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Project measure / variable:   Xing1   ST_M12

ID, description, units MPD:24942   ST_M12   interval ST   [ms]  at age 12mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 52wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Xing1 - interval ST at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means32.8   ms 33.0   ms
Median of the strain means32.7   ms 32.9   ms
SD of the strain means± 2.08 ± 1.74
Coefficient of variation (CV)0.0633 0.0527
Min–max range of strain means28.4   –   38.6   ms 29.4   –   36.2   ms
Mean sample size per strain7.5   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.7507 3.7507 0.3645 0.5464
strain 25 897.3854 35.8954 3.4881 < 0.0001
sex:strain 25 399.4126 15.9765 1.5525 0.0466
Residuals 338 3478.339 10.2909


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 34.5 2.41   8 0.851 0.0698 30.6, 37.4 0.8
129S1/SvImJ m 33.5 6.27   8 2.22 0.187 19.4, 39.9 0.31
A/J f 33.6 5.0   7 1.89 0.149 27.3, 41.0 0.36
A/J m 35.0 2.85   7 1.08 0.0814 31.8, 38.7 1.18
AKR/J f 38.6 16.6   4 8.3 0.43 28.8, 63.4 2.77
AKR/J m 30.6 2.4   5 1.07 0.0783 28.6, 33.9 -1.36
BALB/cByJ f 32.1 2.1   6 0.855 0.0653 29.3, 34.5 -0.36
BALB/cByJ m 35.1 3.95   8 1.4 0.112 31.5, 43.3 1.23
BTBR T+ Itpr3tf/J f 32.0 1.84   8 0.65 0.0575 29.9, 34.5 -0.41
BTBR T+ Itpr3tf/J m 33.6 1.93   8 0.683 0.0575 31.4, 37.5 0.37
BUB/BnJ f 30.8 1.71   7 0.646 0.0555 28.5, 33.5 -0.98
BUB/BnJ m 29.4 3.2   8 1.13 0.109 24.0, 33.1 -2.05
C3H/HeJ f 28.4 1.74   8 0.614 0.0612 26.3, 30.9 -2.14
C3H/HeJ m 30.1 3.38   8 1.19 0.112 24.9, 34.6 -1.64
C57BL/10J f 33.9 2.15   8 0.76 0.0633 30.4, 37.4 0.51
C57BL/10J m 31.7 2.93   8 1.04 0.0925 26.1, 35.4 -0.72
C57BL/6J f 32.9 1.86   7 0.701 0.0564 31.1, 36.3 0.03
C57BL/6J m 32.9 0.807   8 0.285 0.0245 31.6, 34.3 -0.03
C57BLKS/J f 32.7 1.98   8 0.701 0.0607 30.4, 36.5 -0.07
C57BLKS/J m 34.9 0.68   8 0.24 0.0195 33.9, 36.0 1.12
C57BR/cdJ f 32.3 1.89   6 0.772 0.0586 29.4, 34.6 -0.26
C57BR/cdJ m 32.1 1.17   8 0.414 0.0365 29.7, 33.6 -0.49
C57L/J f 33.5 1.79   7 0.675 0.0534 32.3, 37.4 0.32
C57L/J m 33.5 1.22   8 0.432 0.0365 31.9, 35.4 0.31
CBA/J f 33.1 3.21   8 1.13 0.0969 29.9, 38.3 0.12
CBA/J m 33.1 4.98   8 1.76 0.151 25.6, 40.9 0.08
DBA/2J f 30.6 2.27   7 0.858 0.0741 28.3, 33.5 -1.08
DBA/2J m 31.5 1.8   8 0.638 0.0573 28.9, 35.0 -0.84
FVB/NJ f 32.9 3.85   8 1.36 0.117 27.5, 38.3 0.03
FVB/NJ m 32.7 2.37   8 0.839 0.0725 29.3, 36.2 -0.15
KK/HlJ f 32.4 3.05   8 1.08 0.0942 28.4, 38.0 -0.21
KK/HlJ m 32.0 1.81   9 0.602 0.0565 28.8, 34.6 -0.55
LP/J f 32.1 2.06   7 0.78 0.0642 29.4, 34.5 -0.36
LP/J m 32.7 2.02   8 0.713 0.0616 29.6, 35.5 -0.15
MRL/MpJ f 34.6 3.73   7 1.41 0.108 28.1, 40.3 0.84
MRL/MpJ m 31.3 4.72   6 1.93 0.151 23.4, 37.3 -0.95
NOD.B10Sn-H2b/J f 31.5 2.32   10 0.734 0.0737 28.6, 36.1 -0.65
NOD.B10Sn-H2b/J m 30.9 2.4   8 0.848 0.0775 27.7, 34.4 -1.18
NON/ShiLtJ f 33.8 3.0   7 1.14 0.089 30.1, 37.4 0.46
NON/ShiLtJ m 36.2 3.04   8 1.07 0.0839 31.4, 40.7 1.87
NZO/HlLtJ f 32.8 4.0   9 1.33 0.122 29.1, 41.8 -0.02
NZO/HlLtJ m 34.6 2.95   5 1.32 0.0852 30.8, 39.0 0.95
NZW/LacJ f 32.5 2.89   8 1.02 0.0892 27.7, 37.2 -0.17
NZW/LacJ m 34.6 2.21   7 0.834 0.0639 31.7, 38.3 0.95
P/J m 33.6 3.41   6 1.39 0.101 28.7, 38.3 0.37
PL/J f 30.7 1.77   8 0.627 0.0578 27.2, 33.1 -1.03
PL/J m 32.1 1.95   7 0.738 0.0607 29.3, 35.5 -0.49
RIIIS/J f 37.9 3.68   7 1.39 0.0971 33.1, 43.0 2.43
RIIIS/J m 35.9 2.5   8 0.883 0.0697 30.0, 38.3 1.69
SJL/J f 31.6 4.93   8 1.74 0.156 23.5, 39.7 -0.6
SM/J f 34.1 2.05   7 0.777 0.0603 30.7, 37.3 0.6
SM/J m 32.7 2.91   8 1.03 0.0888 27.6, 35.9 -0.15
SWR/J f 30.9 1.34   8 0.474 0.0434 28.7, 33.2 -0.94
SWR/J m 33.5 2.22   7 0.838 0.0661 31.2, 37.9 0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 34.5 1.1342 36.7309 32.2691
129S1/SvImJ m 33.525 1.1342 35.7559 31.2941
A/J f 33.6286 1.2125 36.0136 31.2436
A/J m 34.9857 1.2125 37.3707 32.6007
AKR/J f 38.625 1.604 41.78 35.47
AKR/J m 30.6 1.4346 33.4219 27.7781
BALB/cByJ f 32.0833 1.3096 34.6594 29.5073
BALB/cByJ m 35.1125 1.1342 37.3434 32.8816
BTBR T+ Itpr3tf/J f 31.975 1.1342 34.2059 29.7441
BTBR T+ Itpr3tf/J m 33.5875 1.1342 35.8184 31.3566
BUB/BnJ f 30.8143 1.2125 33.1993 28.4293
BUB/BnJ m 29.4375 1.1342 31.6684 27.2066
C3H/HeJ f 28.3875 1.1342 30.6184 26.1566
C3H/HeJ m 30.125 1.1342 32.3559 27.8941
C57BL/10J f 33.9375 1.1342 36.1684 31.7066
C57BL/10J m 31.6625 1.1342 33.8934 29.4316
C57BL/6J f 32.9143 1.2125 35.2993 30.5293
C57BL/6J m 32.925 1.1342 35.1559 30.6941
C57BLKS/J f 32.675 1.1342 34.9059 30.4441
C57BLKS/J m 34.925 1.1342 37.1559 32.6941
C57BR/cdJ f 32.2667 1.3096 34.8427 29.6906
C57BR/cdJ m 32.0625 1.1342 34.2934 29.8316
C57L/J f 33.4714 1.2125 35.8564 31.0864
C57L/J m 33.4875 1.1342 35.7184 31.2566
CBA/J f 33.1 1.1342 35.3309 30.8691
CBA/J m 33.075 1.1342 35.3059 30.8441
DBA/2J f 30.6286 1.2125 33.0136 28.2436
DBA/2J m 31.475 1.1342 33.7059 29.2441
FVB/NJ f 32.925 1.1342 35.1559 30.6941
FVB/NJ m 32.725 1.1342 34.9559 30.4941
KK/HlJ f 32.35 1.1342 34.5809 30.1191
KK/HlJ m 31.9889 1.0693 34.0922 29.8855
LP/J f 32.1286 1.2125 34.5136 29.7436
LP/J m 32.7 1.1342 34.9309 30.4691
MRL/MpJ f 34.5857 1.2125 36.9707 32.2007
MRL/MpJ m 31.2667 1.3096 33.8427 28.6906
NOD.B10Sn-H2b/J f 31.47 1.0144 33.4654 29.4746
NOD.B10Sn-H2b/J m 30.95 1.1342 33.1809 28.7191
NON/ShiLtJ f 33.7571 1.2125 36.1421 31.3722
NON/ShiLtJ m 36.2125 1.1342 38.4434 33.9816
NZO/HlLtJ f 32.7667 1.0693 34.87 30.6633
NZO/HlLtJ m 34.62 1.4346 37.4419 31.7981
NZW/LacJ f 32.4625 1.1342 34.6934 30.2316
NZW/LacJ m 34.5571 1.2125 36.9421 32.1722
PL/J f 30.6875 1.1342 32.9184 28.4566
PL/J m 32.1429 1.2125 34.5278 29.7579
RIIIS/J f 37.9 1.2125 40.285 35.515
RIIIS/J m 35.8625 1.1342 38.0934 33.6316
SM/J f 34.0571 1.2125 36.4421 31.6722
SM/J m 32.7 1.1342 34.9309 30.4691
SWR/J f 30.925 1.1342 33.1559 28.6941
SWR/J m 33.5143 1.2125 35.8993 31.1293


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.0125 0.802 35.59 32.435
A/J both 34.3071 0.8574 35.9936 32.6207
AKR/J both 34.6125 1.076 36.729 32.496
BALB/cByJ both 33.5979 0.8662 35.3018 31.894
BTBR T+ Itpr3tf/J both 32.7812 0.802 34.3588 31.2037
BUB/BnJ both 30.1259 0.8301 31.7588 28.493
C3H/HeJ both 29.2563 0.802 30.8338 27.6787
C57BL/10J both 32.8 0.802 34.3775 31.2225
C57BL/6J both 32.9196 0.8301 34.5525 31.2868
C57BLKS/J both 33.8 0.802 35.3775 32.2225
C57BR/cdJ both 32.1646 0.8662 33.8685 30.4607
C57L/J both 33.4795 0.8301 35.1123 31.8466
CBA/J both 33.0875 0.802 34.665 31.51
DBA/2J both 31.0518 0.8301 32.6847 29.4189
FVB/NJ both 32.825 0.802 34.4025 31.2475
KK/HlJ both 32.1694 0.7794 33.7025 30.6364
LP/J both 32.4143 0.8301 34.0472 30.7814
MRL/MpJ both 32.9262 0.8924 34.6815 31.1709
NOD.B10Sn-H2b/J both 31.21 0.7608 32.7066 29.7134
NON/ShiLtJ both 34.9848 0.8301 36.6177 33.3519
NZO/HlLtJ both 33.6933 0.8947 35.4531 31.9335
NZW/LacJ both 33.5098 0.8301 35.1427 31.8769
PL/J both 31.4152 0.8301 33.0481 29.7823
RIIIS/J both 36.8813 0.8301 38.5141 35.2484
SM/J both 33.3786 0.8301 35.0115 31.7457
SWR/J both 32.2196 0.8301 33.8525 30.5868




  GWAS USING LINEAR MIXED MODELS