0.0229 0.5373 0.4471
KK/HlJ f 0.6268 0.0209 0.668 0.5856
KK/HlJ m 0.5667 0.0194 0.6049 0.5286
LP/J f 0.624 0.0181 0.6597 0.5883
LP/J m 0.6388 0.0181 0.6744 0.6031
MRL/MpJ f 0.8097 0.0296 0.8679 0.7514
MRL/MpJ m 0.8015 0.0257 0.852 0.751
NOD.B10Sn-H2b/J f 0.6826 0.0181 0.7183 0.6469
NOD.B10Sn-H2b/J m 0.7692 0.0229 0.8143 0.7241
NON/ShiLtJ f 0.5966 0.0171 0.6302 0.5629
NON/ShiLtJ m 0.5629 0.0181 0.5986 0.5272
NZO/HlLtJ f 0.5966 0.0229 0.6417 0.5515
NZO/HlLtJ m 0.6142 0.0257 0.6647 0.5638
NZW/LacJ f 0.6334 0.0181 0.6691 0.5977
NZW/LacJ m 0.6289 0.0194 0.667 0.5907
P/J f 0.4303 0.0181 0.4659 0.3946
P/J m 0.4312 0.0209 0.4724 0.39
PL/J f 0.467 0.0229 0.5121 0.4219
PL/J m 0.4625 0.0363 0.5339 0.3911
PWD/PhJ f 0.4479 0.0181 0.4836 0.4122
PWD/PhJ m 0.3954 0.0194 0.4336 0.3573
RIIIS/J f 0.5684 0.0181 0.6041 0.5327
RIIIS/J m 0.483 0.0181 0.5187 0.4473
SM/J f 0.3841 0.0181 0.4198 0.3484
SM/J m 0.4444 0.0181 0.4801 0.4087
SWR/J f 0.4928 0.0257 0.5432 0.4423
SWR/J m 0.517 0.0194 0.5552 0.4788
WSB/EiJ f 0.5091 0.0181 0.5448 0.4734
WSB/EiJ m 0.4377 0.0209 0.4789 0.3965


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.63 0.0133 0.6562 0.6039
A/J both 0.399 0.0196 0.4375 0.3605
BALB/cByJ both 0.5109 0.015 0.5404 0.4813
BTBR T+ Itpr3tf/J both 0.6693 0.0181 0.705 0.6336
BUB/BnJ both 0.5392 0.0203 0.5791 0.4993
C3H/HeJ both 0.6928 0.0139 0.7201 0.6655
C57BL/10J both 0.4204 0.0133 0.4465 0.3942
C57BL/6J both 0.5009 0.0133 0.527 0.4748
C57BLKS/J both 0.4381 0.0137 0.4651 0.4111
C57BR/cdJ both 0.5815 0.0128 0.6067 0.5563
C57L/J both 0.636 0.0133 0.6621 0.6099
CBA/J both 0.579 0.0128 0.6042 0.5538
DBA/2J both 0.4731 0.0143 0.5012 0.445
FVB/NJ both 0.5019 0.0155 0.5325 0.4714
KK/HlJ both 0.5968 0.0143 0.6249 0.5687
LP/J both 0.6314 0.0128 0.6566 0.6061
MRL/MpJ both 0.8056 0.0196 0.8441 0.767
NOD.B10Sn-H2b/J both 0.7259 0.0146 0.7547 0.6971
NON/ShiLtJ both 0.5797 0.0125 0.6042 0.5552
NZO/HlLtJ both 0.6054 0.0172 0.6393 0.5716
NZW/LacJ both 0.6311 0.0133 0.6572 0.605
P/J both 0.4307 0.0139 0.458 0.4034
PL/J both 0.4648 0.0215 0.507 0.4225
PWD/PhJ both 0.4217 0.0133 0.4478 0.3955
RIIIS/J both 0.5257 0.0128 0.5509 0.5005
SM/J both 0.4142 0.0128 0.4395 0.389
SWR/J both 0.5049 0.0161 0.5365 0.4732
WSB/EiJ both 0.4734 0.0139 0.5007 0.4461




  GWAS USING LINEAR MIXED MODELS