Phenotype measure:   Ackert1   BMC_M06

ID, description, units MPD:25016   BMC_M06   bone mineral content (BMC)   [g]  at age 6mo
Data set, strains Ackert1   inbred   31 strains     sex: both     age: 26wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Ackert1 - bone mineral content (BMC) at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains30 strains
Mean of the strain means0.588   g 0.582   g
Median of the strain means0.576   g 0.567   g
SD of the strain means± 0.119 ± 0.103
Coefficient of variation (CV)0.202 0.177
Min–max range of strain means0.345   –   0.843   g 0.431   –   0.845   g
Mean sample size per strain7.0   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0 0.0 0.0075 0.9312
strain 30 4.1296 0.1377 59.1931 < 0.0001
sex:strain 30 0.7359 0.0245 10.5481 < 0.0001
Residuals 344 0.8 0.0023


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.688 0.0438   8 0.0155 0.0636 0.619, 0.739 0.84
129S1/SvImJ m 0.743 0.101   7 0.038 0.135 0.576, 0.893 1.55
A/J f 0.425 0.04   8 0.0141 0.094 0.378, 0.493 -1.37
A/J m 0.481 0.0439   8 0.0155 0.0912 0.427, 0.547 -0.98
AKR/J f 0.646 0.0396   6 0.0162 0.0613 0.576, 0.684 0.49
AKR/J m 0.702 0.0377   5 0.0169 0.0537 0.641, 0.735 1.16
BALB/cByJ f 0.638 0.04   6 0.0163 0.0627 0.598, 0.694 0.42
BALB/cByJ m 0.585 0.0816   6 0.0333 0.139 0.478, 0.708 0.02
BTBR T+ Itpr3tf/J f 0.73 0.0261   5 0.0117 0.0357 0.686, 0.748 1.2
BTBR T+ Itpr3tf/J m 0.73 0.0202   7 0.00762 0.0276 0.703, 0.756 1.43
BUB/BnJ f 0.731 0.0605   8 0.0214 0.0827 0.641, 0.796 1.21
BUB/BnJ m 0.69 0.0495   4 0.0248 0.0718 0.634, 0.75 1.04
C3H/HeJ f 0.764 0.0294   8 0.0104 0.0385 0.735, 0.821 1.48
C3H/HeJ m 0.726 0.0852   6 0.0348 0.117 0.619, 0.841 1.39
C57BL/10J f 0.484 0.0396   8 0.014 0.0819 0.42, 0.528 -0.87
C57BL/10J m 0.549 0.0277   6 0.0113 0.0504 0.512, 0.583 -0.32
C57BL/6J f 0.509 0.0275   8 0.00971 0.054 0.481, 0.55 -0.66
C57BL/6J m 0.647 0.0609   8 0.0215 0.0942 0.561, 0.71 0.62
C57BLKS/J f 0.441 0.023   8 0.00814 0.0521 0.409, 0.485 -1.23
C57BLKS/J m 0.5 0.0345   8 0.0122 0.069 0.452, 0.559 -0.8
C57BR/cdJ f 0.74 0.0804   7 0.0304 0.109 0.672, 0.864 1.28
C57BR/cdJ m 0.542 0.0715   6 0.0292 0.132 0.436, 0.608 -0.39
C57L/J f 0.664 0.0708   7 0.0268 0.107 0.577, 0.805 0.64
C57L/J m 0.537 0.0266   5 0.0119 0.0495 0.518, 0.579 -0.44
CAST/EiJ f 0.458 0.0536   6 0.0219 0.117 0.365, 0.52 -1.09
CAST/EiJ m 0.468 0.0415   7 0.0157 0.0886 0.424, 0.516 -1.11
CBA/J f 0.601 0.0232   8 0.00821 0.0387 0.579, 0.648 0.11
CBA/J m 0.62 0.0184   4 0.0092 0.0297 0.607, 0.647 0.36
DBA/2J f 0.467 0.0231   5 0.0104 0.0496 0.43, 0.493 -1.01
DBA/2J m 0.656 0.0743   7 0.0281 0.113 0.548, 0.746 0.71
FVB/NJ f 0.546 0.0689   8 0.0243 0.126 0.465, 0.677 -0.35
FVB/NJ m 0.638 0.0686   6 0.028 0.108 0.586, 0.754 0.54
KK/HlJ f 0.647 0.0646   4 0.0323 0.0999 0.56, 0.705 0.5
KK/HlJ m 0.563 0.0447   7 0.0169 0.0793 0.491, 0.606 -0.19
LP/J f 0.596 0.0396   6 0.0162 0.0664 0.548, 0.646 0.07
LP/J m 0.571 0.0422   8 0.0149 0.0738 0.524, 0.649 -0.11
MOLF/EiJ f 0.489 0.0378   7 0.0143 0.0773 0.442, 0.557 -0.83
MOLF/EiJ m 0.452 0.0244   7 0.00923 0.054 0.413, 0.49 -1.26
MRL/MpJ f 0.843 0.048   3 0.0277 0.0569 0.803, 0.896 2.15
MRL/MpJ m 0.845 0.0461   7 0.0174 0.0545 0.794, 0.91 2.54
NOD.B10Sn-H2b/J f 0.783 0.0232   8 0.00822 0.0297 0.75, 0.813 1.64
NON/ShiLtJ f 0.615 0.0283   8 0.00999 0.046 0.564, 0.654 0.23
NON/ShiLtJ m 0.605 0.0402   7 0.0152 0.0664 0.545, 0.66 0.22
NZW/LacJ f 0.576 0.0581   8 0.0206 0.101 0.489, 0.676 -0.1
NZW/LacJ m 0.649 0.0444   5 0.0198 0.0684 0.607, 0.718 0.64
P/J f 0.575 0.0429   6 0.0175 0.0745 0.517, 0.625 -0.11
P/J m 0.483 0.0282   6 0.0115 0.0584 0.447, 0.518 -0.96
PL/J f 0.484 0.0353   8 0.0125 0.0729 0.439, 0.556 -0.87
PL/J m 0.462 0.0268   8 0.00948 0.0581 0.426, 0.514 -1.17
PWD/PhJ f 0.534 0.0302   5 0.0135 0.0566 0.51, 0.577 -0.45
PWD/PhJ m 0.48 0.0275   4 0.0137 0.0573 0.448, 0.515 -0.99
RIIIS/J f 0.565 0.0517   8 0.0183 0.0916 0.484, 0.623 -0.19
RIIIS/J m 0.469 0.0323   6 0.0132 0.0688 0.431, 0.51 -1.1
SJL/J f 0.616 0.0809   8 0.0286 0.131 0.508, 0.745 0.24
SJL/J m 0.544 0.0282   6 0.0115 0.0518 0.513, 0.58 -0.37
SM/J f 0.345 0.0452   8 0.016 0.131 0.27, 0.394 -2.04
SM/J m 0.533 0.0448   8 0.0158 0.0841 0.445, 0.595 -0.48
SWR/J f 0.555 0.0319   6 0.013 0.0576 0.503, 0.59 -0.27
SWR/J m 0.574 0.0345   6 0.0141 0.0601 0.524, 0.605 -0.08
WSB/EiJ f 0.46 0.0558   6 0.0228 0.121 0.361, 0.517 -1.07
WSB/EiJ m 0.431 0.0155   6 0.00631 0.0359 0.413, 0.459 -1.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6884 0.017 0.7219 0.6548
129S1/SvImJ m 0.743 0.0182 0.7788 0.7072
A/J f 0.4251 0.017 0.4587 0.3916
A/J m 0.481 0.017 0.5145 0.4475
AKR/J f 0.6457 0.0197 0.6844 0.6069
AKR/J m 0.7022 0.0216 0.7446 0.6598
BALB/cByJ f 0.6383 0.0197 0.6771 0.5996
BALB/cByJ m 0.5852 0.0197 0.6239 0.5464
BTBR T+ Itpr3tf/J f 0.7304 0.0216 0.7728 0.688
BTBR T+ Itpr3tf/J m 0.7301 0.0182 0.766 0.6943
BUB/BnJ f 0.7313 0.017 0.7648 0.6977
BUB/BnJ m 0.6898 0.0241 0.7372 0.6423
C3H/HeJ f 0.7638 0.017 0.7973 0.7302
C3H/HeJ m 0.7257 0.0197 0.7644 0.6869
C57BL/10J f 0.4839 0.017 0.5174 0.4503
C57BL/10J m 0.5495 0.0197 0.5882 0.5108
C57BL/6J f 0.5086 0.017 0.5422 0.4751
C57BL/6J m 0.6466 0.017 0.6802 0.6131
C57BLKS/J f 0.4414 0.017 0.4749 0.4078
C57BLKS/J m 0.5 0.017 0.5335 0.4665
C57BR/cdJ f 0.7397 0.0182 0.7756 0.7039
C57BR/cdJ m 0.5418 0.0197 0.5806 0.5031
C57L/J f 0.664 0.0182 0.6998 0.6282
C57L/J m 0.537 0.0216 0.5794 0.4946
CAST/EiJ f 0.4577 0.0197 0.4964 0.4189
CAST/EiJ m 0.4684 0.0182 0.5043 0.4326
CBA/J f 0.6006 0.017 0.6342 0.5671
CBA/J m 0.6198 0.0241 0.6672 0.5723
DBA/2J f 0.4668 0.0216 0.5092 0.4244
DBA/2J m 0.6556 0.0182 0.6914 0.6197
FVB/NJ f 0.5464 0.017 0.5799 0.5128
FVB/NJ m 0.6377 0.0197 0.6764 0.5989
KK/HlJ f 0.6472 0.0241 0.6947 0.5998
KK/HlJ m 0.5633 0.0182 0.5991 0.5274
LP/J f 0.5963 0.0197 0.6351 0.5576
LP/J m 0.5712 0.017 0.6048 0.5377
MOLF/EiJ f 0.4886 0.0182 0.5244 0.4527
MOLF/EiJ m 0.452 0.0182 0.4878 0.4162
MRL/MpJ f 0.8427 0.0278 0.8974 0.7879
MRL/MpJ m 0.8449 0.0182 0.8807 0.809
NOD.B10Sn-H2b/J f 0.7832 0.017 0.8168 0.7497
NOD.B10Sn-H2b/J m 0.718 0.0341 0.7851 0.6509
NON/ShiLtJ f 0.6151 0.017 0.6487 0.5816
NON/ShiLtJ m 0.6049 0.0182 0.6407 0.569
NZW/LacJ f 0.5763 0.017 0.6098 0.5427
NZW/LacJ m 0.649 0.0216 0.6914 0.6066
P/J f 0.575 0.0197 0.6137 0.5363
P/J m 0.4827 0.0197 0.5214 0.4439
PL/J f 0.4841 0.017 0.5177 0.4506
PL/J m 0.4618 0.017 0.4953 0.4282
PWD/PhJ f 0.5338 0.0216 0.5762 0.4914
PWD/PhJ m 0.4795 0.0241 0.5269 0.4321
RIIIS/J f 0.5645 0.017 0.598 0.531
RIIIS/J m 0.4693 0.0197 0.5081 0.4306
SJL/J f 0.616 0.017 0.6495 0.5825
SJL/J m 0.5437 0.0197 0.5824 0.5049
SM/J f 0.3454 0.017 0.3789 0.3118
SM/J m 0.5328 0.017 0.5663 0.4992
SWR/J f 0.555 0.0197 0.5937 0.5163
SWR/J m 0.5738 0.0197 0.6126 0.5351
WSB/EiJ f 0.4598 0.0197 0.4986 0.4211
WSB/EiJ m 0.4308 0.0197 0.4696 0.3921


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.7157 0.0125 0.7402 0.6911
A/J both 0.4531 0.0121 0.4768 0.4293
AKR/J both 0.6739 0.0146 0.7027 0.6452
BALB/cByJ both 0.6117 0.0139 0.6391 0.5844
BTBR T+ Itpr3tf/J both 0.7303 0.0141 0.758 0.7025
BUB/BnJ both 0.7105 0.0148 0.7395 0.6815
C3H/HeJ both 0.7447 0.013 0.7703 0.7191
C57BL/10J both 0.5167 0.013 0.5423 0.4911
C57BL/6J both 0.5776 0.0121 0.6013 0.5539
C57BLKS/J both 0.4707 0.0121 0.4944 0.447
C57BR/cdJ both 0.6408 0.0134 0.6672 0.6144
C57L/J both 0.6005 0.0141 0.6283 0.5727
CAST/EiJ both 0.463 0.0134 0.4894 0.4367
CBA/J both 0.6102 0.0148 0.6392 0.5811
DBA/2J both 0.5612 0.0141 0.589 0.5334
FVB/NJ both 0.592 0.013 0.6176 0.5664
KK/HlJ both 0.6053 0.0151 0.635 0.5755
LP/J both 0.5838 0.013 0.6094 0.5582
MOLF/EiJ both 0.4703 0.0129 0.4956 0.4449
MRL/MpJ both 0.8438 0.0166 0.8765 0.811
NOD.B10Sn-H2b/J both 0.7506 0.0191 0.7881 0.7131
NON/ShiLtJ both 0.61 0.0125 0.6345 0.5854
NZW/LacJ both 0.6126 0.0137 0.6397 0.5856
P/J both 0.5288 0.0139 0.5562 0.5015
PL/J both 0.4729 0.0121 0.4967 0.4492
PWD/PhJ both 0.5066 0.0162 0.5385 0.4748
RIIIS/J both 0.5169 0.013 0.5425 0.4913
SJL/J both 0.5798 0.013 0.6054 0.5542
SM/J both 0.4391 0.0121 0.4628 0.4153
SWR/J both 0.5644 0.0139 0.5918 0.537
WSB/EiJ both 0.4453 0.0139 0.4727 0.418




  GWAS USING LINEAR MIXED MODELS