Project measure / variable:   Xing1   ST_M20

ID, description, units MPD:24943   ST_M20   interval ST   [ms]  at age 20mo  
Data set, strains Xing1   inbred   27 strains     sex: both     age: 87wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Xing1 - interval ST at age 20mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means32.3   ms 32.5   ms
Median of the strain means32.2   ms 32.6   ms
SD of the strain means± 2.41 ± 2.14
Coefficient of variation (CV)0.0745 0.0658
Min–max range of strain means25.0   –   35.5   ms 25.0   –   36.2   ms
Mean sample size per strain7.2   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25.3421 25.3421 2.9106 0.089
strain 25 1253.8755 50.155 5.7604 < 0.0001
sex:strain 25 264.3757 10.575 1.2146 0.2229
Residuals 321 2794.9254 8.7069


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 35.0 4.12   8 1.46 0.118 30.8, 41.1 1.13
129S1/SvImJ m 32.9 2.46   8 0.87 0.0748 29.0, 36.4 0.17
A/J f 31.8 2.0   7 0.756 0.0629 28.9, 35.0 -0.2
A/J m 34.2 4.19   9 1.4 0.123 29.1, 40.9 0.78
BALB/cByJ f 33.3 2.16   9 0.72 0.065 28.5, 35.7 0.43
BALB/cByJ m 31.8 2.4   8 0.848 0.0756 27.6, 35.0 -0.34
BTBR T+ Itpr3tf/J f 30.6 2.27   7 0.859 0.0742 27.8, 33.8 -0.7
BTBR T+ Itpr3tf/J m 31.8 2.05   7 0.774 0.0645 29.9, 34.2 -0.34
BUB/BnJ f 30.7 3.47   8 1.23 0.113 25.1, 33.8 -0.66
BUB/BnJ m 25.0 0.0   1   0.0 0.0 25.0, 25.0 -3.52
C3H/HeJ f 28.1 3.86   8 1.36 0.137 22.8, 34.9 -1.74
C3H/HeJ m 29.8 2.93   8 1.04 0.0984 25.0, 32.7 -1.28
C57BL/10J f 30.5 3.66   8 1.29 0.12 25.9, 37.7 -0.74
C57BL/10J m 32.5 3.98   8 1.41 0.123 28.0, 39.3 -0.02
C57BL/6J f 32.2 3.57   6 1.46 0.111 27.6, 36.0 -0.03
C57BL/6J m 33.8 2.04   8 0.722 0.0604 31.3, 38.0 0.59
C57BLKS/J f 33.0 2.23   8 0.788 0.0676 29.8, 36.5 0.3
C57BLKS/J m 33.0 3.46   8 1.23 0.105 26.7, 37.3 0.22
C57BR/cdJ f 32.4 1.34   8 0.473 0.0413 30.0, 34.0 0.05
C57BR/cdJ m 32.3 1.48   8 0.524 0.0459 30.1, 34.5 -0.11
C57L/J f 33.9 1.7   6 0.692 0.0499 32.0, 36.1 0.67
C57L/J m 33.0 2.52   9 0.841 0.0765 28.2, 37.4 0.22
CBA/J f 32.2 1.6   9 0.535 0.0499 30.0, 34.5 -0.03
CBA/J m 33.8 4.21   8 1.49 0.125 25.4, 40.5 0.59
DBA/2J f 33.8 2.9   7 1.1 0.086 29.9, 39.1 0.63
DBA/2J m 32.8 1.69   6 0.691 0.0516 30.6, 34.6 0.12
FVB/NJ f 33.8 2.63   7 0.994 0.0779 29.6, 37.5 0.63
FVB/NJ m 32.9 2.16   7 0.818 0.0659 30.3, 35.9 0.17
KK/HlJ f 34.8 3.69   6 1.51 0.106 28.5, 39.2 1.05
KK/HlJ m 32.3 2.69   7 1.02 0.0833 27.3, 35.4 -0.11
LP/J f 32.1 1.6   8 0.564 0.0497 30.5, 34.7 -0.07
LP/J m 32.2 1.37   9 0.458 0.0426 29.7, 33.9 -0.16
MRL/MpJ f 34.7 2.62   3 1.51 0.0755 32.5, 37.6 1.01
MRL/MpJ m 33.6 6.25   4 3.12 0.186 27.8, 40.7 0.5
NOD.B10Sn-H2b/J f 30.1 1.92   8 0.679 0.0638 27.3, 33.7 -0.91
NOD.B10Sn-H2b/J m 31.4 3.05   8 1.08 0.097 28.0, 35.9 -0.53
NON/ShiLtJ f 34.5 3.93   7 1.48 0.114 28.9, 39.4 0.92
NON/ShiLtJ m 36.0 1.6   7 0.605 0.0445 33.1, 38.5 1.62
NZO/HlLtJ f 32.0 3.95   6 1.61 0.124 29.3, 39.8 -0.12
NZO/HlLtJ m 31.6 2.05   5 0.919 0.0651 28.8, 33.6 -0.44
NZW/LacJ f 31.8 2.09   8 0.74 0.0658 28.0, 34.6 -0.2
NZW/LacJ m 32.6 2.47   8 0.873 0.0757 28.9, 36.9 0.03
P/J f 35.2 5.11   8 1.81 0.145 27.8, 43.7 1.22
P/J m 36.2 3.97   6 1.62 0.11 29.8, 41.3 1.71
PL/J f 31.4 2.43   5 1.09 0.0773 27.3, 33.3 -0.36
PL/J m 32.5 2.62   2   1.85 0.0806 30.6, 34.3 -0.02
PWD/PhJ f 25.0 4.37   8 1.54 0.175 19.6, 30.7 -3.03
PWD/PhJ m 30.8 4.11   7 1.55 0.133 22.6, 36.4 -0.81
RIIIS/J f 35.5 3.99   8 1.41 0.112 31.3, 41.5 1.34
RIIIS/J m 35.7 1.17   8 0.415 0.0329 34.3, 37.7 1.48
SM/J f 34.0 2.52   8 0.89 0.074 30.3, 38.1 0.72
SM/J m 33.5 1.98   8 0.702 0.0592 29.6, 35.5 0.45
SWR/J f 29.1 1.93   4 0.967 0.0666 27.5, 31.5 -1.32
SWR/J m 30.5 1.29   7 0.486 0.0421 29.0, 32.4 -0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 35.025 1.0432 37.0775 32.9725
129S1/SvImJ m 32.9 1.0432 34.9525 30.8475
A/J f 31.8 1.1153 33.9942 29.6058
A/J m 34.2 0.9836 36.1351 32.2649
BALB/cByJ f 33.2556 0.9836 35.1906 31.3205
BALB/cByJ m 31.75 1.0432 33.8025 29.6975
BTBR T+ Itpr3tf/J f 30.6143 1.1153 32.8085 28.4201
BTBR T+ Itpr3tf/J m 31.7857 1.1153 33.9799 29.5915
C3H/HeJ f 28.125 1.0432 30.1775 26.0725
C3H/HeJ m 29.7875 1.0432 31.84 27.735
C57BL/10J f 30.45 1.0432 32.5025 28.3975
C57BL/10J m 32.475 1.0432 34.5275 30.4225
C57BL/6J f 32.2167 1.2046 34.5867 29.8467
C57BL/6J m 33.8 1.0432 35.8525 31.7475
C57BLKS/J f 32.95 1.0432 35.0025 30.8975
C57BLKS/J m 33.0375 1.0432 35.09 30.985
C57BR/cdJ f 32.375 1.0432 34.4275 30.3225
C57BR/cdJ m 32.2625 1.0432 34.315 30.21
C57L/J f 33.95 1.2046 36.32 31.58
C57L/J m 33.0 0.9836 34.9351 31.0649
CBA/J f 32.1778 0.9836 34.1129 30.2427
CBA/J m 33.7875 1.0432 35.84 31.735
DBA/2J f 33.7714 1.1153 35.9656 31.5772
DBA/2J m 32.7833 1.2046 35.1533 30.4133
FVB/NJ f 33.7571 1.1153 35.9513 31.563
FVB/NJ m 32.8571 1.1153 35.0513 30.663
KK/HlJ f 34.7833 1.2046 37.1533 32.4133
KK/HlJ m 32.2571 1.1153 34.4513 30.063
LP/J f 32.1125 1.0432 34.165 30.06
LP/J m 32.2 0.9836 34.1351 30.2649
MRL/MpJ f 34.7 1.7036 38.0517 31.3483
MRL/MpJ m 33.575 1.4754 36.4776 30.6724
NOD.B10Sn-H2b/J f 30.0875 1.0432 32.14 28.035
NOD.B10Sn-H2b/J m 31.4 1.0432 33.4525 29.3475
NON/ShiLtJ f 34.4857 1.1153 36.6799 32.2915
NON/ShiLtJ m 36.0286 1.1153 38.2228 33.8344
NZO/HlLtJ f 31.9667 1.2046 34.3367 29.5967
NZO/HlLtJ m 31.56 1.3196 34.1562 28.9638
NZW/LacJ f 31.7875 1.0432 33.84 29.735
NZW/LacJ m 32.6125 1.0432 34.665 30.56
P/J f 35.15 1.0432 37.2025 33.0975
P/J m 36.2 1.2046 38.57 33.83
PL/J f 31.42 1.3196 34.0162 28.8238
PL/J m 32.45 2.0865 36.5549 28.3451
PWD/PhJ f 24.975 1.0432 27.0275 22.9225
PWD/PhJ m 30.7714 1.1153 32.9656 28.5772
RIIIS/J f 35.4875 1.0432 37.54 33.435
RIIIS/J m 35.725 1.0432 37.7775 33.6725
SM/J f 33.9875 1.0432 36.04 31.935
SM/J m 33.55 1.0432 35.6025 31.4975
SWR/J f 29.05 1.4754 31.9526 26.1474
SWR/J m 30.5286 1.1153 32.7228 28.3344


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 33.9625 0.7377 35.4138 32.5112
A/J both 33.0 0.7435 34.4628 31.5372
BALB/cByJ both 32.5028 0.7169 33.9132 31.0924
BTBR T+ Itpr3tf/J both 31.2 0.7886 32.7515 29.6485
C3H/HeJ both 28.9562 0.7377 30.4076 27.5049
C57BL/10J both 31.4625 0.7377 32.9138 30.0112
C57BL/6J both 33.0083 0.7968 34.5759 31.4407
C57BLKS/J both 32.9937 0.7377 34.4451 31.5424
C57BR/cdJ both 32.3187 0.7377 33.7701 30.8674
C57L/J both 33.475 0.7776 35.0048 31.9452
CBA/J both 32.9826 0.7169 34.3931 31.5722
DBA/2J both 33.2774 0.8208 34.8923 31.6625
FVB/NJ both 33.3071 0.7886 34.8587 31.7556
KK/HlJ both 33.5202 0.8208 35.1351 31.9054
LP/J both 32.1562 0.7169 33.5667 30.7458
MRL/MpJ both 34.1375 1.1268 36.3544 31.9206
NOD.B10Sn-H2b/J both 30.7437 0.7377 32.1951 29.2924
NON/ShiLtJ both 35.2571 0.7886 36.8087 33.7056
NZO/HlLtJ both 31.7633 0.8934 33.521 30.0057
NZW/LacJ both 32.2 0.7377 33.6513 30.7487
P/J both 35.675 0.7968 37.2426 34.1074
PL/J both 31.935 1.2344 34.3635 29.5065
PWD/PhJ both 27.8732 0.7636 29.3755 26.371
RIIIS/J both 35.6062 0.7377 37.0576 34.1549
SM/J both 33.7687 0.7377 35.2201 32.3174
SWR/J both 29.7893 0.9247 31.6086 27.97




  GWAS USING LINEAR MIXED MODELS